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ONTOLOGY REPORT - ANNOTATIONS


Term:olefinic compound biosynthetic process
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Accession:GO:0120255 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms:exact_synonym: alkene substituted compound anabolic process;   alkene substituted compound anabolism;   alkene substituted compound biosynthesis;   alkene substituted compound biosynthetic process;   alkene substituted compound synthesis


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,436...40,694,818
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:50073|PMID:1686470), (MGI:80407|PMID:8645611)
GO_Central
MGI
PMID:1686470 PMID:8645611 PMID:21873635 MGI:50073 MGI:80407 NCBI chr 4:1,365,725...1,373,138 JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,436...40,694,818
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
NOT|involved_in
ISO (PMID:19342457)
(PMID:9703385)
UniProt
BHF-UCL
PMID:9703385 PMID:19342457 NCBI chr 4:1,365,725...1,373,138 JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,215
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 2:47,385,244...47,444,664
Ensembl chr 2:47,385,191...47,446,538
JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
G REST RE1 silencing transcription factor involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,215
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 2:47,385,244...47,444,664
Ensembl chr 2:47,385,191...47,446,538
JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
G REST RE1 silencing transcription factor involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,462,367...54,468,363
Ensembl chr 6:54,463,759...54,468,361
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:12949260)
(MGI:2675528|PMID:12949260)
UniProt PMID:12949260 MGI:2675528 NCBI chr 6:80,110,238...80,138,165 JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,211,316
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,514,722...24,776,903
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 6:80,110,238...80,138,165 JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 6:80,110,238...80,138,165 JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,961,909
JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:1955079 RGD:1625116 NCBI chr 4:101,565,229...101,574,110 JBrowse link
G SCP2 sterol carrier protein 2 involved_in ISO (PMID:1703300) UniProt PMID:1703300 NCBI chr 6:159,191,045...159,314,985 JBrowse link
G STARD3 StAR related lipid transfer domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3039987|PMID:14963026) Ensembl
MGI
PMID:14963026 GO_REF:0000107 MGI:3039987 NCBI chr12:22,654,920...22,680,803
Ensembl chr12:22,653,032...22,688,597
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:122,234,731...122,249,889
Ensembl chr13:122,234,736...122,249,867
JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:313,325...325,089
Ensembl chr 8:313,327...325,095
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,666,348...69,700,303
Ensembl chr 6:69,666,600...69,714,463
JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:313,325...325,089
Ensembl chr 8:313,327...325,095
JBrowse link
G EGR1 early growth response 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296
JBrowse link
G MIR125A microRNA mir-125a ISO RGD PMID:23045399 RGD:26884342 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
JBrowse link
G MIR455 microRNA mir-455 ISO RGD PMID:23045399 RGD:26884342 NCBI chr 1:254,824,200...254,824,279
Ensembl chr 1:254,824,196...254,824,291
JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,560,785...98,793,318
JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:19883722 RGD:4145609 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:120,596,235...120,627,806
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G CYP19A2 cytochrome P450 19A2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1261712|PMID:9618522) Ensembl
MGI
PMID:9618522 GO_REF:0000107 MGI:1261712 NCBI chr 1:120,652,172...120,695,899
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G CYP19A3 cytochrome P450 19A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 involved_in IEA
ISO
Ensembl
RGD
PMID:8612487 GO_REF:0000107 RGD:728619 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,279,569
JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:25,822,913...25,866,871
Ensembl chr10:25,822,913...25,866,871
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:16467141 RGD:4889544 NCBI chr 4:101,565,229...101,574,110 JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:107,840,200...107,918,351
Ensembl chr 3:107,839,964...107,918,350
JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:19883722 RGD:4145609 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,347,864...48,385,464
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16534
    metabolic process 10384
      biosynthetic process 5297
        olefinic compound biosynthetic process 30
          (-)-secologanin biosynthetic process 0
          abscisic acid biosynthetic process + 0
          aldosterone biosynthetic process + 11
          all-trans-neoxanthin biosynthetic process 0
          androst-4-ene-3,17-dione biosynthetic process + 0
          chalcone biosynthetic process 0
          chanoclavine-I aldehyde biosynthetic process + 0
          cinnamic acid biosynthetic process 0
          cinnamic acid ester biosynthetic process + 0
          cortisol biosynthetic process + 10
          ferulate biosynthetic process 0
          funalenone biosynthetic process 0
          geraniol biosynthetic process 0
          helvolic acid biosynthetic process + 0
          isopentenol biosynthetic process 0
          kojic acid biosynthetic process + 0
          olefin biosynthetic process + 0
          prenol biosynthetic process 0
          progesterone biosynthetic process + 8
          sinapate biosynthetic process 0
          stilbene biosynthetic process 0
          terrequinone A biosynthetic process + 0
          testosterone biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 16534
    metabolic process 10384
      organic substance metabolic process 9953
        olefinic compound metabolic process 96
          olefinic compound biosynthetic process 30
            (-)-secologanin biosynthetic process 0
            abscisic acid biosynthetic process + 0
            aldosterone biosynthetic process + 11
            all-trans-neoxanthin biosynthetic process 0
            androst-4-ene-3,17-dione biosynthetic process + 0
            chalcone biosynthetic process 0
            chanoclavine-I aldehyde biosynthetic process + 0
            cinnamic acid biosynthetic process 0
            cinnamic acid ester biosynthetic process + 0
            cortisol biosynthetic process + 10
            ferulate biosynthetic process 0
            funalenone biosynthetic process 0
            geraniol biosynthetic process 0
            helvolic acid biosynthetic process + 0
            isopentenol biosynthetic process 0
            kojic acid biosynthetic process + 0
            olefin biosynthetic process + 0
            prenol biosynthetic process 0
            progesterone biosynthetic process + 8
            sinapate biosynthetic process 0
            stilbene biosynthetic process 0
            terrequinone A biosynthetic process + 0
            testosterone biosynthetic process + 12
paths to the root