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ONTOLOGY REPORT - ANNOTATIONS


Term:olefinic compound biosynthetic process
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Accession:GO:0120255 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms:exact_synonym: alkene substituted compound anabolic process;   alkene substituted compound anabolism;   alkene substituted compound biosynthesis;   alkene substituted compound biosynthetic process;   alkene substituted compound synthesis


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr17:25,374,285...25,436,334
Ensembl chr17:25,374,285...25,433,783
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr15:74,834,892...74,841,643
Ensembl chr15:74,834,125...74,841,643
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(MGI:50073|PMID:1686470), (MGI:80407|PMID:8645611)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:1686470 PMID:8645611 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:50073 MGI:6201960 MGI:80407 NCBI chr15:74,850,618...74,856,231
Ensembl chr15:74,851,010...74,856,318
JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr17:25,374,285...25,436,334
Ensembl chr17:25,374,285...25,433,783
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 NOT|involved_in ISO (PMID:9703385)
(PMID:19342457)
BHF-UCL
UniProt
PMID:9703385 PMID:19342457 NCBI chr15:74,850,618...74,856,231
Ensembl chr15:74,851,010...74,856,318
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:75,775,365...75,900,316
Ensembl chr 9:75,775,364...75,900,310
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:112,116,019...112,159,482
Ensembl chr 7:112,116,017...112,159,057
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:77,265,494...77,286,432
Ensembl chr 5:77,265,491...77,286,432
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:75,775,365...75,900,316
Ensembl chr 9:75,775,364...75,900,310
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:112,116,019...112,159,482
Ensembl chr 7:112,116,017...112,159,057
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:77,265,494...77,286,432
Ensembl chr 5:77,265,491...77,286,432
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf-like 1 involved_in IMP (MGI:3839065|PMID:18818293) UniProt PMID:18818293 MGI:3839065 NCBI chr 7:45,207,525...45,212,165
Ensembl chr 7:45,207,519...45,212,147
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO
IMP
(MGI:2675528|PMID:12949260) MGI
UniProt
PMID:12949260 GO_REF:0000096 MGI:2675528 MGI:4834177 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein involved_in ISO RGD
MGI
PMID:17303656 GO_REF:0000096 MGI:4417868 RGD:7243836 NCBI chr15:6,299,788...6,440,715
Ensembl chr15:6,299,788...6,440,712
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha involved_in ISO RGD
MGI
PMID:20133449 GO_REF:0000096 MGI:4417868 RGD:10059648 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:1955079 RGD:1625116 NCBI chr 3:98,842,356...98,859,794
Ensembl chr 3:98,852,194...98,859,794
JBrowse link
G Scp2 sterol carrier protein 2, liver involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:108,043,830...108,144,971
Ensembl chr 4:108,043,839...108,144,998
JBrowse link
G Stard3 START domain containing 3 acts_upstream_of_or_within IMP (MGI:3039987|PMID:14963026) MGI PMID:14963026 MGI:3039987 NCBI chr11:98,358,367...98,381,112
Ensembl chr11:98,358,368...98,381,112
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride channel, voltage-sensitive 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:20,702,435...20,717,746
Ensembl chr16:20,702,964...20,717,746
JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:108,647,044...108,660,830
Ensembl chr 5:108,646,693...108,669,672
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in IMP
ISO
(MGI:3623644|PMID:16356929) UniProt
MGI
PMID:16356929 GO_REF:0000096 MGI:3623644 MGI:4834177 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:108,647,044...108,660,830
Ensembl chr 5:108,646,693...108,669,672
JBrowse link
G Egr1 early growth response 1 involved_in IMP (MGI:82584|PMID:8703054) UniProt PMID:8703054 MGI:82584 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Mir125a microRNA 125a ISO RGD PMID:23045399 RGD:26884342 NCBI chr17:17,830,812...17,830,879
Ensembl chr17:17,830,812...17,830,879
JBrowse link
G Mir455 microRNA 455 ISO RGD PMID:23045399 RGD:26884342 NCBI chr 4:63,256,851...63,256,932
Ensembl chr 4:63,256,851...63,256,932
JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c18 aldo-keto reductase family 1, member C18 involved_in ISO (PMID:19336506) UniProt PMID:19336506 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
G Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A acts_upstream_of_or_within IDA (MGI:4352991|PMID:19398553) MGI PMID:19398553 MGI:4352991 NCBI chr 8:104,281,042...104,293,181
Ensembl chr 8:104,281,042...104,293,181
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I ISO RGD PMID:22429315 RGD:7775068 NCBI chr19:30,564,487...31,765,268
Ensembl chr19:30,564,489...31,765,033
JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c18 aldo-keto reductase family 1, member C18 involved_in ISO (PMID:16983398) UniProt PMID:16983398 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 ISO RGD PMID:19883722 RGD:4145609 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 acts_upstream_of_or_within IMP (MGI:1261712|PMID:9618522) MGI PMID:9618522 MGI:1261712 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 involved_in IDA
ISO
(MGI:1267145|PMID:9658408) UniProt
MGI
RGD
PMID:8612487 PMID:9658408 GO_REF:0000096 MGI:1267145 MGI:4417868 RGD:728619 NCBI chr11:101,077,968...101,081,188
Ensembl chr11:101,078,411...101,080,527
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr13:64,058,274...64,089,262
Ensembl chr13:64,058,266...64,089,230
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:16467141 RGD:4889544 NCBI chr 3:98,842,356...98,859,794
Ensembl chr 3:98,852,194...98,859,794
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:74,014,891...74,047,860
Ensembl chr17:74,016,955...74,047,916
JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:19883722 RGD:4145609 NCBI chr 8:25,808,474...25,815,982
Ensembl chr 8:25,806,555...25,815,982
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28607
    metabolic process 11218
      biosynthetic process 5733
        olefinic compound biosynthetic process 30
          (-)-secologanin biosynthetic process 0
          abscisic acid biosynthetic process + 0
          aldosterone biosynthetic process + 11
          all-trans-neoxanthin biosynthetic process 0
          androst-4-ene-3,17-dione biosynthetic process + 0
          chalcone biosynthetic process 0
          chanoclavine-I aldehyde biosynthetic process + 0
          cinnamic acid biosynthetic process 0
          cinnamic acid ester biosynthetic process + 0
          cortisol biosynthetic process + 9
          ferulate biosynthetic process 0
          funalenone biosynthetic process 0
          geraniol biosynthetic process 0
          helvolic acid biosynthetic process + 0
          isopentenol biosynthetic process 0
          kojic acid biosynthetic process + 0
          olefin biosynthetic process + 0
          prenol biosynthetic process 0
          progesterone biosynthetic process + 8
          sinapate biosynthetic process 0
          stilbene biosynthetic process 0
          terrequinone A biosynthetic process + 0
          testosterone biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 28607
    metabolic process 11218
      organic substance metabolic process 10801
        olefinic compound metabolic process 151
          olefinic compound biosynthetic process 30
            (-)-secologanin biosynthetic process 0
            abscisic acid biosynthetic process + 0
            aldosterone biosynthetic process + 11
            all-trans-neoxanthin biosynthetic process 0
            androst-4-ene-3,17-dione biosynthetic process + 0
            chalcone biosynthetic process 0
            chanoclavine-I aldehyde biosynthetic process + 0
            cinnamic acid biosynthetic process 0
            cinnamic acid ester biosynthetic process + 0
            cortisol biosynthetic process + 9
            ferulate biosynthetic process 0
            funalenone biosynthetic process 0
            geraniol biosynthetic process 0
            helvolic acid biosynthetic process + 0
            isopentenol biosynthetic process 0
            kojic acid biosynthetic process + 0
            olefin biosynthetic process + 0
            prenol biosynthetic process 0
            progesterone biosynthetic process + 8
            sinapate biosynthetic process 0
            stilbene biosynthetic process 0
            terrequinone A biosynthetic process + 0
            testosterone biosynthetic process + 12
paths to the root