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ONTOLOGY REPORT - ANNOTATIONS

Term:olefinic compound biosynthetic process
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Accession:GO:0120255 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms:exact_synonym: alkene substituted compound anabolic process;   alkene substituted compound anabolism;   alkene substituted compound biosynthesis;   alkene substituted compound biosynthetic process;   alkene substituted compound synthesis


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IMP (PMID:19342457) UniProt PMID:19342457 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in ISO
IBA
IEA
IDA
IMP		 (PMID:2256920)
(PMID:19342457)		 RGD
GO_Central
TreeGrafter
BHF-UCL
UniProt		 PMID:2256920 PMID:11832364 PMID:19342457 GO_REF:0000033 GO_REF:0000118 RGD:727991 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within		 IMP
ISO
IEA
IBA
IDA		 (PMID:19342457)
(PMID:1686470), (PMID:8645611)
(PMID:1741400), (PMID:2256920), (PMID:23322723)		 UniProt
MGI
TreeGrafter
GO_Central
BHF-UCL		 PMID:1686470 PMID:1741400 PMID:2256920 PMID:8645611 PMID:19342457 More... GO_REF:0000033 GO_REF:0000118 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
androst-4-ene-3,17-dione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INHBA inhibin subunit beta A acts_upstream_of_or_within ISO (PMID:32954300) MGI PMID:32954300 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IMP (PMID:19342457) UniProt PMID:19342457 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in IDA
IMP		 (PMID:8506298)
(PMID:19342457), (PMID:2022736)		 BHF-UCL
UniProt		 PMID:2022736 PMID:8506298 PMID:19342457 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
NOT|involved_in		 IMP (PMID:19342457)
(PMID:9703385)		 UniProt
BHF-UCL		 PMID:9703385 PMID:19342457 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IDA (PMID:19584291) BHF-UCL PMID:19584291 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IDA (PMID:19584291) BHF-UCL PMID:19584291 NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IDA (PMID:16981135) UniProt PMID:16981135 NCBI chr11:11,963,036...12,009,745
Ensembl chr11:11,956,207...12,009,769 		JBrowse link
G REST RE1 silencing transcription factor involved_in IMP (PMID:19342457) UniProt PMID:19342457 NCBI chr 4:56,907,900...56,935,844
Ensembl chr 4:56,907,876...56,966,808 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IDA (PMID:19584291) BHF-UCL PMID:19584291 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IDA (PMID:19584291) BHF-UCL PMID:19584291 NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IDA (PMID:16981135) UniProt PMID:16981135 NCBI chr11:11,963,036...12,009,745
Ensembl chr11:11,956,207...12,009,769 		JBrowse link
G REST RE1 silencing transcription factor involved_in IMP (PMID:19342457) UniProt PMID:19342457 NCBI chr 4:56,907,900...56,935,844
Ensembl chr 4:56,907,876...56,966,808 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:49,360,515...49,375,116
Ensembl chr19:49,361,783...49,375,116 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA
IMP		 (PMID:12949260) Ensembl
UniProt		 PMID:12949260 GO_REF:0000107 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IDA (PMID:16527843) UniProt PMID:16527843 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA
ISO		 Ensembl
RGD		 PMID:17303656 GO_REF:0000107 RGD:7243836 NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300 		JBrowse link
G WNT4 Wnt family member 4 involved_in IDA (PMID:16981135) UniProt PMID:16981135 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IDA (PMID:16981135) UniProt PMID:16981135 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin involved_in TAS (PMID:10822232) GO_Central PMID:10822232 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHB follicle stimulating hormone subunit beta involved_in TAS (PMID:14557487) BHF-UCL PMID:14557487 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:1955079 RGD:1625116 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G LHB luteinizing hormone subunit beta involved_in TAS (PMID:14557487) BHF-UCL PMID:14557487 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G SCP2 sterol carrier protein 2 involved_in IDA (PMID:1703300) UniProt PMID:1703300 NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698 		JBrowse link
G STARD3 StAR related lipid transfer domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14963026) Ensembl
MGI		 PMID:14963026 GO_REF:0000107 NCBI chr17:39,637,144...39,664,201
Ensembl chr17:39,637,090...39,664,201 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IMP (PMID:29403011) UniProt PMID:29403011 NCBI chr 3:184,346,185...184,361,605
Ensembl chr 3:184,346,185...184,361,650 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IMP (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IMP (PMID:18628520), (PMID:23132696) UniProt PMID:18628520 PMID:23132696 NCBI chr 1:9,234,774...9,271,337
Ensembl chr 1:9,234,774...9,271,337 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IMP (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895 		JBrowse link
G EGR1 early growth response 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G MIR125A microRNA 125a ISO RGD PMID:23045399 RGD:26884342 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MIR455 microRNA 455 ISO RGD PMID:23045399 RGD:26884342 NCBI chr 9:114,209,434...114,209,529
Ensembl chr 9:114,209,434...114,209,529 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IMP (PMID:19336506) UniProt PMID:19336506 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G GPRC6A G protein-coupled receptor class C group 6 member A involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:116,792,085...116,829,240
Ensembl chr 6:116,792,085...116,829,083 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:22429315 GO_REF:0000107 RGD:7775068 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IMP (PMID:16983398) UniProt PMID:16983398 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:19883722 RGD:4145609 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9618522) Ensembl
MGI		 PMID:9618522 GO_REF:0000107 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 involved_in ISO
ISS
IEA		 RGD
UniProt
Ensembl		 PMID:8612487 GO_REF:0000024 GO_REF:0000107 RGD:728619 NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214 		JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 involved_in IEA UniProt GO_REF:0000041 NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:16467141 RGD:4889544 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 involved_in IDA (PMID:10898110) UniProt PMID:10898110 NCBI chr 2:31,522,480...31,663,009
Ensembl chr 2:31,522,480...31,580,938 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:19883722 RGD:4145609 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    metabolic process 12464
      organic substance metabolic process 11967
        olefinic compound metabolic process 185
          olefinic compound biosynthetic process 37
            (-)-secologanin biosynthetic process 0
            abscisic acid biosynthetic process + 0
            aldosterone biosynthetic process + 11
            all-trans-neoxanthin biosynthetic process 0
            andrastin A biosynthetic process 0
            androst-4-ene-3,17-dione biosynthetic process + 1
            chalcone biosynthetic process 0
            chanoclavine-I aldehyde biosynthetic process + 0
            cinnamic acid biosynthetic process 0
            cinnamic acid ester biosynthetic process + 0
            cortisol biosynthetic process + 10
            eugenol biosynthetic process 0
            ferulate biosynthetic process 0
            funalenone biosynthetic process 0
            geraniol biosynthetic process 0
            helvolic acid biosynthetic process + 0
            isopentenol biosynthetic process 0
            kojic acid biosynthetic process + 0
            olefin biosynthetic process + 0
            paxilline biosynthetic process 0
            prenol biosynthetic process 0
            progesterone biosynthetic process + 12
            sinapate biosynthetic process 0
            stilbene biosynthetic process 0
            terrequinone A biosynthetic process + 0
            testosterone biosynthetic process + 14
            viridicatumtoxin biosynthetic process 0
            vomitoxin biosynthetic process 0
paths to the root