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ONTOLOGY REPORT - ANNOTATIONS


Term:tight junction organization
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Accession:GO:0120193 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
Synonyms:exact_synonym: occluding cell junction organization;   occluding junction organization


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tight junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn19 claudin 19 acts_upstream_of_or_within ISO MGI:3583804 (MGI:3583407|PMID:15883201) RGD PMID:15883201 MGI:3583407 NCBI chr 5:138,300,692...138,307,982
Ensembl chr 5:138,300,107...138,305,683
JBrowse link
G Cldn9 claudin 9 acts_upstream_of_or_within ISO (MGI:3696284|PMID:17130295) RGD PMID:17130295 MGI:3696284 NCBI chr10:13,003,010...13,004,441
Ensembl chr10:13,003,011...13,004,441
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:5766597|PMID:26024086) RGD PMID:26024086 MGI:5766597 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Ocln occludin involved_in ISO (MGI:6369916|PMID:30734065) RGD PMID:30734065 MGI:6369916 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Plec plectin involved_in ISO
IEA
MGI:3721885 (MGI:5790023|PMID:26519478)
GO_REF:0000107
RGD
Ensembl
PMID:26519478 GO_REF:0000107 MGI:5790023 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5286317 (MGI:5913245|PMID:28179432)
Ensembl
RGD
PMID:28179432 GO_REF:0000107 MGI:5913245 NCBI chr 5:75,147,245...75,320,873
Ensembl chr 5:75,143,867...75,319,765
JBrowse link
bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07024637.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:9,772,688...9,847,444 JBrowse link
G AABR07037477.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:21,944,613...21,945,305 JBrowse link
G AABR07037590.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:24,629,306...24,629,998 JBrowse link
G Actn4 actinin alpha 4 involved_in ISO (MGI:3794927|PMID:18332111) RGD PMID:18332111 MGI:3794927 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Afdn afadin, adherens junction formation factor involved_in ISO (PMID:27815408) RGD PMID:27815408 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type NOT|involved_in ISO (MGI:3789553|PMID:17403930) RGD PMID:17403930 MGI:3789553 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 NOT|involved_in ISO (MGI:5488571|PMID:22832496) RGD PMID:22832496 MGI:5488571 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:221,504,150...221,516,191
Ensembl chr 1:221,504,170...221,516,110
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO MGI:2389020 (MGI:3574751|PMID:15775979) RGD PMID:15775979 MGI:3574751 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cgn cingulin acts_upstream_of_or_within ISO (MGI:5562592|PMID:24385485) RGD PMID:24385485 MGI:5562592 NCBI chr 2:195,909,691...195,937,130
Ensembl chr 2:195,909,626...195,935,878
JBrowse link
G Cldn1 claudin 1 involved_in ISO
IBA
(PMID:25849148), (PMID:26607202)
PMID:21873635
RGD PMID:25849148 PMID:26607202, PMID:21873635 RGD:13792537 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn10 claudin 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:104,026,590...104,115,748
Ensembl chr15:104,026,601...104,115,748
JBrowse link
G Cldn11 claudin 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Cldn14 claudin 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:34,132,581...34,142,813
Ensembl chr11:34,132,581...34,142,753
JBrowse link
G Cldn15 claudin 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:22,738,198...22,750,392
Ensembl chr12:22,738,195...22,748,860
JBrowse link
G Cldn16 claudin 16 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:77,683,942...77,703,232
Ensembl chr11:77,681,794...77,703,255
JBrowse link
G Cldn17 claudin 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:28,477,184...28,478,360
Ensembl chr11:28,477,184...28,478,360
JBrowse link
G Cldn18 claudin 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:107,933,725...107,960,656
Ensembl chr 8:107,934,860...107,952,530
JBrowse link
G Cldn19 claudin 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:138,300,692...138,307,982
Ensembl chr 5:138,300,107...138,305,683
JBrowse link
G Cldn2 claudin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cldn20 claudin 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:44,443,218...44,447,595
Ensembl chr 1:44,446,765...44,447,424
JBrowse link
G Cldn22 claudin 22 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:47,534,349...47,535,358
Ensembl chr16:47,534,349...47,535,358
JBrowse link
G Cldn23 claudin 23 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:59,988,603...59,990,327
Ensembl chr16:59,988,603...59,990,326
JBrowse link
G Cldn24 claudin 24 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:47,536,814...47,537,476
Ensembl chr16:47,536,814...47,537,476
JBrowse link
G Cldn25 claudin 25 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:53,360,490...53,362,387
Ensembl chr 8:53,361,323...53,362,006
JBrowse link
G Cldn3 claudin 3 involved_in ISO
IBA
(PMID:25849148)
PMID:21873635
RGD PMID:25849148, PMID:21873635 RGD:13792537 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn34a claudin 34A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:23,371,171...23,415,287
Ensembl chr  X:23,414,354...23,414,989
JBrowse link
G Cldn34b claudin 34B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:43,780,712...43,786,767
Ensembl chr  X:43,780,960...43,781,586
JBrowse link
G Cldn34c4 claudin 34C4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:97,261,326...97,266,967
Ensembl chr  X:97,261,354...97,262,013
JBrowse link
G Cldn34d claudin 34D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:43,870,402...43,878,881
Ensembl chr  X:43,870,402...43,878,881
JBrowse link
G Cldn34e claudin 34E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:44,999,482...45,006,621
Ensembl chr  X:44,999,725...45,000,363
JBrowse link
G Cldn4 claudin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn5 claudin 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Cldn6 claudin 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:12,999,256...13,002,860
Ensembl chr10:13,000,090...13,002,862
JBrowse link
G Cldn7 claudin 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Cldn8 claudin 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Cldn9 claudin 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:13,003,010...13,004,441
Ensembl chr10:13,003,011...13,004,441
JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO (PMID:8636221) RGD PMID:8636221 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO
IEA
(PMID:17332497)
GO_REF:0000107
RGD
Ensembl
PMID:17332497 GO_REF:0000107 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:15254234) RGD PMID:15254234 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Esam endothelial cell adhesion molecule involved_in ISO (PMID:26607202) RGD PMID:26607202 NCBI chr 8:39,997,875...40,008,802
Ensembl chr 8:39,997,875...40,008,809
JBrowse link
G Frmpd2 FERM and PDZ domain containing 2 involved_in ISO (PMID:19706687) RGD PMID:19706687 NCBI chr16:9,745,171...9,879,490 JBrowse link
G Grhl2 grainyhead-like transcription factor 2 involved_in ISO (PMID:25152456) RGD PMID:25152456 NCBI chr 7:76,058,623...76,197,360
Ensembl chr 7:76,059,386...76,197,856
JBrowse link
G Itgb1 integrin subunit beta 1 IMP RGD PMID:18579774 RGD:2325293 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G LOC100362173 rCG36365-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:43,713,128...43,746,425
Ensembl chr  X:43,745,604...43,746,236
JBrowse link
G LOC102554799 uncharacterized LOC102554799 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:1,500,272...1,505,254
Ensembl chr14:1,499,711...1,505,085
JBrowse link
G LOC680190 hypothetical protein LOC680190 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:43,289,631...43,294,392
Ensembl chr  X:43,293,551...43,294,177
JBrowse link
G LOC685699 hypothetical protein LOC685699 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:23,464,884...23,469,812
Ensembl chr  X:23,464,863...23,469,041
JBrowse link
G LOC685747 hypothetical protein LOC685747 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:24,058,965...24,061,851
Ensembl chr  X:24,059,516...24,061,857
JBrowse link
G LOC685762 hypothetical protein LOC685762 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:24,117,023...24,121,003
Ensembl chr  X:24,117,026...24,120,987
JBrowse link
G LOC685789 hypothetical protein LOC685789 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:22,681,975...22,749,355
Ensembl chr  X:22,674,759...22,737,523
JBrowse link
G Marveld2 MARVEL domain containing 2 involved_in ISO (PMID:20164257), (PMID:23073616) RGD PMID:20164257 PMID:23073616 NCBI chr 2:30,612,746...30,634,308
Ensembl chr 2:30,612,106...30,634,243
JBrowse link
G Marveld3 MARVEL domain containing 3 involved_in IBA
ISO
PMID:21873635
(PMID:20164257)
RGD PMID:20164257, PMID:21873635 RGD:13792537 NCBI chr19:41,710,076...41,724,923
Ensembl chr19:41,710,102...41,724,923
JBrowse link
G Micall2 MICAL-like 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5508599|PMID:18094055)
UniProt
RGD
PMID:18094055 GO_REF:0000024 MGI:5508599 NCBI chr12:16,988,013...17,016,794
Ensembl chr12:16,988,136...17,016,791
JBrowse link
G Mpp7 membrane palmitoylated protein 7 involved_in ISO (PMID:17332497) RGD PMID:17332497 NCBI chr17:60,057,077...60,250,303
Ensembl chr17:60,059,949...60,250,352
JBrowse link
G Mtdh metadherin IEP RGD PMID:15383321 RGD:1359738 NCBI chr 7:72,771,018...72,830,599
Ensembl chr 7:72,772,440...72,827,908
JBrowse link
G Ocln occludin involved_in ISO (PMID:20164257), (PMID:26607202) RGD PMID:20164257 PMID:26607202 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Pard3 par-3 family cell polarity regulator involved_in IMP PMID:18082612 UniProt PMID:18082612 RGD:8553352 NCBI chr19:60,017,746...60,580,628
Ensembl chr19:60,017,746...60,580,651
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5819325|PMID:27336173)
UniProt
Ensembl
RGD
PMID:27336173 GO_REF:0000024 GO_REF:0000107 MGI:5819325 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO (PMID:26607202) RGD PMID:26607202 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pof1b POF1B, actin binding protein involved_in ISO (PMID:21940798) RGD PMID:21940798 NCBI chr  X:84,099,618...84,167,717
Ensembl chr  X:84,099,618...84,167,717
JBrowse link
G Rab13 RAB13, member RAS oncogene family involved_in ISS
ISO
GO_REF:0000024
(PMID:12058051), (PMID:15096524)
UniProt
RGD
PMID:12058051 PMID:15096524 GO_REF:0000024 NCBI chr 2:189,581,209...189,586,358
Ensembl chr 2:189,581,644...189,586,338
JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISO
ISS
(PMID:18097473)
(MGI:3772552|PMID:18097473)
GO_REF:0000024
RGD
UniProt
PMID:18097473 GO_REF:0000024 MGI:3772552 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Samt3 spermatogenesis associated multipass transmembrane protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:54,553,870...54,556,708
Ensembl chr  X:54,553,878...54,556,771
JBrowse link
G Samt4 spermatogenesis associated multipass transmembrane protein 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:24,362,079...24,364,320
Ensembl chr  X:24,362,076...24,364,322
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2445832|MGI:3522206 (MGI:4421610|PMID:20047077) RGD PMID:20047077 MGI:4421610 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tbcd tubulin folding cofactor D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:110,643,693...110,800,493
Ensembl chr10:110,643,759...110,800,493
JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:8636221) RGD PMID:8636221 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO MGI:2665014 (MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:3759355 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
negative regulation of bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO
IEA
(PMID:25816133)
GO_REF:0000107
RGD
Ensembl
PMID:25816133 GO_REF:0000107 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:O75116 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Rps6 ribosomal protein S6 IDA RGD PMID:25217631 RGD:11041641 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
positive regulation of bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn1 claudin 1 IMP RGD PMID:22684624 RGD:11341733 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn3 claudin 3 involved_in ISO (PMID:20655293) RGD PMID:20655293 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:25323998) RGD PMID:25323998 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:27815408) RGD PMID:27815408 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Gcg glucagon involved_in ISO (PMID:25050009) RGD PMID:25050009 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Il17a interleukin 17A involved_in IEA
ISO
GO_REF:0000107
(MGI:5788042|PMID:26431948)
Ensembl
RGD
PMID:26431948 GO_REF:0000107 MGI:5788042 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Nphp1 nephrocystin 1 involved_in ISO
IEA
(PMID:19755384)
GO_REF:0000107
RGD
Ensembl
PMID:19755384 GO_REF:0000107 NCBI chr 3:120,316,048...120,370,089
Ensembl chr 3:120,316,047...120,373,500
JBrowse link
G Nphp4 nephrocystin 4 involved_in ISO (PMID:19755384) RGD PMID:19755384 NCBI chr 5:169,647,581...169,744,662
Ensembl chr 5:169,659,188...169,744,660
JBrowse link
positive regulation of tight junction disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23633925 RGD:12791991 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO (PMID:18718461) RGD PMID:18718461 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO UniProtKB:P10600 (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
regulation of bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11r F11 receptor involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3583769 (MGI:5494335|PMID:23610556)
Ensembl
RGD
PMID:23610556 GO_REF:0000107 MGI:5494335 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739
JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:19509333 RGD:6784505 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 involved_in ISO (MGI:5297273|PMID:22046243) RGD PMID:22046243 MGI:5297273 NCBI chr 9:81,555,914...81,560,931
Ensembl chr 9:81,559,605...81,560,594
JBrowse link
G Myo1c myosin 1C involved_in ISO (PMID:21402783) RGD PMID:21402783 NCBI chr10:63,803,311...63,819,614
Ensembl chr10:63,803,309...63,819,614
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (MGI:4819049|PMID:20504882) RGD PMID:20504882 MGI:4819049 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Pkp2 plakophilin 2 IMP RGD PMID:19509333 RGD:6784505 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO
IEA
(PMID:15905176)
GO_REF:0000107
RGD
Ensembl
PMID:15905176 GO_REF:0000107 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkch protein kinase C, eta involved_in ISO
ISS
(PMID:19114660)
GO_REF:0000024
RGD
UniProt
PMID:19114660 GO_REF:0000024 NCBI chr 6:96,479,243...96,677,368
Ensembl chr 6:96,479,430...96,676,225
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 involved_in ISO (PMID:22855531) RGD PMID:22855531 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Cldn11 claudin 11 involved_in ISO
IEA
(PMID:30734065)
GO_REF:0000107
RGD
Ensembl
PMID:30734065 GO_REF:0000107 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Cldn12 claudin 12 NOT|involved_in ISO (MGI:6368067|PMID:31511021) RGD PMID:31511021 MGI:6368067 NCBI chr 4:25,681,561...25,692,547
Ensembl chr 4:25,686,392...25,692,547
JBrowse link
G Cldn5 claudin 5 involved_in ISO (MGI:6369916|PMID:30734065) RGD PMID:30734065 MGI:6369916 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Ephb2 Eph receptor B2 IDA RGD PMID:33722292 RGD:127285641 NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:99,413,184...99,566,356
Ensembl chr 5:99,413,187...99,566,318
JBrowse link
G Patj PATJ, crumbs cell polarity complex component involved_in ISO
IBA
ISS
(PMID:15738264)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:15738264, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:117,038,548...117,340,308
Ensembl chr 5:117,052,260...117,340,336
JBrowse link
tricellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lsr lipolysis stimulated lipoprotein receptor involved_in ISO (MGI:5700290|PMID:22671589), (MGI:6316553|PMID:21245199) RGD PMID:21245199 PMID:22671589 MGI:5700290 MGI:6316553 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          cell junction organization 798
            cell-cell junction organization 229
              tight junction organization 104
                tight junction assembly + 98
                tight junction disassembly + 3
paths to the root