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ONTOLOGY REPORT - ANNOTATIONS


Term:procentriole
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Accession:GO:0120098 term browser browse the term
Definition:A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells.



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procentriole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cep152 centrosomal protein 152 located_in ISO (PMID:24997597) RGD PMID:24997597 NCBI chr 3:112,803,185...112,878,298
Ensembl chr 3:112,810,425...112,878,458
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G Cep192 centrosomal protein 192 located_in ISO (PMID:24997597) RGD PMID:24997597 NCBI chr18:61,346,957...61,458,405
Ensembl chr18:61,332,158...61,458,379
JBrowse link
G Plk4 polo-like kinase 4 located_in ISO (PMID:24997597) RGD PMID:24997597 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
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Term paths to the root
Path 1
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  cellular_component 19187
    cellular anatomical entity 18928
      procentriole 3
Path 2
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  cellular_component 19187
    cellular anatomical entity 18928
      intracellular anatomical structure 14074
        cytoplasm 11200
          procentriole 3
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