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ONTOLOGY REPORT - ANNOTATIONS

Term:apical plasma membrane urothelial plaque
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Accession:GO:0120001 term browser browse the term
Definition:A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.
Synonyms:exact_synonym: asymmetric unit membrane
 related_synonym: AUM

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apical plasma membrane urothelial plaque term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upk1a uroplakin 1A located_in
is_active_in		 IEA
ISO		 (PMID:22323295) Ensembl
MGI		 PMID:22323295 GO_REF:0000107 NCBI chrNW_004936570:633,933...641,429
Ensembl chrNW_004936570:634,067...642,605 		JBrowse link
G Upk1b uroplakin 1B located_in
is_active_in		 IEA
ISO		 (PMID:22323295) Ensembl
MGI		 PMID:22323295 GO_REF:0000107 NCBI chrNW_004936536:6,178,159...6,208,273
Ensembl chrNW_004936536:6,178,127...6,208,913 		JBrowse link
G Upk2 uroplakin 2 is_active_in ISO (PMID:22323295) MGI PMID:22323295 NCBI chrNW_004936542:3,929,555...3,931,754
Ensembl chrNW_004936542:3,929,535...3,931,769 		JBrowse link
G Upk3a uroplakin 3A located_in
is_active_in		 IEA
ISO		 (PMID:22323295)
(PMID:26046524)		 Ensembl
MGI		 PMID:22323295 PMID:26046524 GO_REF:0000107 NCBI chrNW_004936629:4,421,977...4,427,783
Ensembl chrNW_004936629:4,421,966...4,427,312 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16742
    cellular anatomical entity 16649
      cell periphery 5386
        plasma membrane 4936
          apical plasma membrane urothelial plaque 4
Path 2
Term Annotations click to browse term
  cellular_component 16742
    cellular anatomical entity 16649
      cell periphery 5386
        plasma membrane 4936
          plasma membrane region 1347
            apical plasma membrane 412
              apical plasma membrane urothelial plaque 4
paths to the root