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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA NAD+-cap (NAD+-forming) hydrolase activity
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Accession:GO:0110152 term browser browse the term
Definition:Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.
Comment:This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Synonyms:xref: RHEA:60880


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RNA NAD+-cap (NAD+-forming) hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DXO decapping exoribonuclease enables ISS
IEA		 UniProt
RHEA		 GO_REF:0000024 GO_REF:0000116 NCBI chr 6:31,969,815...31,972,138
Ensembl chr 6:31,969,810...31,972,290 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19587
    catalytic activity 6011
      catalytic activity, acting on a nucleic acid 653
        catalytic activity, acting on RNA 419
          RNA NAD+-cap (NAD+-forming) hydrolase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 19587
    catalytic activity 6011
      hydrolase activity 2631
        hydrolase activity, acting on acid anhydrides 851
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 851
            RNA NAD+-cap (NAD+-forming) hydrolase activity 1
paths to the root