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ONTOLOGY REPORT - ANNOTATIONS


Term:SHREC2 complex
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Accession:GO:0110129 term browser browse the term
Definition:A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.


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  cellular_component 20609
    protein-containing complex 6092
      catalytic complex 1487
        histone deacetylase complex 81
          SHREC2 complex 0
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  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13257
        membrane-bounded organelle 11448
          intracellular membrane-bounded organelle 10704
            nucleus 7183
              nuclear lumen 4262
                nucleoplasm 3399
                  histone deacetylase complex 81
                    SHREC2 complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.