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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of calcineurin-mediated signaling
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Accession:GO:0106056 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.


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regulation of calcineurin-mediated signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc8a2 solute carrier family 8 member A2 IEA
ISO
GO_REF:0000107
(MGI:MGI:6282180|PMID:29274751)
Ensembl
RGD
PMID:29274751 GO_REF:0000107, MGI:MGI:6282180 NCBI chr 1:78,029,555...78,054,042
Ensembl chr 1:78,025,995...78,060,111
JBrowse link
negative regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:MGI:5554485|PMID:24234654) RGD PMID:24234654 MGI:MGI:5554485 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 IMP
ISO
PMID:19287093
(MGI:MGI:6368228|PMID:25147342)
(PMID:15955804), (PMID:19287093), (PMID:25147342)
RGD PMID:15955804, PMID:19287093, PMID:25147342, PMID:19287093 MGI:MGI:6368228, RGD:10047333 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 ISO
ISS
(PMID:10593895)
GO_REF:0000024
RGD
UniProt
PMID:10593895 GO_REF:0000024 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989
JBrowse link
G Cmya5 cardiomyopathy associated 5 ISO MGI:MGI:107164 (MGI:MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:MGI:5056263 NCBI chr 2:22,646,694...22,744,536
Ensembl chr 2:22,646,712...22,744,407
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 ISO (PMID:16511445) RGD PMID:16511445 NCBI chr 7:61,785,423...61,816,775
Ensembl chr 7:61,786,309...61,798,729
JBrowse link
G Fhl2 four and a half LIM domains 2 IMP
IBA
ISO
PMID:22851699
PMID:21873635
(MGI:MGI:5444535|PMID:22851699)
(PMID:22851699)
RGD PMID:22851699, PMID:22851699, PMID:21873635 MGI:MGI:5444535, RGD:13601990, RGD:13792537 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISS
ISO
IEA
GO_REF:0000024
(PMID:9072970)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9072970 GO_REF:0000024, GO_REF:0000107 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Homer2 homer scaffold protein 2 ISS
ISO
GO_REF:0000024
(PMID:18218901)
UniProt
RGD
PMID:18218901 GO_REF:0000024 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Homer3 homer scaffold protein 3 ISS
ISO
GO_REF:0000024
(PMID:18218901)
UniProt
RGD
PMID:18218901 GO_REF:0000024 NCBI chr16:20,880,447...20,890,968
Ensembl chr16:20,881,518...20,890,949
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (MGI:MGI:3795069|PMID:18347059) RGD PMID:18347059 MGI:MGI:3795069 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO (MGI:MGI:3795069|PMID:18347059) RGD PMID:18347059 MGI:MGI:3795069 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myoz1 myozenin 1 ISO (MGI:MGI:3831256|PMID:18846255) RGD PMID:18846255 MGI:MGI:3831256 NCBI chr15:4,077,066...4,084,306
Ensembl chr15:4,077,091...4,084,314
JBrowse link
G Myoz2 myozenin 2 ISO (MGI:MGI:3513659|PMID:15543153) RGD PMID:15543153 MGI:MGI:3513659 NCBI chr 2:227,180,887...227,207,629
Ensembl chr 2:227,180,886...227,207,635
JBrowse link
G Prnp prion protein ISO (MGI:MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:MGI:4943618 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Rcan1 regulator of calcineurin 1 ISS
ISO
GO_REF:0000024
(PMID:12809556)
UniProt
RGD
PMID:12809556 GO_REF:0000024 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Tbc1d10c TBC1 domain family, member 10C ISO MGI:MGI:5578034 (MGI:MGI:5576870|PMID:23109291) RGD PMID:23109291 MGI:MGI:5576870 NCBI chr 1:219,431,094...219,439,102
Ensembl chr 1:219,431,997...219,438,779
JBrowse link
positive regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 IMP PMID:22343722 UniProt PMID:22343722 RGD:13507305 NCBI chr 6:99,356,509...99,361,909
Ensembl chr 6:99,356,509...99,361,909
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP PMID:16306226 BHF-UCL PMID:16306226 RGD:2312613 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Camta1 calmodulin binding transcription activator 1 ISO (PMID:23853098) RGD PMID:23853098 NCBI chr 5:168,138,207...169,017,295
Ensembl chr 5:168,141,372...169,017,295
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 ISO MGI:MGI:3053071|MGI:MGI:5609428 (MGI:MGI:5451119|PMID:23123061) RGD PMID:23123061 MGI:MGI:5451119 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cherp calcium homeostasis endoplasmic reticulum protein ISO (PMID:12656674) RGD PMID:12656674 NCBI chr16:19,068,783...19,081,837
Ensembl chr16:19,068,783...19,081,837
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 ISO
ISS
(PMID:18815128)
GO_REF:0000024
RGD
UniProt
PMID:18815128 GO_REF:0000024 NCBI chr 1:192,169,634...192,173,228
Ensembl chr 1:192,169,841...192,173,253
JBrowse link
G Cib1 calcium and integrin binding 1 ISO
IMP
(PMID:20639889)
(MGI:MGI:4821678|PMID:20639889)
RGD PMID:20639889, PMID:20639889 MGI:MGI:4821678, RGD:8554486 NCBI chr 1:142,014,962...142,020,461
Ensembl chr 1:142,014,958...142,020,525
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO
IEA
MGI:MGI:96083 (MGI:MGI:3830391|PMID:19179536)
GO_REF:0000107
RGD
Ensembl
PMID:19179536 GO_REF:0000107, MGI:MGI:3830391 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Igf1 insulin-like growth factor 1 ISO
IEA
(PMID:19654000)
GO_REF:0000107
RGD
Ensembl
PMID:19654000 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 ISO (PMID:20026769)
(MGI:MGI:4442539|PMID:20026769)
RGD PMID:20026769 MGI:MGI:4442539 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Nrg1 neuregulin 1 ISO
IEA
MGI:MGI:95411 (MGI:MGI:3830391|PMID:19179536)
GO_REF:0000107
RGD
Ensembl
PMID:19179536 GO_REF:0000107, MGI:MGI:3830391 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 ISO
IEA
(PMID:23853098)
GO_REF:0000107
RGD
Ensembl
PMID:23853098 GO_REF:0000107 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718
JBrowse link
G RGD1564899 similar to chromosome 10 open reading frame 71 IMP
ISO
PMID:28717008
(MGI:MGI:5917329|PMID:28717008)
RGD PMID:28717008, PMID:28717008 MGI:MGI:5917329, RGD:13602000 NCBI chr16:8,879,907...8,907,462
Ensembl chr16:8,881,138...8,885,797
JBrowse link
G Slc12a1 solute carrier family 12 member 1 ISO (MGI:MGI:4947009|PMID:21228109) RGD PMID:21228109 MGI:MGI:4947009 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO (PMID:22688515) RGD PMID:22688515 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Sppl3 signal peptide peptidase like 3 ISO (PMID:25384971)
(MGI:MGI:5640905|PMID:25384971)
RGD PMID:25384971 MGI:MGI:5640905 NCBI chr12:47,276,485...47,360,552
Ensembl chr12:47,276,476...47,360,507
JBrowse link
G Tmem110 transmembrane protein 110 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr16:6,903,212...6,958,786
Ensembl chr16:6,903,212...6,958,783
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:16803872) RGD PMID:16803872 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efhb EF hand domain family, member B ISO (PMID:30481768) RGD PMID:30481768 NCBI chr 9:47,988...120,800
Ensembl chr 9:47,724...120,799
JBrowse link
G Mir1 microRNA 1 ISO (MGI:MGI:3842072|PMID:19188439) RGD PMID:19188439 MGI:MGI:3842072 NCBI chr18:2,054,933...2,055,019 JBrowse link
G Mir1b microRNA 1b ISO (MGI:MGI:62936|PMID:6466370) RGD PMID:6466370 MGI:MGI:62936 NCBI chr 3:175,769,716...175,769,800
Ensembl chr 3:175,769,716...175,769,800
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 ISO (MGI:MGI:3842072|PMID:19188439) RGD PMID:19188439 MGI:MGI:3842072 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Rcan1 regulator of calcineurin 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rcan2 regulator of calcineurin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:19,518,568...19,749,145
Ensembl chr 9:19,518,558...19,749,145
JBrowse link
G Rcan3 RCAN family member 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:153,773,461...153,790,271
Ensembl chr 5:153,773,663...153,790,157
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      signal transduction 7015
        regulation of signal transduction 2997
          regulation of intracellular signal transduction 1707
            regulation of calcium-mediated signaling 109
              regulation of calcineurin-mediated signaling 41
                negative regulation of calcineurin-mediated signaling + 16
                positive regulation of calcineurin-mediated signaling + 18
                regulation of calcineurin-NFAT signaling cascade + 40
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of cellular process 12560
          signal transduction 7015
            intracellular signal transduction 2615
              second-messenger-mediated signaling 484
                calcium-mediated signaling 235
                  regulation of calcium-mediated signaling 109
                    regulation of calcineurin-mediated signaling 41
                      negative regulation of calcineurin-mediated signaling + 16
                      positive regulation of calcineurin-mediated signaling + 18
                      regulation of calcineurin-NFAT signaling cascade + 40
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.