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ONTOLOGY REPORT - ANNOTATIONS


Term:induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration
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Accession:GO:0099703 term browser browse the term
Definition:The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.


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induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1b calcium voltage-gated channel subunit alpha1 B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:37,950,846...38,211,478
Ensembl chr 3:37,955,069...38,090,526
JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cnr1 cannabinoid receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:152,087,393...152,380,023
Ensembl chr 4:152,087,379...152,380,184
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      regulation of signaling 3517
        regulation of trans-synaptic signaling 652
          modulation of chemical synaptic transmission 651
            presynaptic modulation of chemical synaptic transmission 19
              induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration 7
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological quality 4175
        homeostatic process 1988
          chemical homeostasis 1353
            ion homeostasis 870
              cellular ion homeostasis 739
                cellular cation homeostasis 723
                  cellular metal ion homeostasis 656
                    cellular calcium ion homeostasis 516
                      regulation of cytosolic calcium ion concentration 414
                        positive regulation of cytosolic calcium ion concentration 363
                          positive regulation of presynaptic cytosolic calcium concentration 7
                            induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration 7
paths to the root