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ONTOLOGY REPORT - ANNOTATIONS

Term:ventricular cardiac muscle cell membrane repolarization
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Accession:GO:0099625 term browser browse the term
Definition:The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.


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ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in ISO (PMID:21349352) RGD PMID:21349352 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 involved_in ISO (PMID:20558321) RGD PMID:20558321 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:8528244)
GO_REF:0000107
MGI:2680653 (MGI:3587563|PMID:15004216), (MGI:3719729|PMID:12766260)
PMID:21873635		 RGD
Ensembl		 PMID:8528244 PMID:12766260 PMID:15004216 PMID:21873635 GO_REF:0000107 MGI:3587563 MGI:3719729, RGD:13792537 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) RGD PMID:22987075 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
regulation of ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in IBA
ISO		 PMID:21873635
(PMID:18093912)		 RGD PMID:18093912 PMID:21873635 RGD:13792537 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Ank2 ankyrin 2 involved_in ISO (PMID:18832177) RGD PMID:18832177 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA		 (PMID:25527503)
GO_REF:0000107		 RGD
Ensembl		 PMID:25527503 GO_REF:0000107 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177|MGI:95716 (MGI:3639795|PMID:10969038) RGD PMID:10969038 MGI:3639795 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445238|MGI:95713 (MGI:3639795|PMID:10969038)
(MGI:6101691|PMID:26786475)		 RGD PMID:10969038 PMID:26786475 MGI:3639795 MGI:6101691 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO
IBA		 (PMID:9354802)
PMID:21873635		 RGD PMID:9354802 PMID:21873635 RGD:13792537 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3699589 (MGI:3813163|PMID:18603586)
(PMID:10219239)		 RGD PMID:10219239 PMID:18603586 PMID:21873635 MGI:3813163, RGD:13792537 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO
IBA		 (PMID:21493962)
PMID:21873635		 RGD PMID:21493962 PMID:21873635 RGD:13792537 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:21536673)
PMID:21873635
(MGI:1860395|PMID:10843886)		 RGD PMID:10843886 PMID:21536673 PMID:21873635 MGI:1860395, RGD:13792537 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA		 (PMID:8528244)
GO_REF:0000107
MGI:2680653 (MGI:1931646|PMID:11226272)		 RGD
Ensembl		 PMID:8528244 PMID:11226272 GO_REF:0000107 MGI:1931646 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein involved_in ISO (PMID:19247217) RGD PMID:19247217 NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA		 (MGI:3763979|PMID:17884088)
GO_REF:0000107		 RGD
Ensembl		 PMID:17884088 GO_REF:0000107 MGI:3763979 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO
IBA		 (PMID:17592081)
PMID:21873635		 RGD PMID:17592081 PMID:21873635 RGD:13792537 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:7889574)		 BHF-UCL
Ensembl
RGD		 PMID:7889574 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Snta1 syntrophin, alpha 1 involved_in ISO (PMID:18591664) RGD PMID:18591664 NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709 		JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO (MGI:5574550|PMID:24840128) RGD PMID:24840128 MGI:5574550 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:5824440|PMID:27799555) RGD PMID:27799555 MGI:5824440 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    biological regulation 13187
      regulation of biological quality 3248
        regulation of membrane potential 517
          membrane repolarization 55
            cardiac muscle cell membrane repolarization 35
              ventricular cardiac muscle cell membrane repolarization 24
                membrane repolarization during ventricular cardiac muscle cell action potential + 10
                regulation of ventricular cardiac muscle cell membrane repolarization + 21
paths to the root