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ONTOLOGY REPORT - ANNOTATIONS

Term:ventricular cardiac muscle cell membrane repolarization
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Accession:GO:0099625 term browser browse the term
Definition:The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.


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ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IMP (PMID:21349352) BHF-UCL PMID:21349352 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163 		JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP (PMID:9354802) BHF-UCL PMID:9354802 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729 		JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,052,190...223,198,399 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IMP (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA GOC GO_REF:0000108 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in IMP (PMID:20558321) BHF-UCL PMID:20558321 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO
IMP		 (PMID:21873635)
(MGI:3587563|PMID:15004216), (MGI:3719729|PMID:12766260)
(PMID:8528244)		 GO_Central
Ensembl
MGI
BHF-UCL		 PMID:8528244 PMID:12766260 PMID:15004216 PMID:21873635 GO_REF:0000107 MGI:3587563 MGI:3719729 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA GOC GO_REF:0000108 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639 		JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IMP (PMID:22987075) BHF-UCL PMID:22987075 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729 		JBrowse link
regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR133A1 microRNA 133a-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr18:21,825,698...21,825,785
Ensembl chr18:21,825,698...21,825,785 		JBrowse link
G MIR133A2 microRNA 133a-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr20:62,564,912...62,565,013
Ensembl chr20:62,564,912...62,565,013 		JBrowse link
regulation of ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 involved_in IBA
IMP		 (PMID:21873635)
(PMID:18093912)		 GO_Central
BHF-UCL		 PMID:18093912 PMID:21873635 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673 		JBrowse link
G ANK2 ankyrin 2 involved_in IMP (PMID:18832177) BHF-UCL PMID:18832177 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IMP (PMID:25527503) BHF-UCL PMID:25527503 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956 		JBrowse link
G CAV3 caveolin 3 involved_in IMP (PMID:17060380) BHF-UCL PMID:17060380 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808 		JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3639795|PMID:10969038) MGI
Ensembl		 PMID:10969038 GO_REF:0000107 MGI:3639795 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO
ISS		 (MGI:3639795|PMID:10969038) MGI
BHF-UCL		 PMID:10969038 GO_REF:0000024 MGI:3639795 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP
IBA		 (PMID:9354802)
(PMID:21873635)		 BHF-UCL
GO_Central		 PMID:9354802 PMID:21873635 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IMP		 (MGI:3813163|PMID:18603586)
(PMID:21873635)
(PMID:10219239)		 MGI
GO_Central
BHF-UCL		 PMID:10219239 PMID:18603586 PMID:21873635 MGI:3813163 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729 		JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,052,190...223,198,399 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IMP
IBA		 (PMID:21493962)
(PMID:21873635)		 BHF-UCL
GO_Central		 PMID:21493962 PMID:21873635 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IMP		 (MGI:1860395|PMID:10843886)
(PMID:21873635)
(PMID:21536673)		 MGI
GO_Central
BHF-UCL		 PMID:10843886 PMID:21536673 PMID:21873635 MGI:1860395 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:63,523,358...63,548,992
Ensembl chr17:63,523,334...63,548,977 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP
IEA		 (PMID:8528244) BHF-UCL
Ensembl		 PMID:8528244 GO_REF:0000107 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G MIR133A1 microRNA 133a-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr18:21,825,698...21,825,785
Ensembl chr18:21,825,698...21,825,785 		JBrowse link
G MIR133A2 microRNA 133a-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr20:62,564,912...62,565,013
Ensembl chr20:62,564,912...62,565,013 		JBrowse link
G NOS1AP nitric oxide synthase 1 adaptor protein involved_in ISS
IMP		 (PMID:18337493)
(PMID:19247217)		 BHF-UCL PMID:18337493 PMID:19247217 NCBI chr 1:162,069,691...162,370,475
Ensembl chr 1:162,069,691...162,370,475 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in ISS
IEA		 (PMID:17884088) BHF-UCL
Ensembl		 PMID:17884088 GO_REF:0000107 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IBA
IMP		 (PMID:21873635)
(PMID:17592081)		 GO_Central
BHF-UCL		 PMID:17592081 PMID:21873635 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:7889574) BHF-UCL PMID:7889574 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687 		JBrowse link
G SNTA1 syntrophin alpha 1 involved_in IMP (PMID:18591664) BHF-UCL PMID:18591664 NCBI chr20:33,407,957...33,443,763
Ensembl chr20:33,407,957...33,443,763 		JBrowse link
G WDR1 WD repeat domain 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5574550|PMID:24840128) MGI
Ensembl		 PMID:24840128 GO_REF:0000107 MGI:5574550 NCBI chr 4:10,074,339...10,116,799
Ensembl chr 4:10,068,089...10,116,972 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5824440|PMID:27799555) MGI
Ensembl		 PMID:27799555 GO_REF:0000107 MGI:5824440 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19567
    biological regulation 13270
      regulation of biological quality 3435
        regulation of membrane potential 543
          membrane repolarization 58
            cardiac muscle cell membrane repolarization 41
              ventricular cardiac muscle cell membrane repolarization 28
                membrane repolarization during ventricular cardiac muscle cell action potential + 14
                regulation of ventricular cardiac muscle cell membrane repolarization + 23
paths to the root