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ONTOLOGY REPORT - ANNOTATIONS


Term:ventricular cardiac muscle cell membrane repolarization
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Accession:GO:0099625 term browser browse the term
Definition:The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.


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ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in ISO (PMID:21349352) RGD PMID:21349352 NCBI chr 2:192,937,950...193,155,345 JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:192,937,950...193,155,345 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:31,580,951...31,594,116 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:31,517,176...31,530,026 JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:154,523,903...154,530,865 JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:80,243,429...80,251,533 JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:105,930,398...105,931,013 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:21536673)
Ensembl
RGD
PMID:21536673 GO_REF:0000107 NCBI chr 4:10,826,834...10,859,009 JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 involved_in ISO (PMID:20558321) RGD PMID:20558321 NCBI chr 4:175,508,908...175,515,829 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IBA
IEA
(PMID:8528244)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8528244, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:198,291,711...198,624,683 JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) RGD PMID:22987075 NCBI chr 1:154,523,903...154,530,865 JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in ISO (PMID:25281747) RGD PMID:25281747 NCBI chr 5:162,815,351...162,828,325 JBrowse link
regulation of ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in IBA
ISO
PMID:21873635
(PMID:18093912)
RGD PMID:18093912, PMID:21873635 RGD:13792537 NCBI chr 4:30,056,738...30,192,716 JBrowse link
G Ank2 ankyrin 2 involved_in ISO (PMID:18832177) RGD PMID:18832177 NCBI chr 2:215,378,028...215,954,015 JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA
(PMID:25527503)
GO_REF:0000107
RGD
Ensembl
PMID:25527503 GO_REF:0000107 NCBI chr 4:18,950,611...19,374,969 JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:145,582,168...145,598,142 JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177|MGI:95716 (MGI:3639795|PMID:10969038) RGD PMID:10969038 MGI:3639795 NCBI chr20:35,756,007...35,768,481 JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445238|MGI:95713 (MGI:3639795|PMID:10969038)
(MGI:6101691|PMID:26786475)
RGD PMID:10969038 PMID:26786475 MGI:3639795 MGI:6101691 NCBI chr 2:184,602,407...184,621,952 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO
IBA
(PMID:9354802)
PMID:21873635
RGD PMID:9354802, PMID:21873635 RGD:13792537 NCBI chr11:31,580,951...31,594,116 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3699589 (MGI:3813163|PMID:18603586)
(PMID:10219239)
RGD PMID:10219239 PMID:18603586, PMID:21873635 MGI:3813163, RGD:13792537 NCBI chr11:31,517,176...31,530,026 JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:154,523,903...154,530,865 JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:80,243,429...80,251,533 JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO
IBA
(PMID:21493962)
PMID:21873635
RGD PMID:21493962, PMID:21873635 RGD:13792537 NCBI chr  X:105,930,398...105,931,013 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1860395|PMID:10843886)
(PMID:21536673)
Ensembl
RGD
PMID:10843886 PMID:21536673 GO_REF:0000107 MGI:1860395 NCBI chr 4:10,826,834...10,859,009 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:8528244)
GO_REF:0000107
MGI:2680653 (MGI:1931646|PMID:11226272)
RGD
Ensembl
PMID:8528244 PMID:11226272 GO_REF:0000107 MGI:1931646 NCBI chr 1:198,291,711...198,624,683 JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein involved_in ISO (PMID:19247217) RGD PMID:19247217 NCBI chr13:82,549,786...82,820,949 JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO (MGI:3763979|PMID:17884088) RGD PMID:17884088 MGI:3763979 NCBI chr 1:86,353,917...86,363,836 JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO
IBA
(PMID:17592081)
PMID:21873635
RGD PMID:17592081, PMID:21873635 RGD:13792537 NCBI chr 8:45,446,580...45,462,294 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:7889574)
BHF-UCL
Ensembl
RGD
PMID:7889574 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816 JBrowse link
G Snta1 syntrophin, alpha 1 involved_in ISO (PMID:18591664) RGD PMID:18591664 NCBI chr 3:142,876,285...142,906,737 JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO (MGI:5574550|PMID:24840128) RGD PMID:24840128 MGI:5574550 NCBI chr14:72,258,032...72,291,768 JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:5824440|PMID:27799555) RGD PMID:27799555 MGI:5824440 NCBI chr 5:134,627,218...134,660,360 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      cellular localization 2989
        establishment of localization in cell 2183
          cardiac muscle cell membrane repolarization 30
            ventricular cardiac muscle cell membrane repolarization 23
              membrane repolarization during ventricular cardiac muscle cell action potential + 10
              regulation of ventricular cardiac muscle cell membrane repolarization + 21
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6444
      establishment of localization 4863
        transport 4699
          ion transport 1638
            ion transmembrane transport 1138
              membrane repolarization 43
                cardiac muscle cell membrane repolarization 30
                  ventricular cardiac muscle cell membrane repolarization 23
                    membrane repolarization during ventricular cardiac muscle cell action potential + 10
                    regulation of ventricular cardiac muscle cell membrane repolarization + 21
paths to the root