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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac muscle cell membrane repolarization
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Accession:GO:0099622 term browser browse the term
Definition:The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
Synonyms:only_in_taxon: NCBITaxon:33208 ! Metazoa


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membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,439,336...65,442,207
Ensembl chr 5:65,439,336...65,442,207 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,836,777...55,861,288
Ensembl chr 9:55,836,701...55,864,941 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:5292192 NCBI chr 2:118,439,328...118,882,299
Ensembl chr 2:118,439,403...118,882,295 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,439,336...65,442,207
Ensembl chr 5:65,439,336...65,442,207 		JBrowse link
membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,741,190...89,742,672 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:10,351,959...10,380,631
Ensembl chr12:10,351,699...10,362,244 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,439,336...65,442,207
Ensembl chr 5:65,439,336...65,442,207 		JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 4:108,394,687...108,621,514
Ensembl chr 4:108,246,237...108,621,510 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:197,979,749...197,980,974
Ensembl chr13:197,980,145...197,980,516 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,720...8,822,494 		JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GOC GO_REF:0000108 NCBI chr15:124,910,708...124,915,787
Ensembl chr15:124,912,406...124,915,780 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,741,190...89,742,672 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:51,695,927...51,704,402
Ensembl chr 5:51,696,188...51,703,813 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3587563|PMID:15004216), (MGI:3719729|PMID:12766260) MGI
Ensembl		 PMID:12766260 PMID:15004216 GO_REF:0000107 MGI:3587563 MGI:3719729 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:45,484,994...45,502,578
Ensembl chr 9:45,484,998...45,498,465 		JBrowse link
negative regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR1 microRNA mir-1 involved_in ISO (PMID:23157812) BHF-UCL PMID:23157812 NCBI chr17:61,894,036...61,894,143
Ensembl chr17:61,894,036...61,894,143 		JBrowse link
G MIR133A-1 microRNA mir-133a-1 involved_in ISO (PMID:23157812) BHF-UCL PMID:23157812 NCBI chr17:61,904,781...61,904,883
Ensembl chr17:61,904,781...61,904,883 		JBrowse link
G MIR133A-2 microRNA mir-133a-2 involved_in ISO (PMID:23157812) BHF-UCL PMID:23157812 NCBI chr 6:106,998,899...106,998,971
Ensembl chr 6:106,998,896...106,998,982 		JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,720...8,822,494 		JBrowse link
regulation of atrial cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in ISO (MGI:3771286|PMID:17110593) BHF-UCL PMID:17110593 MGI:3771286 NCBI chr13:35,568,534...35,911,483
Ensembl chr13:35,436,519...35,909,662 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,439,336...65,442,207
Ensembl chr 5:65,439,336...65,442,207 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,741,190...89,742,672 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
G NPPA natriuretic peptide A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,918,845...71,921,405 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,336,143...23,424,755
Ensembl chr13:23,336,153...23,424,755 		JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A involved_in ISO (MGI:5578267|PMID:24951510) BHF-UCL PMID:24951510 MGI:5578267 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,162...124,914,992 		JBrowse link
regulation of ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 9:71,895,615...72,054,898
Ensembl chr 9:71,895,635...72,054,897 		JBrowse link
G ANK2 ankyrin 2 involved_in ISO (PMID:18832177) BHF-UCL PMID:18832177 NCBI chr 8:109,306,793...109,661,970 JBrowse link
G C4H1orf226 chromosome 4 C1orf226 homolog involved_in ISO (PMID:19247217) BHF-UCL PMID:19247217 NCBI chr 4:88,129,231...88,471,741
Ensembl chr 4:88,140,953...88,471,994 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:97,781,057...98,265,925
Ensembl chr 9:97,781,090...98,266,969 		JBrowse link
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:65,117,868...65,130,886
Ensembl chr13:65,117,795...65,131,273 		JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:36,917,276...36,946,232
Ensembl chr17:36,915,953...36,946,187 		JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3639795|PMID:10969038) MGI
Ensembl		 PMID:10969038 GO_REF:0000107 MGI:3639795 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156 		JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:3639795|PMID:10969038)
(MGI:6101691|PMID:26786475)		 MGI
BHF-UCL		 PMID:10969038 PMID:26786475 MGI:3639795 MGI:6101691 NCBI chr 4:99,854,129...99,871,288
Ensembl chr 4:99,854,392...99,871,286 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3813163|PMID:18603586) MGI
Ensembl		 PMID:18603586 GO_REF:0000107 MGI:3813163 NCBI chr13:197,979,749...197,980,974
Ensembl chr13:197,980,145...197,980,516 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,720...8,822,494 		JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:124,910,708...124,915,787
Ensembl chr15:124,912,406...124,915,780 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,741,190...89,742,672 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1860395|PMID:10843886) MGI
Ensembl		 PMID:10843886 GO_REF:0000107 MGI:1860395 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:15,352,765...15,374,763
Ensembl chr12:15,353,867...15,374,858 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,597,461...44,607,488
Ensembl chr 6:44,597,482...44,607,481 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:45,451,473...45,475,606 JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,336,143...23,424,755
Ensembl chr13:23,336,153...23,424,755 		JBrowse link
G WDR1 WD repeat domain 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5574550|PMID:24840128) MGI
Ensembl		 PMID:24840128 GO_REF:0000107 MGI:5574550 NCBI chr 8:6,413,338...6,452,383
Ensembl chr 8:6,413,347...6,452,346 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5824440|PMID:27799555) MGI
Ensembl		 PMID:27799555 GO_REF:0000107 MGI:5824440 NCBI chr 6:96,008,307...96,057,131
Ensembl chr 6:96,008,455...96,062,951 		JBrowse link
ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:108,394,687...108,621,514
Ensembl chr 4:108,246,237...108,621,510 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17412
    biological regulation 12515
      regulation of biological quality 3060
        regulation of membrane potential 510
          membrane repolarization 54
            cardiac muscle cell membrane repolarization 34
              atrial cardiac muscle cell membrane repolarization + 8
              membrane repolarization during cardiac muscle cell action potential + 18
              regulation of cardiac muscle cell membrane repolarization + 28
              ventricular cardiac muscle cell membrane repolarization + 24
paths to the root