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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac muscle cell membrane repolarization
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Accession:GO:0099622 term browser browse the term
Definition:The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
Synonyms:only_in_taxon: NCBITaxon:33208 ! Metazoa


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membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,165,057...5,168,307 JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:123,705,361...123,735,370
Ensembl chr11:127,606,208...127,634,213 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:5292192 NCBI chr 5:109,722,916...109,862,747
Ensembl chr 5:115,522,443...115,661,079 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chr11:2,469,750...2,874,467 JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:23264583) BHF-UCL PMID:23264583 NCBI chr12:5,165,057...5,168,307 JBrowse link
membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:20,818,395...20,884,053
Ensembl chr21:34,190,043...34,190,441 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:98,731,109...98,732,575
Ensembl chr  X:109,202,320...109,202,748 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:142,528,979...142,562,074 JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,469,750...2,874,467 JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045) BHF-UCL PMID:19343045 NCBI chr12:5,165,057...5,168,307 JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:114,433,203...114,651,894
Ensembl chr 1:125,696,907...125,909,814 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:20,818,395...20,884,053
Ensembl chr21:34,190,043...34,190,441 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:142,528,979...142,562,074 JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,522,172...64,532,848
Ensembl chr12:67,127,263...67,137,128 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12766260), (PMID:15004216) Ensembl
MGI		 PMID:12766260 PMID:15004216 GO_REF:0000107 NCBI chr11:2,469,750...2,874,467 JBrowse link
G LOC106634235 uncharacterized LOC106634235 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA GOC GO_REF:0000108 NCBI chr11:112,996,609...113,010,412
Ensembl chr11:116,928,676...116,942,500 		JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:69,527,663...69,540,236
Ensembl chr11:72,835,048...72,835,359 		JBrowse link
regulation of atrial cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in ISO (MGI:3771286|PMID:17110593) BHF-UCL PMID:17110593 MGI:3771286 NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045) BHF-UCL PMID:19343045 NCBI chr12:5,165,057...5,168,307 JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:98,731,109...98,732,575
Ensembl chr  X:109,202,320...109,202,748 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251) BHF-UCL PMID:12522251 NCBI chr11:2,469,750...2,874,467 JBrowse link
G NPPA natriuretic peptide A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A involved_in ISO (MGI:5578267|PMID:24951510) BHF-UCL PMID:24951510 MGI:5578267 NCBI chr  X:143,799,088...143,825,282 JBrowse link
regulation of ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:83,942,590...84,108,648
Ensembl chr 7:97,540,356...97,705,608 		JBrowse link
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:73,917,439...74,410,627
Ensembl chr 7:87,579,004...88,068,482 		JBrowse link
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:10969038) MGI PMID:10969038 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of
acts_upstream_of_or_within		 ISO (MGI:6101691|PMID:26786475)
(PMID:10969038)		 BHF-UCL
MGI		 PMID:10969038 PMID:26786475 MGI:6101691 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:20,818,395...20,884,053
Ensembl chr21:34,190,043...34,190,441 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:69,527,663...69,540,236
Ensembl chr11:72,835,048...72,835,359 		JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:110,291,194...110,294,996
Ensembl chr2B:228,869,393...228,873,101 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:98,731,109...98,732,575
Ensembl chr  X:109,202,320...109,202,748 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10843886) TreeGrafter
MGI		 PMID:10843886 GO_REF:0000118 NCBI chr 7:142,528,979...142,562,074 JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:57,603,039...57,626,964
Ensembl chr17:62,749,216...62,772,544 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,469,750...2,874,467 JBrowse link
G LOC100983469 carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:137,487,845...137,800,242
Ensembl chr 1:141,285,960...141,578,899 		JBrowse link
G LOC106634235 uncharacterized LOC106634235 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18603586) Ensembl
MGI
TreeGrafter		 PMID:18603586 GO_REF:0000107 GO_REF:0000118 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:112,967,190...112,986,727
Ensembl chr11:116,899,268...116,918,892 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
G SNTA1 syntrophin alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:29,696,137...29,732,258
Ensembl chr20:30,810,787...30,844,476 		JBrowse link
G WDR1 WD repeat domain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24840128) Ensembl
MGI		 PMID:24840128 GO_REF:0000107 NCBI chr 4:4,487,054...4,516,732
Ensembl chr 4:9,805,164...9,848,032 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27799555) Ensembl
MGI		 PMID:27799555 GO_REF:0000107 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747 		JBrowse link
ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,433,203...114,651,894
Ensembl chr 1:125,696,907...125,909,814 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological quality 3071
        regulation of membrane potential 510
          membrane repolarization 49
            cardiac muscle cell membrane repolarization 32
              atrial cardiac muscle cell membrane repolarization + 8
              membrane repolarization during cardiac muscle cell action potential + 15
              regulation of cardiac muscle cell membrane repolarization + 26
              ventricular cardiac muscle cell membrane repolarization + 25
paths to the root