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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle cell membrane repolarization
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Accession:GO:0099622 term browser browse the term
Definition:The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
Synonyms:only_in_taxon: NCBITaxon:33208 ! Metazoa



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membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) RGD PMID:19343045 PMID:23264583 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 involved_in ISO
IEA
(PMID:20560207)
GO_REF:0000107
RGD
Ensembl
PMID:20560207 GO_REF:0000107 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040)
(PMID:19139040)
RGD PMID:19139040 MGI:5292192 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:12522251), (PMID:25786344)
GO_REF:0000107
RGD
Ensembl
PMID:12522251 PMID:25786344 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:23264583) RGD PMID:23264583 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:10400998), (PMID:8900283) RGD PMID:8900283 PMID:10400998 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO
IBA
(PMID:21536673)
GO_REF:0000033
RGD
GO_Central
PMID:21536673 GO_REF:0000033 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 involved_in ISO (PMID:11371347) RGD PMID:11371347 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) RGD PMID:8528244 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045) RGD PMID:19343045 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25447080)
Ensembl
RGD
PMID:25447080 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 involved_in ISO (PMID:20558321) RGD PMID:20558321 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
(PMID:8528244)
MGI:2680653 (PMID:12766260), (PMID:15004216)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:8528244 PMID:12766260 PMID:15004216 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765
JBrowse link
negative regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir1 microRNA 1 involved_in ISO (PMID:23157812) RGD PMID:23157812 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:23157812) RGD PMID:23157812 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir1b microRNA 1b involved_in ISO (PMID:23157812) RGD PMID:23157812 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201
JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:23157812) RGD PMID:23157812 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) RGD PMID:22987075 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:25281747)
Ensembl
RGD
PMID:25281747 GO_REF:0000107 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375
JBrowse link
regulation of atrial cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in ISO (MGI:3771286|PMID:17110593) RGD PMID:17110593 MGI:3771286 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045) RGD PMID:19343045 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) RGD PMID:18313602 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:12522251)
GO_REF:0000107
RGD
Ensembl
PMID:12522251 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Nppa natriuretic peptide A involved_in ISO
IEA
(PMID:19646991)
GO_REF:0000107
RGD
Ensembl
PMID:19646991 GO_REF:0000107 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
ISS
(PMID:19167345)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:19167345 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flna filamin A involved_in ISO (MGI:5578267|PMID:24951510)
(PMID:24951510)
RGD PMID:24951510 MGI:5578267 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
regulation of ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in ISO
IBA
(PMID:18093912)
GO_REF:0000033
RGD
GO_Central
PMID:18093912 GO_REF:0000033 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Ank2 ankyrin 2 involved_in ISO (PMID:18832177) RGD PMID:18832177 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA
(PMID:25527503)
GO_REF:0000107
RGD
Ensembl
PMID:25527503 GO_REF:0000107 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177|MGI:95716 (PMID:10969038) RGD PMID:10969038 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of
acts_upstream_of_or_within
ISO (MGI:6101691|PMID:26786475)
(PMID:26786475)
MGI:2445238|MGI:95713 (PMID:10969038)
RGD PMID:10969038 PMID:26786475 MGI:6101691 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO
IBA
(PMID:9354802)
GO_REF:0000033
RGD
GO_Central
PMID:9354802 GO_REF:0000033 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:10219239)
MGI:3699589 (PMID:18603586)
GO_REF:0000033
RGD
GO_Central
PMID:10219239 PMID:18603586 GO_REF:0000033 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO
IBA
(PMID:21493962)
GO_REF:0000033
RGD
GO_Central
PMID:21493962 GO_REF:0000033 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21536673)
(PMID:10843886)
GO_REF:0000033
RGD
GO_Central
PMID:10843886 PMID:21536673 GO_REF:0000033 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:8528244)
MGI:2680653 (PMID:11226272)
GO_REF:0000107
RGD
Ensembl
PMID:8528244 PMID:11226272 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein involved_in ISO (PMID:19247217) RGD PMID:19247217 NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA
(MGI:3763979|PMID:17884088)
(PMID:17884088)
GO_REF:0000107
RGD
Ensembl
PMID:17884088 GO_REF:0000107 MGI:3763979 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO
IBA
(PMID:17592081)
GO_REF:0000033
RGD
GO_Central
PMID:17592081 GO_REF:0000033 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:7889574)
BHF-UCL
Ensembl
RGD
PMID:7889574 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Snta1 syntrophin, alpha 1 involved_in ISO (PMID:18591664) RGD PMID:18591664 NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709
JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO (PMID:24840128) RGD PMID:24840128 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (PMID:27799555) RGD PMID:27799555 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
ventricular cardiac muscle cell membrane repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in ISO (PMID:21349352) RGD PMID:21349352 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    biological regulation 13566
      regulation of biological quality 3390
        regulation of membrane potential 548
          membrane repolarization 56
            cardiac muscle cell membrane repolarization 37
              atrial cardiac muscle cell membrane repolarization + 8
              membrane repolarization during cardiac muscle cell action potential + 22
              regulation of cardiac muscle cell membrane repolarization + 30
              ventricular cardiac muscle cell membrane repolarization + 26
paths to the root