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ONTOLOGY REPORT - ANNOTATIONS

Term:maintenance of synapse structure
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Accession:GO:0099558 term browser browse the term
Definition:A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.
Synonyms:exact_synonym: synaptic maintenance


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maintenance of synapse structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb3 adhesion G protein-coupled receptor B3 acts_upstream_of_or_within ISO MGI:5708584 (PMID:25611509) RGD PMID:25611509 NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21236345) RGD PMID:21236345 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G C1ql1 complement C1q like 1 acts_upstream_of_or_within ISO MGI:5708580 (PMID:25611509) RGD PMID:25611509 NCBI chr10:87,902,125...87,909,556
Ensembl chr10:87,902,137...87,909,310 		JBrowse link
G Cbln1 cerebellin 1 precursor involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:6158264|PMID:29691328)		 UniProt
GO_Central
RGD		 PMID:29691328 GO_REF:0000024 GO_REF:0000033 MGI:6158264 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
G Cbln2 cerebellin 2 precursor involved_in ISO
IBA
ISS		 (MGI:6158264|PMID:29691328)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:29691328 GO_REF:0000024 GO_REF:0000033 MGI:6158264 NCBI chr18:79,940,412...79,948,766
Ensembl chr18:79,942,590...79,947,855 		JBrowse link
G Cbln3 cerebellin 3 precursor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:29,362,014...29,364,523
Ensembl chr15:29,362,302...29,364,612 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (MGI:5920587|PMID:28585542) RGD PMID:28585542 MGI:5920587 NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (PMID:25951243), (PMID:31141683) RGD PMID:25951243 PMID:31141683 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Grn granulin precursor involved_in ISO (PMID:29398357) RGD PMID:29398357 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G L1cam L1 cell adhesion molecule involved_in ISO (PMID:30846310) RGD PMID:30846310 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Nlgn1 neuroligin 1 involved_in NAS PMID:29504935 ComplexPortal PMID:29504935 RGD:151356619 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nrxn1 neurexin 1 involved_in NAS PMID:29504935 ComplexPortal PMID:29504935 RGD:151356619 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Plxna4 plexin A4 involved_in ISO (PMID:24831527) RGD PMID:24831527 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206 		JBrowse link
G Sdf4 stromal cell derived factor 4 involved_in ISO FB:FBgn0051475 (PMID:33667157) RGD PMID:33667157 NCBI chr 5:166,586,581...166,606,661
Ensembl chr 5:166,586,390...166,604,521 		JBrowse link
G Sema3a semaphorin 3A involved_in ISO (PMID:24831527) RGD PMID:24831527 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Sort1 sortilin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29398357)		 Ensembl
RGD		 PMID:29398357 GO_REF:0000107 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
maintenance of postsynaptic density structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 involved_in IDA
IMP		 PMID:16672654 SynGO PMID:16672654 PMID:16672654 RGD:8554141, RGD:8554141 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114 		JBrowse link
G Csmd2 CUB and Sushi multiple domains 2 involved_in ISO (PMID:31068362) RGD PMID:31068362 NCBI chr 5:140,342,352...140,912,422
Ensembl chr 5:140,342,376...140,912,234 		JBrowse link
G Ctnnd2 catenin delta 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (PMID:19229292) RGD PMID:19229292 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 acts_upstream_of_or_within ISO (MGI:3716052|PMID:17046693) RGD PMID:17046693 MGI:3716052 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlgap1 DLG associated protein 1 involved_in IC GO_REF:0000036 SynGO GO_REF:0000036 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240 		JBrowse link
G Mpp2 MAGUK p55 scaffold protein 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:87,011,434...87,043,883
Ensembl chr10:87,011,434...87,043,896 		JBrowse link
G Ppfia2 PTPRF interacting protein alpha 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:41,765,716...42,240,104
Ensembl chr 7:41,765,575...42,239,599 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO (PMID:34613779) RGD PMID:34613779 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prickle2 prickle planar cell polarity protein 2 involved_in ISO (PMID:34613779) RGD PMID:34613779 NCBI chr 4:124,869,655...125,214,862
Ensembl chr 4:124,869,552...125,214,824 		JBrowse link
G Psd pleckstrin and Sec7 domain containing involved_in IDA
IMP		 PMID:16672654 SynGO PMID:16672654 PMID:16672654 RGD:8554141, RGD:8554141 NCBI chr 1:245,173,279...245,188,681
Ensembl chr 1:245,173,279...245,189,356 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 involved_in IC GO_REF:0000036 SynGO GO_REF:0000036 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in IC
IEA		 GO_REF:0000036
GO_REF:0000108		 SynGO
GOC		 GO_REF:0000036 GO_REF:0000108 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:90,553,124...90,873,477
Ensembl chr10:90,553,002...90,868,756 		JBrowse link
maintenance of postsynaptic specialization structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrl3 adhesion G protein-coupled receptor L3 involved_in ISO (PMID:30792275) RGD PMID:30792275 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860 		JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO (PMID:21145003) RGD PMID:21145003 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in EXP
IMP
IDA		 PMID:21209184 SynGO PMID:21209184 PMID:21209184 PMID:21209184 RGD:13702189, RGD:13702189, RGD:13702189 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in EXP
IDA		 PMID:20935643 SynGO PMID:20935643 PMID:20935643 RGD:155230798, RGD:155230798 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in IDA
EXP		 PMID:20935643 SynGO PMID:20935643 PMID:20935643 RGD:155230798, RGD:155230798 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Ophn1 oligophrenin 1 involved_in EXP
IMP
IDA		 PMID:24966368 SynGO PMID:24966368 PMID:24966368 PMID:24966368 RGD:13702374, RGD:13702374, RGD:13702374 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:27565345)		 Ensembl
RGD		 PMID:27565345 GO_REF:0000107 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672 		JBrowse link
maintenance of presynaptic active zone structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bsn bassoon (presynaptic cytomatrix protein) involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
(MGI:6189424|PMID:26793095)		 GOC
RGD		 PMID:26793095 GO_REF:0000108 MGI:6189424 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819 		JBrowse link
G Ctbp2 C-terminal binding protein 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639 		JBrowse link
G Erc2 ELKS/RAB6-interacting/CAST family member 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:6189473|PMID:27537483)
GO_REF:0000033
GO_REF:0000108		 RGD
GO_Central
GOC		 PMID:27537483 GO_REF:0000033 GO_REF:0000108 MGI:6189473 NCBI chr16:2,812,712...3,673,624
Ensembl chr16:2,848,620...3,670,776 		JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3762127 (PMID:11359932)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:11359932 GO_REF:0000033 GO_REF:0000107 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Rimbp2 RIMS binding protein 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:27,747,615...27,946,256
Ensembl chr12:27,747,980...27,956,763 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 acts_upstream_of_or_within ISO (MGI:6189473|PMID:27537483) RGD PMID:27537483 MGI:6189473 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular component organization or biogenesis 7290
        cellular component organization 6980
          cell junction organization 998
            cell junction maintenance 80
              maintenance of synapse structure 52
                maintenance of alignment of postsynaptic density and presynaptic active zone 0
                maintenance of postsynaptic specialization structure + 27
                maintenance of presynaptic active zone structure 9
paths to the root