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ONTOLOGY REPORT - ANNOTATIONS


Term:presynaptic dense core vesicle exocytosis
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Accession:GO:0099525 term browser browse the term
Definition:The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.



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presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q8BYR5 (MGI:5634021|PMID:25719439)
Ensembl
RGD
PMID:25719439 GO_REF:0000107 MGI:5634021 NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779
JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) RGD PMID:11545717 MGI:3621672 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Syt6 synaptotagmin 6 involved_in IMP
IDA
PMID:26216953 SynGO PMID:26216953 PMID:26216953 RGD:13702162, RGD:13702162 NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956
JBrowse link
G Unc13a unc-13 homolog A involved_in IBA
ISO
PMID:21873635
UniProtKB:Q9Z1N9 (MGI:5819330|PMID:26575293)
RGD PMID:26575293 PMID:21873635 MGI:5819330, RGD:13792537 NCBI chr16:18,336,229...18,381,811
Ensembl chr16:18,336,229...18,381,872
JBrowse link
G Unc13b unc-13 homolog B involved_in IBA
ISO
PMID:21873635
(MGI:5819330|PMID:26575293)
RGD PMID:26575293 PMID:21873635 MGI:5819330, RGD:13792537 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926
JBrowse link
G Unc13c unc-13 homolog C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223
JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in EXP
IDA
PMID:24037803 SynGO PMID:24037803 PMID:24037803 RGD:13702177, RGD:13702177 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:4457852|PMID:19448629) RGD PMID:19448629 MGI:4457852 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      cellular localization 3075
        establishment of localization in cell 2295
          synaptic vesicle exocytosis 154
            calcium ion-regulated exocytosis of neurotransmitter 22
              presynaptic dense core vesicle exocytosis 8
                neuropeptide secretion from presynapse 0
                regulation of presynaptic dense core granule exocytosis 2
Path 2
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      establishment of localization 4941
        transport 4779
          export from cell 1033
            secretion by cell 978
              exocytosis 427
                regulated exocytosis 295
                  calcium-ion regulated exocytosis 78
                    dense core granule exocytosis 11
                      neuronal dense core vesicle exocytosis 8
                        presynaptic dense core vesicle exocytosis 8
                          neuropeptide secretion from presynapse 0
                          regulation of presynaptic dense core granule exocytosis 2
paths to the root