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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-dependent activation of synaptic vesicle fusion
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Accession:GO:0099502 term browser browse the term
Definition:The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.


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calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prrt2 proline rich transmembrane protein 2 ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 NCBI chrNW_004936501:12,660,181...12,663,788 JBrowse link
G Syt1 synaptotagmin 1 ISO (MGI:69538|PMID:7954835) SynGO PMID:7954835 MGI:69538 NCBI chrNW_004936698:65,210...575,538 JBrowse link
G Syt2 synaptotagmin 2 ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chrNW_004936567:1,941,651...1,984,422 JBrowse link
G Syt7 synaptotagmin 7 ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chrNW_004936581:1,516,199...1,557,992 JBrowse link
G Syt9 synaptotagmin 9 ISO (MGI:3714434|PMID:17521570) SynGO PMID:17521570 MGI:3714434 NCBI chrNW_004936841:542,211...706,272 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12054
    cellular process 11242
      vesicle-mediated transport 1127
        vesicle-mediated transport in synapse 242
          synaptic vesicle exocytosis 129
            calcium-dependent activation of synaptic vesicle fusion 5
              regulation of calcium-dependent activation of synaptic vesicle fusion 0
Path 2
Term Annotations click to browse term
  biological_process 12054
    cellular process 11242
      cell communication 4266
        cell-cell signaling 1349
          synaptic signaling 658
            trans-synaptic signaling 637
              anterograde trans-synaptic signaling 629
                chemical synaptic transmission 629
                  neurotransmitter secretion 170
                    synaptic vesicle exocytosis 129
                      synaptic vesicle fusion to presynaptic active zone membrane 13
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane 10
                          positive regulation of synaptic vesicle fusion to presynaptic active zone membrane 5
                            calcium-dependent activation of synaptic vesicle fusion 5
                              regulation of calcium-dependent activation of synaptic vesicle fusion 0
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