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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-dependent activation of synaptic vesicle fusion
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Accession:GO:0099502 term browser browse the term
Definition:The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.


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calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 NCBI chr 6:17,872,670...17,877,502
Ensembl chr 6:17,873,521...17,903,184
JBrowse link
G SYT1 synaptotagmin 1 involved_in IEA
ISO
(MGI:69538|PMID:7954835) Ensembl
SynGO
PMID:7954835 GO_REF:0000107 MGI:69538 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732
JBrowse link
G SYT2 synaptotagmin 2 ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chr 7:497,387...509,338
Ensembl chr 7:497,394...502,952
JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367
JBrowse link
G SYT9 synaptotagmin 9 ISO (MGI:3714434|PMID:17521570) SynGO PMID:17521570 MGI:3714434 NCBI chr21:30,985,059...31,123,986
Ensembl chr21:30,986,521...31,162,414
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16149
    cellular process 15475
      vesicle-mediated transport 1470
        vesicle-mediated transport in synapse 265
          synaptic vesicle exocytosis 145
            calcium-dependent activation of synaptic vesicle fusion 5
              regulation of calcium-dependent activation of synaptic vesicle fusion 0
Path 2
Term Annotations click to browse term
  biological_process 16149
    cellular process 15475
      cell communication 6100
        cell-cell signaling 1632
          synaptic signaling 864
            trans-synaptic signaling 838
              anterograde trans-synaptic signaling 829
                chemical synaptic transmission 829
                  neurotransmitter secretion 191
                    synaptic vesicle exocytosis 145
                      synaptic vesicle fusion to presynaptic active zone membrane 22
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane 10
                          positive regulation of synaptic vesicle fusion to presynaptic active zone membrane 5
                            calcium-dependent activation of synaptic vesicle fusion 5
                              regulation of calcium-dependent activation of synaptic vesicle fusion 0
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