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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-dependent activation of synaptic vesicle fusion
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Accession:GO:0099502 term browser browse the term
Definition:The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.


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calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRRT2 proline rich transmembrane protein 2 ISO (MGI:5792766|PMID:27052163) SynGO PMID:27052163 MGI:5792766 Ensembl chr16:30,183,352...30,187,862 JBrowse link
G SYT1 synaptotagmin 1 ISO (MGI:69538|PMID:7954835) SynGO PMID:7954835 MGI:69538 NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923
JBrowse link
G SYT2 synaptotagmin 2 ISO (MGI:3695515|PMID:17192432) SynGO PMID:17192432 MGI:3695515 NCBI chr 1:178,187,872...178,308,522
Ensembl chr 1:182,490,401...182,538,123
JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:5554634|PMID:24267651) SynGO PMID:24267651 MGI:5554634 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375
JBrowse link
G SYT9 synaptotagmin 9 ISO (MGI:3714434|PMID:17521570) SynGO PMID:17521570 MGI:3714434 NCBI chr11:7,350,612...7,565,272
Ensembl chr11:7,032,803...7,247,187
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12618
    cellular process 11733
      vesicle-mediated transport 1156
        vesicle-mediated transport in synapse 244
          synaptic vesicle exocytosis 130
            calcium-dependent activation of synaptic vesicle fusion 5
              regulation of calcium-dependent activation of synaptic vesicle fusion 0
Path 2
Term Annotations click to browse term
  biological_process 12618
    cellular process 11733
      cell communication 4394
        cell-cell signaling 1373
          synaptic signaling 666
            trans-synaptic signaling 645
              anterograde trans-synaptic signaling 637
                chemical synaptic transmission 637
                  neurotransmitter secretion 171
                    synaptic vesicle exocytosis 130
                      synaptic vesicle fusion to presynaptic active zone membrane 13
                        regulation of synaptic vesicle fusion to presynaptic active zone membrane 10
                          positive regulation of synaptic vesicle fusion to presynaptic active zone membrane 5
                            calcium-dependent activation of synaptic vesicle fusion 5
                              regulation of calcium-dependent activation of synaptic vesicle fusion 0
paths to the root