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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial [2Fe-2S] assembly complex
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Accession:GO:0099128 term browser browse the term
Definition:A protein complex capable of forming 2Fe-2S clusters in mitochondria. In humans it consists of ISCU, NFS1, LYRM4, NDUFAB1 and FXN.
Synonyms:exact_synonym: mitochondrial ISCU complex
 related_synonym: mitochondrial iron-sulfur cluster assembly complex


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mitochondrial [2Fe-2S] assembly complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin part_of IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:6228237|PMID:21298097), (MGI:7327226|PMID:25597503)
(PMID:21298097), (PMID:29491838), (PMID:31101807)		 Ensembl
UniProt
RGD		 PMID:21298097 PMID:25597503 PMID:29491838 PMID:31101807 GO_REF:0000024 GO_REF:0000107 MGI:6228237 MGI:7327226 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Iscu iron-sulfur cluster assembly enzyme part_of ISO (MGI:6228237|PMID:21298097), (MGI:7327226|PMID:25597503)
(PMID:21298097), (PMID:31101807)		 RGD PMID:21298097 PMID:25597503 PMID:31101807 MGI:6228237 MGI:7327226 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
G Lyrm4 LYR motif containing 4 part_of ISO (MGI:6228237|PMID:21298097), (MGI:7327226|PMID:25597503)
(PMID:21298097), (PMID:31101807)		 RGD PMID:21298097 PMID:25597503 PMID:31101807 MGI:6228237 MGI:7327226 NCBI chr17:28,746,457...28,861,849
Ensembl chr17:28,746,469...28,861,750 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 part_of ISO
IEA		 (PMID:31101807)
GO_REF:0000107		 RGD
Ensembl		 PMID:31101807 GO_REF:0000107 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099 		JBrowse link
G Nfs1 NFS1 cysteine desulfurase part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6228237|PMID:21298097), (MGI:7327226|PMID:25597503)
(PMID:21298097), (PMID:31101807)		 UniProt
Ensembl
RGD		 PMID:21298097 PMID:25597503 PMID:31101807 GO_REF:0000024 GO_REF:0000107 MGI:6228237 MGI:7327226 NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20813
    protein-containing complex 6433
      iron-sulfur cluster assembly complex 17
        mitochondrial [2Fe-2S] assembly complex 5
Path 2
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      intracellular anatomical structure 15184
        cytoplasm 11877
          cytosol 4228
            sulfurtransferase complex 7
              L-cysteine desulfurase complex 5
                mitochondrial [2Fe-2S] assembly complex 5
paths to the root