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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial [2Fe-2S] assembly complex
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Accession:GO:0099128 term browser browse the term
Definition:A protein complex capable of forming 2Fe-2S clusters in mitochondria. In humans it consists of ISCU, NFS1, LYRM4, NDUFAB1 and FXN.
Synonyms:exact_synonym: mitochondrial ISCU complex
 related_synonym: mitochondrial iron-sulfur cluster assembly complex



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mitochondrial [2Fe-2S] assembly complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031
JBrowse link
G ISCU iron-sulfur cluster assembly enzyme part_of IEA Ensembl GO_REF:0000107 NCBI chr12:106,132,987...106,140,879
Ensembl chr12:109,529,162...109,537,053
JBrowse link
G LOC100989931 acyl carrier protein, mitochondrial part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:170,136,429...170,137,102
Ensembl chr16:23,833,485...23,849,085
JBrowse link
G LYRM4 LYR motif containing 4 part_of ISO (PMID:21298097), (PMID:31101807)
(PMID:21298097), (PMID:25597503)
UniProt PMID:21298097 PMID:25597503 PMID:31101807 NCBI chr 6:4,887,010...5,096,384
Ensembl chr 6:5,127,918...5,279,038
JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 part_of ISO (PMID:31101807) FlyBase PMID:31101807 NCBI chr16:14,513,734...14,529,087
Ensembl chr16:23,833,485...23,849,085
JBrowse link
G NFS1 NFS1 cysteine desulfurase part_of IEA Ensembl GO_REF:0000107 NCBI chr20:31,994,509...32,026,776 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17444
    protein-containing complex 5712
      iron-sulfur cluster assembly complex 18
        mitochondrial [2Fe-2S] assembly complex 6
Path 2
Term Annotations click to browse term
  cellular_component 17444
    cellular anatomical structure 17222
      intracellular anatomical structure 13864
        cytoplasm 10864
          cytosol 3852
            sulfurtransferase complex 7
              L-cysteine desulfurase complex 6
                mitochondrial [2Fe-2S] assembly complex 6
paths to the root