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Term:activating signal cointegrator 1 complex
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Accession:GO:0099053 term browser browse the term
Definition:A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3.
Synonyms:exact_synonym: ASC-1 complex

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activating signal cointegrator 1 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascc2 activating signal cointegrator 1 complex subunit 2 ISO (PMID:12077347) RGD PMID:12077347 NCBI chr14:84,873,507...84,913,923
Ensembl chr14:84,876,781...84,913,617
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G Ascc3 activating signal cointegrator 1 complex subunit 3 IEA
PMID:12077347 GO_REF:0000107 NCBI chr20:55,253,670...55,557,249
Ensembl chr20:55,253,686...55,556,473
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G Trip4 thyroid hormone receptor interactor 4 ISO (PMID:12077347) RGD PMID:12077347 NCBI chr 8:71,369,121...71,533,281
Ensembl chr 8:71,371,370...71,533,459
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  cellular_component 20609
    protein-containing complex 6093
      transcription regulator complex 434
        RNA polymerase II transcription regulator complex 162
          activating signal cointegrator 1 complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.