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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane repolarization during ventricular cardiac muscle cell action potential
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Accession:GO:0098915 term browser browse the term
Definition:The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
Synonyms:related_synonym: electrocardiogram T wave;   regulation of ventricular cardiac muscle repolarization;   ventricular repolarization



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membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLG1 discs large MAGUK scaffold protein 1 involved_in ISS
IEA
(PMID:25447080) BHF-UCL
Ensembl
PMID:25447080 GO_REF:0000107 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP (PMID:9354802) BHF-UCL PMID:9354802 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,180,729...34,371,381
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,052,190...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IMP (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA GOC GO_REF:0000108 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in IMP (PMID:20558321) BHF-UCL PMID:20558321 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
IEA
(PMID:8528244)
(PMID:12766260), (PMID:15004216)
BHF-UCL
MGI
GO_Central
Ensembl
PMID:8528244 PMID:12766260 PMID:15004216 GO_REF:0000033 GO_REF:0000107 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA GOC GO_REF:0000108 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IMP (PMID:22987075) BHF-UCL PMID:22987075 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729
JBrowse link
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS1 nitric oxide synthase 1 involved_in TAS (PMID:18337493) BHF-UCL PMID:18337493 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS1AP nitric oxide synthase 1 adaptor protein acts_upstream_of ISS (PMID:18337493) BHF-UCL PMID:18337493 NCBI chr 1:162,069,691...162,370,475
Ensembl chr 1:162,069,691...162,370,475
JBrowse link
G RNF207 ring finger protein 207 involved_in
acts_upstream_of
ISS
IMP
(PMID:25281747) BHF-UCL PMID:25281747 GO_REF:0000024 NCBI chr 1:6,206,119...6,221,299
Ensembl chr 1:6,205,475...6,221,299
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR1-1 microRNA 1-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr20:62,554,306...62,554,376
Ensembl chr20:62,554,306...62,554,376
JBrowse link
G MIR1-2 microRNA 1-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr18:21,829,004...21,829,088
Ensembl chr18:21,829,004...21,829,088
JBrowse link
regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR133A1 microRNA 133a-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr18:21,825,698...21,825,785
Ensembl chr18:21,825,698...21,825,785
JBrowse link
G MIR133A2 microRNA 133a-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr20:62,564,912...62,565,013
Ensembl chr20:62,564,912...62,565,013
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19699
    biological regulation 13542
      regulation of biological quality 3621
        regulation of membrane potential 562
          action potential 207
            cardiac muscle cell action potential 89
              membrane repolarization during cardiac muscle cell action potential 30
                membrane repolarization during ventricular cardiac muscle cell action potential 20
                  negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential 1
                  positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 5
                  regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 8
Path 2
Term Annotations click to browse term
  biological_process 19699
    multicellular organismal process 8521
      system process 2771
        circulatory system process 732
          blood circulation 648
            heart contraction 301
              cardiac muscle contraction 169
                cardiac muscle cell contraction 95
                  cardiac muscle cell action potential involved in contraction 64
                    ventricular cardiac muscle cell action potential 39
                      membrane repolarization during ventricular cardiac muscle cell action potential 20
                        negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential 1
                        positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 5
                        regulation of membrane repolarization during ventricular cardiac muscle cell action potential + 8
paths to the root