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ONTOLOGY REPORT - ANNOTATIONS


Term:postsynaptic neurotransmitter receptor internalization
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Accession:GO:0098884 term browser browse the term
Definition:A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle.
Synonyms:exact_synonym: postsynaptic neurotransmitter receptor endocytosis



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postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2b1 adaptor related protein complex 2 subunit beta 1 involved_in IMP
ISO
EXP
IDA
NAS
PMID:17289840
(PMID:24217640)
RGD PMID:24217640 PMID:17289840 PMID:17289840 PMID:17289840 PMID:17289840 RGD:13432317, RGD:13432317, RGD:13432317, RGD:13432317 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 involved_in IMP
ISO
IDA
EXP
PMID:17289840
(PMID:24217640)
RGD PMID:24217640 PMID:17289840 PMID:17289840 PMID:17289840 RGD:13432317, RGD:13432317, RGD:13432317 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 involved_in IMP
NAS
IDA
EXP
PMID:17289840 SynGO PMID:17289840 PMID:17289840 PMID:17289840 PMID:17289840 RGD:13432317, RGD:13432317, RGD:13432317, RGD:13432317 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 involved_in ISO (PMID:27568566) RGD PMID:27568566 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Caly calcyon neuron-specific vesicular protein involved_in ISO (PMID:19120439) RGD PMID:19120439 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
JBrowse link
G Dnm3 dynamin 3 involved_in IMP PMID:17880892 SynGO PMID:17880892 RGD:8553820 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 involved_in IDA
IEP
IMP
PMID:25023288 SynGO PMID:25023288 PMID:25023288 PMID:25023288 RGD:13702241, RGD:13702241, RGD:13702241 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Myo6 myosin VI involved_in ISO (PMID:15657400) RGD PMID:15657400 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:25972173) RGD PMID:25972173 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in IMP
IDA
PMID:15629704 SynGO PMID:15629704 PMID:15629704 RGD:155230721, RGD:155230721 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rab5al1 Rab5a, member RAS oncogene family-like 1 involved_in IMP
IDA
PMID:15629704 SynGO PMID:15629704 PMID:15629704 RGD:155230721, RGD:155230721 NCBI chr14:68,332,360...68,334,470
Ensembl chr14:68,332,558...68,333,205
JBrowse link
G Sh3glb2 SH3 domain-containing GRB2-like endophilin B2 involved_in IDA
IEP
IMP
PMID:26776730 SynGO PMID:26776730 PMID:26776730 PMID:26776730 RGD:11564596, RGD:11564596, RGD:11564596 NCBI chr 3:13,616,936...13,631,785
Ensembl chr 3:13,616,938...13,631,757
JBrowse link
G Synj1 synaptojanin 1 involved_in ISO (MGI:5819348|PMID:18987319) RGD PMID:18987319 MGI:5819348 NCBI chr11:30,192,629...30,269,447
Ensembl chr11:30,192,629...30,269,220
JBrowse link
G Tmub1 transmembrane and ubiquitin-like domain containing 1 involved_in IDA PMID:18665261 SynGO PMID:18665261 RGD:405650208 NCBI chr 4:10,729,494...10,732,060
Ensembl chr 4:10,729,250...10,732,060
JBrowse link
regulation of postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in IMP
IDA
PMID:19169250 SynGO PMID:19169250 PMID:19169250 RGD:2313185, RGD:2313185 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein involved_in ISO (PMID:17088211) RGD PMID:17088211 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 involved_in ISO (PMID:21496646) RGD PMID:21496646 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548
JBrowse link
G Cblb Cbl proto-oncogene B involved_in ISO (PMID:32606037) RGD PMID:32606037 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Drd3 dopamine receptor D3 involved_in EXP
IDA
IEP
PMID:16510729 SynGO PMID:16510729 PMID:16510729 PMID:16510729 RGD:13702467, RGD:13702467, RGD:13702467 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 involved_in IEA
ISO
GO_REF:0000107
(PMID:18832154)
Ensembl
RGD
PMID:18832154 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Efnb2 ephrin B2 involved_in ISO (PMID:19160501) RGD PMID:19160501 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
JBrowse link
G Gsg1l GSG1-like involved_in ISO (PMID:26932439) RGD PMID:26932439 NCBI chr 1:180,440,398...180,654,342
Ensembl chr 1:180,442,630...180,654,134
JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IDA
IMP
IEP
PMID:15310851 SynGO PMID:15310851 PMID:15310851 PMID:15310851 RGD:13702182, RGD:13702182, RGD:13702182 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:12839988) RGD PMID:12839988 NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Hpca hippocalcin involved_in IMP
IDA
PMID:20852624 SynGO PMID:20852624 PMID:20852624 RGD:13702412, RGD:13702412 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 involved_in IMP
ISO
(PMID:20547133) RGD PMID:20547133 PMID:26884337 RGD:11560558 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO
IEA
(PMID:18549786)
GO_REF:0000107
RGD
Ensembl
PMID:18549786 GO_REF:0000107 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 involved_in IMP
IDA
EXP
IEP
PMID:25996636 SynGO PMID:25996636 PMID:25996636 PMID:25996636 PMID:25996636 RGD:155230734, RGD:155230734, RGD:155230734, RGD:155230734 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:23760271) RGD PMID:23760271 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in EXP
IDA
IMP
PMID:14642282 SynGO PMID:14642282 PMID:14642282 PMID:14642282 RGD:2317402, RGD:2317402, RGD:2317402 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mib2 MIB E3 ubiquitin protein ligase 2 involved_in IDA PMID:17962190 SynGO PMID:17962190 RGD:405650227 NCBI chr 5:166,243,776...166,259,944
Ensembl chr 5:166,243,776...166,259,650
JBrowse link
G Ncdn neurochondrin involved_in ISO (PMID:34907024) RGD PMID:34907024 NCBI chr 5:139,037,807...139,047,645
Ensembl chr 5:139,037,819...139,047,568
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in IDA
IMP
IEP
PMID:21148011 SynGO PMID:21148011 PMID:21148011 PMID:21148011 RGD:13702142, RGD:13702142, RGD:13702142 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in ISO (PMID:28212375) RGD PMID:28212375 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:16221846) RGD PMID:16221846 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Numb NUMB, endocytic adaptor protein involved_in IEA
ISO
GO_REF:0000107
(PMID:26621723)
Ensembl
RGD
PMID:26621723 GO_REF:0000107 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354
JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO (PMID:24966368) RGD PMID:24966368 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 involved_in IDA
IMP
PMID:16617342
PMID:23918399
SynGO PMID:16617342 PMID:23918399 PMID:16617342 PMID:23918399 RGD:13702454, RGD:13702399, RGD:13702454, RGD:13702399 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313
JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IMP
IDA
IEP
PMID:28855251 SynGO PMID:28855251 PMID:28855251 PMID:28855251 RGD:13702248, RGD:13702248, RGD:13702248 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma involved_in ISO (PMID:22243752) RGD PMID:22243752 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha involved_in ISO (PMID:11733061) RGD PMID:11733061 NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Rabep1 rabaptin, RAB GTPase binding effector protein 1 involved_in ISO (PMID:34564930) RGD PMID:34564930 NCBI chr10:55,566,156...55,667,595
Ensembl chr10:55,566,185...55,665,973
JBrowse link
G Rala RAS like proto-oncogene A involved_in EXP
IDA
IMP
PMID:19823667 SynGO PMID:19823667 PMID:19823667 PMID:19823667 RGD:2324918, RGD:2324918, RGD:2324918 NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Rnf216 ring finger protein 216 involved_in IMP
IDA
PMID:24945773 SynGO PMID:24945773 PMID:24945773 RGD:11553202, RGD:11553202 NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304
JBrowse link
G Rnf220 ring finger protein 220 involved_in ISO (PMID:36179027) RGD PMID:36179027 NCBI chr 5:130,739,173...130,961,386
Ensembl chr 5:130,739,183...130,961,418
JBrowse link
G Rnf34 ring finger protein 34 involved_in IMP
IDA
PMID:25193658 SynGO PMID:25193658 PMID:25193658 RGD:10047328, RGD:10047328 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586
JBrowse link
G Scrib scribble planar cell polarity protein involved_in IDA
IMP
PMID:25310985 SynGO PMID:25310985 PMID:25310985 RGD:12050130, RGD:12050130 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331
JBrowse link
G Sirt2 sirtuin 2 involved_in IDA
EXP
IMP
IEP
PMID:28793258 SynGO PMID:28793258 PMID:28793258 PMID:28793258 PMID:28793258 RGD:13702139, RGD:13702139, RGD:13702139, RGD:13702139 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:33661101) RGD PMID:33661101 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 involved_in IMP
IEP
IDA
PMID:15541315 RGD
SynGO
PMID:24191017 PMID:15541315 PMID:15541315 PMID:15541315 RGD:13209020, RGD:2314546, RGD:2314546, RGD:2314546 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322
JBrowse link
G Synj1 synaptojanin 1 involved_in ISO (PMID:18987319) RGD PMID:18987319 NCBI chr11:30,192,629...30,269,447
Ensembl chr11:30,192,629...30,269,220
JBrowse link
G Syt17 synaptotagmin 17 involved_in ISO (PMID:31387992) RGD PMID:31387992 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960
JBrowse link
G Tamalin trafficking regulator and scaffold protein tamalin involved_in ISO (PMID:32376687) RGD PMID:32376687 NCBI chr 7:132,338,900...132,359,519
Ensembl chr 7:132,338,900...132,346,666
JBrowse link
G Tspan7 tetraspanin 7 involved_in IDA
IMP
PMID:22445342 SynGO PMID:22445342 PMID:22445342 RGD:11068824, RGD:11068824 NCBI chr  X:12,208,783...12,306,092
Ensembl chr  X:12,208,783...12,306,131
JBrowse link
G Usp46 ubiquitin specific peptidase 46 involved_in IMP
IDA
IEP
PMID:26077708 SynGO PMID:26077708 PMID:26077708 PMID:26077708 RGD:11056935, RGD:11056935, RGD:11056935 NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
JBrowse link
G Vac14 VAC14 component of PIKFYVE complex involved_in ISO (PMID:22842785) RGD PMID:22842785 NCBI chr19:38,590,569...38,691,911
Ensembl chr19:38,590,569...38,691,909
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    biological regulation 13396
      regulation of biological quality 3375
        regulation of postsynaptic membrane neurotransmitter receptor levels 184
          postsynaptic neurotransmitter receptor internalization 55
            regulation of postsynaptic neurotransmitter receptor internalization 42
Path 2
Term Annotations click to browse term
  biological_process 19872
    localization 5633
      establishment of localization 4939
        transport 4625
          vesicle-mediated transport 1633
            endocytosis 731
              receptor-mediated endocytosis 298
                receptor internalization 174
                  neurotransmitter receptor internalization 62
                    postsynaptic neurotransmitter receptor internalization 55
                      regulation of postsynaptic neurotransmitter receptor internalization 42
paths to the root