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ONTOLOGY REPORT - ANNOTATIONS


Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal


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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO UniProtKB:P14106|UniProtKB:Q02105 (MGI:6275119|PMID:27033548) RGD PMID:27033548 MGI:6275119 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C1qb complement C1q B chain involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P98086|UniProtKB:Q02105 (MGI:6275119|PMID:27033548)
Ensembl
RGD
PMID:27033548 GO_REF:0000107 MGI:6275119 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C1qc complement C1q C chain involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P14106|UniProtKB:P98086 (MGI:6275119|PMID:27033548)
Ensembl
RGD
PMID:27033548 GO_REF:0000107 MGI:6275119 NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in EXP
IMP
IDA
PMID:17143272 SynGO PMID:17143272, PMID:17143272, PMID:17143272 RGD:8554385, RGD:8554385, RGD:8554385 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5287328|PMID:21778362)
UniProt
RGD
PMID:21778362 GO_REF:0000024 MGI:5287328 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Epha4 Eph receptor A4 involved_in IDA
ISO
EXP
IMP
PMID:17143272
(MGI:2449844|PMID:12496762)
RGD PMID:12496762, PMID:17143272, PMID:17143272, PMID:17143272 MGI:2449844, RGD:8554385, RGD:8554385, RGD:8554385 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISO (MGI:3696283|PMID:17143272) RGD PMID:17143272 MGI:3696283 NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852
JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO (MGI:3801262|PMID:18083105) RGD PMID:18083105 MGI:3801262 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C3 complement C3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3801262|PMID:18083105)
Ensembl
RGD
PMID:18083105 GO_REF:0000107 MGI:3801262 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (MGI:6189359|PMID:22632727) RGD PMID:22632727 MGI:6189359 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) RGD PMID:30548312 MGI:6275756 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6284411|PMID:29752066) RGD PMID:29752066 MGI:6284411 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708) RGD PMID:33097708 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          cell junction organization 798
            synapse organization 510
              synapse pruning 10
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 1
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 1
paths to the root