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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal


show annotations for term's descendants           Sort by:
synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO UniProtKB:P14106|UniProtKB:Q02105 (PMID:27033548) RGD PMID:27033548 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C1qb complement C1q B chain involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P98086|UniProtKB:Q02105 (PMID:27033548)		 Ensembl
RGD		 PMID:27033548 GO_REF:0000107 NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1qc complement C1q C chain involved_in ISO
IEA		 UniProtKB:P14106|UniProtKB:P98086 (PMID:27033548)
GO_REF:0000107		 RGD
Ensembl		 PMID:27033548 GO_REF:0000107 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21778362)		 UniProt
RGD		 PMID:21778362 GO_REF:0000024 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO
IEA		 (PMID:12496762)
GO_REF:0000107		 RGD
Ensembl		 PMID:12496762 GO_REF:0000107 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO (PMID:18083105) RGD PMID:18083105 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C3 complement C3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18083105)		 Ensembl
RGD		 PMID:18083105 GO_REF:0000107 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) RGD PMID:22632727 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) RGD PMID:30548312 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29752066) RGD PMID:29752066 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IEA		 (PMID:33097708)
GO_REF:0000107		 RGD
Ensembl		 PMID:33097708 GO_REF:0000107 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:34642249)		 UniProt
Ensembl
RGD		 PMID:34642249 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:124,970,363...125,074,919
Ensembl chr 6:119,242,188...119,345,240 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb3 adhesion G protein-coupled receptor B3 involved_in ISO
IEA		 (PMID:25611509)
GO_REF:0000107		 RGD
Ensembl		 PMID:25611509 GO_REF:0000107 NCBI chr 9:34,917,474...35,645,350
Ensembl chr 9:27,421,168...28,148,855 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G C1ql1 complement C1q like 1 involved_in ISO
IEA		 (PMID:25611509)
GO_REF:0000107		 RGD
Ensembl		 PMID:25611509 GO_REF:0000107 NCBI chr10:88,402,219...88,409,649
Ensembl chr10:87,902,137...87,909,310 		JBrowse link
G Cd47 Cd47 molecule involved_in ISO (PMID:30308165) RGD PMID:30308165 NCBI chr11:64,374,816...64,438,763
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in IDA
IMP
EXP		 PMID:17143272 SynGO PMID:17143272 PMID:17143272 PMID:17143272 RGD:8554385, RGD:8554385, RGD:8554385 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Epha4 Eph receptor A4 involved_in IMP
IEP
EXP
IDA		 PMID:17143272 SynGO PMID:17143272 PMID:17143272 PMID:17143272 PMID:17143272 RGD:8554385, RGD:8554385, RGD:8554385, RGD:8554385 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:24831527) RGD PMID:24831527 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISO
IEA		 (PMID:17143272)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143272 GO_REF:0000107 NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:88,146,956...88,244,914 		JBrowse link
G Plxnc1 plexin C1 involved_in ISO
IEA		 (PMID:24831527)
GO_REF:0000107		 RGD
Ensembl		 PMID:24831527 GO_REF:0000107 NCBI chr 7:31,276,978...31,430,823
Ensembl chr 7:29,390,048...29,543,779 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 involved_in ISO
IEA		 (PMID:22678360)
GO_REF:0000107		 RGD
Ensembl		 PMID:22678360 GO_REF:0000107 NCBI chr10:63,867,503...63,890,872
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in ISO
IEA		 (PMID:34407949)
GO_REF:0000107		 RGD
Ensembl		 PMID:34407949 GO_REF:0000107 NCBI chr13:86,995,124...87,021,770
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          cell junction organization 988
            synapse organization 709
              synapse pruning 19
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 13
paths to the root