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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular oxidant detoxification
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Accession:GO:0098869 term browser browse the term
Definition:Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.


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cellular oxidant detoxification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx1 glutathione peroxidase 1 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G Gpx2 glutathione peroxidase 2 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr12:76,792,335...76,795,554
Ensembl chr12:76,792,333...76,795,554
JBrowse link
G Gpx3 glutathione peroxidase 3 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr11:54,902,854...54,910,387
Ensembl chr11:54,902,453...54,910,377
JBrowse link
G Gpx5 glutathione peroxidase 5 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr13:21,286,429...21,292,727
Ensembl chr13:21,286,429...21,292,731
JBrowse link
G Gpx6 glutathione peroxidase 6 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr13:21,295,465...21,319,625
Ensembl chr13:21,312,125...21,319,624
JBrowse link
G Gpx7 glutathione peroxidase 7 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr 4:108,400,217...108,406,713
Ensembl chr 4:108,400,390...108,406,961
JBrowse link
G Gpx8 glutathione peroxidase 8 (putative) IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr13:113,042,757...113,046,430
Ensembl chr13:113,042,753...113,046,410
JBrowse link
G Gsr glutathione reductase IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gsto2 glutathione S-transferase omega 2 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr19:47,865,438...47,886,308
Ensembl chr19:47,865,534...47,886,324
JBrowse link
G Iyd iodotyrosine deiodinase IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr10:3,540,274...3,554,880
Ensembl chr10:3,540,240...3,554,877
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chr13:119,335,527...119,409,257
Ensembl chr13:119,335,448...119,408,997
Ensembl chr13:119,335,448...119,408,997
JBrowse link
G Prdx4 peroxiredoxin 4 IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr  X:155,323,918...155,342,272
Ensembl chr  X:155,323,918...155,340,754
JBrowse link
G Prdx6 peroxiredoxin 6 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 1:161,240,112...161,251,210
Ensembl chr 1:161,240,112...161,251,219
JBrowse link
G Selenot selenoprotein T ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 3:58,576,636...58,593,544
Ensembl chr 3:58,576,636...58,593,133
JBrowse link
G Sesn1 sestrin 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:41,810,574...41,908,436
Ensembl chr10:41,809,935...41,908,424
JBrowse link
G Sesn2 sestrin 2 NOT ISO (PMID:26612684)
(PMID:19113821)
(PMID:15105503)
UniProtKB PMID:15105503, PMID:19113821, PMID:26612684 NCBI chr 4:132,492,804...132,510,456
Ensembl chr 4:132,492,032...132,510,501
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) IBA (MGI:MGI:6201960|PMID:21873635) GOC PMID:21873635 MGI:MGI:6201960 NCBI chr 2:152,105,524...152,111,376
Ensembl chr 2:152,105,516...152,111,376
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule IMP (MGI:MGI:4850200|PMID:20978343) BHF-UCL PMID:20978343 MGI:MGI:4850200 NCBI chr 5:17,781,690...17,888,959
Ensembl chr 5:17,781,690...17,888,801
JBrowse link
G Dhfr dihydrofolate reductase IMP (MGI:MGI:5645206|PMID:19666465) BHF-UCL PMID:19666465 MGI:MGI:5645206 NCBI chr13:92,354,783...92,389,053
Ensembl chr13:92,354,726...92,389,053
JBrowse link
G Fbln5 fibulin 5 IMP (MGI:MGI:3610795|PMID:15528465) BHF-UCL PMID:15528465 MGI:MGI:3610795 NCBI chr12:101,746,565...101,819,119
Ensembl chr12:101,746,565...101,819,055
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr14:47,153,895...47,189,413
Ensembl chr14:47,153,895...47,189,413
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IMP (MGI:MGI:4850200|PMID:20978343) BHF-UCL PMID:20978343 MGI:MGI:4850200 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A-IV ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 9:46,240,844...46,243,458
Ensembl chr 9:46,240,696...46,243,459
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IMP (MGI:MGI:3616392|PMID:16371425) MGI PMID:16371425 MGI:MGI:3616392 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Ccs copper chaperone for superoxide dismutase IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr19:4,825,366...4,839,356
Ensembl chr19:4,825,366...4,839,332
JBrowse link
G Fancc Fanconi anemia, complementation group C IGI (MGI:MGI:2149223|PMID:11493445) MGI PMID:11493445 MGI:MGI:2149223 NCBI chr13:63,301,334...63,497,292
Ensembl chr13:63,285,043...63,497,278
JBrowse link
G Mpo myeloperoxidase IMP (MGI:MGI:1333719|PMID:10085024) MGI PMID:10085024 MGI:MGI:1333719 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Mt3 metallothionein 3 ISO (PMID:12383939) UniProtKB PMID:12383939 NCBI chr 8:94,152,607...94,154,148
Ensembl chr 8:94,152,607...94,154,146
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Prdx1 peroxiredoxin 1 IMP
IBA
(MGI:MGI:3611115|PMID:16170382)
(MGI:MGI:6201960|PMID:21873635)
(MGI:MGI:3695235|PMID:16880205)
MGI
GO_Central
PMID:16170382, PMID:16880205, PMID:21873635 MGI:MGI:3611115, MGI:MGI:3695235, MGI:MGI:6201960 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822
JBrowse link
G Prdx2 peroxiredoxin 2 IMP
IBA
ISO
(MGI:MGI:4850200|PMID:20978343)
(MGI:MGI:6201960|PMID:21873635)
BHF-UCL
GO_Central
MGI
PMID:20978343, PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:4850200, MGI:MGI:6201960 NCBI chr 8:84,969,622...84,974,811
Ensembl chr 8:84,969,587...84,974,834
JBrowse link
G Sod1 superoxide dismutase 1, soluble IGI
IBA
IMP
ISO
TAS
(MGI:MGI:2149223|PMID:11493445)
(MGI:MGI:6201960|PMID:21873635)
(MGI:MGI:1201750|PMID:9516486), (MGI:MGI:1314762|PMID:9788901)
(MGI:MGI:3625573|PMID:12433839), (MGI:MGI:3710732|PMID:17448893)
(MGI:MGI:1342989|PMID:10436316), (MGI:MGI:1351737|PMID:10471451), (MGI:MGI:2149223|PMID:11493445), (MGI:MGI:80951|PMID:8673102)
(MGI:MGI:2152694|PMID:11557311)
(MGI:MGI:1353351|PMID:10679476)
MGI
GO_Central
RGD
PMID:8673102, PMID:9516486, PMID:9788901, PMID:10436316, PMID:10471451, PMID:10679476, PMID:11493445, PMID:11557311, PMID:12433839, PMID:17448893, PMID:21873635 GO_REF:0000096, MGI:MGI:1201750, MGI:MGI:1314762, MGI:MGI:1342989, MGI:MGI:1351737, MGI:MGI:1353351, MGI:MGI:2149223, MGI:MGI:2152694, MGI:MGI:3625573, MGI:MGI:3710732, MGI:MGI:4417868, MGI:MGI:6201960, MGI:MGI:80951 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial IMP
ISO
(MGI:MGI:3765405|PMID:16873728) MGI
RGD
PMID:16873728 GO_REF:0000096, MGI:MGI:3765405, MGI:MGI:4417868, MGI:MGI:4834177 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sod3 superoxide dismutase 3, extracellular IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23386
    detoxification 65
      cellular detoxification 52
        cellular oxidant detoxification 34
          cellular detoxification of hydrogen peroxide 0
          removal of superoxide radicals + 17
Path 2
Term Annotations click to browse term
  biological_process 23386
    cellular process 17413
      cellular response to stimulus 8394
        cellular response to chemical stimulus 3600
          cellular response to toxic substance 65
            cellular detoxification 52
              cellular oxidant detoxification 34
                cellular detoxification of hydrogen peroxide 0
                removal of superoxide radicals + 17
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.