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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular oxidant detoxification
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Accession:GO:0098869 term browser browse the term
Definition:Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.


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cellular oxidant detoxification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin IEA GOC GO_REF:0000108 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein IEA GOC GO_REF:0000108 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
JBrowse link
G APOE apolipoprotein E IEA GOC GO_REF:0000108 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOM apolipoprotein M IEA GOC GO_REF:0000108 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
JBrowse link
G CAT catalase IEA GOC GO_REF:0000108 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CLIC2 chloride intracellular channel 2 IEA GOC GO_REF:0000108 NCBI chr  X:155,276,211...155,334,614
Ensembl chr  X:155,276,211...155,334,657
JBrowse link
G CYGB cytoglobin IEA GOC GO_REF:0000108 NCBI chr17:76,527,356...76,557,692
Ensembl chr17:76,527,356...76,551,175
JBrowse link
G DUOX1 dual oxidase 1 IEA GOC GO_REF:0000108 NCBI chr15:45,129,994...45,165,578
Ensembl chr15:45,129,933...45,165,576
JBrowse link
G DUOX2 dual oxidase 2 IEA GOC GO_REF:0000108 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,344
Ensembl chr15:45,092,650...45,114,344
JBrowse link
G EPX eosinophil peroxidase IEA GOC GO_REF:0000108 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174
JBrowse link
G FABP1 fatty acid binding protein 1 IEA GOC GO_REF:0000108 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G GPX1 glutathione peroxidase 1 IEA GOC GO_REF:0000108 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GPX2 glutathione peroxidase 2 IEA GOC GO_REF:0000108 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,905
JBrowse link
G GPX3 glutathione peroxidase 3 IEA GOC GO_REF:0000108 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,438...151,028,992
JBrowse link
G GPX4 glutathione peroxidase 4 IEA GOC GO_REF:0000108 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,926...1,106,791
JBrowse link
G GPX5 glutathione peroxidase 5 IEA GOC GO_REF:0000108 NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955
JBrowse link
G GPX6 glutathione peroxidase 6 IEA GOC GO_REF:0000108 NCBI chr 6:28,503,296...28,515,793
Ensembl chr 6:28,503,296...28,528,215
JBrowse link
G GPX7 glutathione peroxidase 7 IEA GOC GO_REF:0000108 NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051
JBrowse link
G GPX8 glutathione peroxidase 8 (putative) IEA GOC GO_REF:0000108 NCBI chr 5:55,160,155...55,167,297
Ensembl chr 5:55,160,167...55,167,297
JBrowse link
G GSR glutathione-disulfide reductase IEA GOC GO_REF:0000108 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 IEA GOC GO_REF:0000108 NCBI chr 6:52,791,371...52,803,827
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 IEA GOC GO_REF:0000108 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G GSTM2 glutathione S-transferase mu 2 IEA GOC GO_REF:0000108 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTO1 glutathione S-transferase omega 1 IEA GOC GO_REF:0000108 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link
G GSTO2 glutathione S-transferase omega 2 IEA GOC GO_REF:0000108 NCBI chr10:104,267,626...104,304,950
Ensembl chr10:104,268,873...104,304,950
JBrowse link
G GSTP1 glutathione S-transferase pi 1 IEA GOC GO_REF:0000108 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 IEA GOC GO_REF:0000108
G GSTZ1 glutathione S-transferase zeta 1 IEA GOC GO_REF:0000108 NCBI chr14:77,321,002...77,331,597
Ensembl chr14:77,320,996...77,331,597
JBrowse link
G HBA1 hemoglobin subunit alpha 1 IEA GOC GO_REF:0000108 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522
JBrowse link
G HBA2 hemoglobin subunit alpha 2 IEA GOC GO_REF:0000108 NCBI chr16:172,876...173,710
Ensembl chr16:172,876...173,710
JBrowse link
G HBB hemoglobin subunit beta IEA GOC GO_REF:0000108 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395
JBrowse link
G HBD hemoglobin subunit delta IEA GOC GO_REF:0000108 NCBI chr11:5,232,838...5,234,483
Ensembl chr11:5,232,678...5,243,657
JBrowse link
G HBE1 hemoglobin subunit epsilon 1 IEA GOC GO_REF:0000108 NCBI chr11:5,268,345...5,269,945
Ensembl chr11:5,268,345...5,505,652
JBrowse link
G HBG1 hemoglobin subunit gamma 1 IEA GOC GO_REF:0000108 NCBI chr11:5,248,269...5,249,857
Ensembl chr11:5,248,079...5,249,859
Ensembl chr11:5,248,079...5,249,859
JBrowse link
G HBG2 hemoglobin subunit gamma 2 IEA GOC GO_REF:0000108 NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605
JBrowse link
G HBM hemoglobin subunit mu IEA GOC GO_REF:0000108 NCBI chr16:165,978...166,764
Ensembl chr16:153,892...166,764
JBrowse link
G HBQ1 hemoglobin subunit theta 1 IEA GOC GO_REF:0000108 NCBI chr16:180,459...181,179
Ensembl chr16:180,459...181,179
JBrowse link
G HBZ hemoglobin subunit zeta IEA GOC GO_REF:0000108 NCBI chr16:152,644...154,503
Ensembl chr16:142,728...154,503
JBrowse link
G HP haptoglobin IEA GOC GO_REF:0000108 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G IPCEF1 interaction protein for cytohesin exchange factors 1 IEA GOC GO_REF:0000108 NCBI chr 6:154,154,496...154,356,803
Ensembl chr 6:154,154,496...154,356,792
JBrowse link
G IYD iodotyrosine deiodinase IEA GOC GO_REF:0000108 NCBI chr 6:150,368,854...150,405,969
Ensembl chr 6:150,368,892...150,405,969
JBrowse link
G KDM3B lysine demethylase 3B IEA GOC GO_REF:0000108 NCBI chr 5:138,352,685...138,437,027
Ensembl chr 5:138,352,685...138,437,028
JBrowse link
G LOXHD1 lipoxygenase homology domains 1 IEA GOC GO_REF:0000108 NCBI chr18:46,476,961...46,657,220
Ensembl chr18:46,476,972...46,657,220
JBrowse link
G LPO lactoperoxidase IEA GOC GO_REF:0000108 NCBI chr17:58,238,550...58,268,518
Ensembl chr17:58,218,548...58,268,518
JBrowse link
G LTC4S leukotriene C4 synthase IEA GOC GO_REF:0000108 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 IEA GOC GO_REF:0000108 NCBI chr12:16,347,115...16,377,192
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MGST2 microsomal glutathione S-transferase 2 IEA GOC GO_REF:0000108 NCBI chr 4:139,665,725...139,754,608
Ensembl chr 4:139,665,768...139,740,745
JBrowse link
G MGST3 microsomal glutathione S-transferase 3 IEA GOC GO_REF:0000108 NCBI chr 1:165,631,234...165,656,136
Ensembl chr 1:165,631,213...165,661,796
JBrowse link
G MPO myeloperoxidase IEA GOC GO_REF:0000108 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G NNT nicotinamide nucleotide transhydrogenase IEA Ensembl GO_REF:0000107 NCBI chr 5:43,601,092...43,707,396
Ensembl chr 5:43,602,692...43,707,405
JBrowse link
G NXN nucleoredoxin IEA GOC GO_REF:0000108 NCBI chr17:799,310...979,776
Ensembl chr17:799,310...979,776
JBrowse link
G PARK7 Parkinsonism associated deglycase IEA GOC GO_REF:0000108 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PRDX1 peroxiredoxin 1 IEA GOC GO_REF:0000108 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,511,036...45,523,047
JBrowse link
G PRDX2 peroxiredoxin 2 IEA GOC GO_REF:0000108 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G PRDX3 peroxiredoxin 3 IEA GOC GO_REF:0000108 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812
JBrowse link
G PRDX4 peroxiredoxin 4 IEA GOC GO_REF:0000108 NCBI chr  X:23,667,493...23,686,397
Ensembl chr  X:23,664,262...23,686,397
JBrowse link
G PRDX5 peroxiredoxin 5 IEA GOC GO_REF:0000108 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
JBrowse link
G PRDX6 peroxiredoxin 6 IMP (PMID:10893423) CAFA PMID:10893423 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
JBrowse link
G PRXL2A peroxiredoxin like 2A IEA GOC GO_REF:0000108 NCBI chr10:80,407,829...80,437,115
Ensembl chr10:80,407,829...80,437,115
JBrowse link
G PRXL2B peroxiredoxin like 2B IEA GOC GO_REF:0000108 NCBI chr 1:2,586,523...2,591,469
Ensembl chr 1:2,586,491...2,591,469
JBrowse link
G PRXL2C peroxiredoxin like 2C IEA GOC GO_REF:0000108 NCBI chr 9:96,639,577...96,655,331
Ensembl chr 9:96,639,577...96,655,317
JBrowse link
G PTGES prostaglandin E synthase IEA GOC GO_REF:0000108 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 IEA GOC GO_REF:0000108 NCBI chr 9:122,369,906...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IEA GOC GO_REF:0000108 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G PXDN peroxidasin IEA GOC GO_REF:0000108 NCBI chr 2:1,631,887...1,744,852
Ensembl chr 2:1,631,887...1,744,852
JBrowse link
G PXDNL peroxidasin like IEA GOC GO_REF:0000108 NCBI chr 8:51,319,575...51,809,445
Ensembl chr 8:51,319,577...51,809,445
JBrowse link
G RP1 RP1 axonemal microtubule associated IEA GOC GO_REF:0000108 NCBI chr 8:54,509,448...54,871,720
Ensembl chr 8:54,509,422...54,871,720
JBrowse link
G S100A9 S100 calcium binding protein A9 IEA GOC GO_REF:0000108 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
JBrowse link
G SELENOS selenoprotein S IEA GOC GO_REF:0000108 NCBI chr15:101,270,809...101,277,485
Ensembl chr15:101,270,817...101,277,500
JBrowse link
G SELENOT selenoprotein T ISS UniProtKB GO_REF:0000024 NCBI chr 3:150,603,321...150,630,436
Ensembl chr 3:150,602,875...150,630,445
JBrowse link
G SELENOW selenoprotein W IEA GOC GO_REF:0000108 NCBI chr19:47,778,703...47,784,682
Ensembl chr19:47,778,585...47,784,686
JBrowse link
G SESN1 sestrin 1 IMP (PMID:15105503) UniProtKB PMID:15105503 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,986,437...109,094,819
JBrowse link
G SESN2 sestrin 2 NOT IMP
IDA
(PMID:15105503)
(PMID:19113821)
(PMID:26612684)
UniProtKB PMID:15105503, PMID:19113821, PMID:26612684 NCBI chr 1:28,259,452...28,282,491
Ensembl chr 1:28,259,518...28,282,491
JBrowse link
G SRXN1 sulfiredoxin 1 IEA GOC GO_REF:0000108 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,370
Ensembl chr20:646,615...653,370
JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 IEA GOC GO_REF:0000108 NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378
JBrowse link
G TPO thyroid peroxidase IEA GOC GO_REF:0000108 NCBI chr 2:1,413,288...1,543,673
Ensembl chr 2:1,374,066...1,543,711
JBrowse link
G TXN thioredoxin IEA GOC GO_REF:0000108 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXNDC17 thioredoxin domain containing 17 IEA GOC GO_REF:0000108 NCBI chr17:6,641,060...6,644,541
Ensembl chr17:6,640,985...6,644,541
JBrowse link
G TXNDC2 thioredoxin domain containing 2 IEA GOC GO_REF:0000108 NCBI chr18:9,885,973...9,889,275
Ensembl chr18:9,885,726...9,889,275
JBrowse link
G TXNRD1 thioredoxin reductase 1 IEA GOC GO_REF:0000108 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G TXNRD2 thioredoxin reductase 2 IEA GOC GO_REF:0000108 NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820
JBrowse link
G TXNRD3 thioredoxin reductase 3 IEA GOC GO_REF:0000108 NCBI chr 3:126,607,050...126,655,124
Ensembl chr 3:126,607,059...126,655,124
JBrowse link
G UBIAD1 UbiA prenyltransferase domain containing 1 IEA GOC GO_REF:0000108 NCBI chr 1:11,273,198...11,299,574
Ensembl chr 1:11,273,198...11,296,049
Ensembl chr 1:11,273,198...11,296,049
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP7 bone morphogenetic protein 7 ISS BHF-UCL GO_REF:0000024 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G CD36 CD36 molecule IEA Ensembl GO_REF:0000107 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G DHFR dihydrofolate reductase ISS BHF-UCL GO_REF:0000024 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DHFRP1 dihydrofolate reductase pseudogene 1 ISS BHF-UCL GO_REF:0000024 NCBI chr18:26,167,862...26,171,357
Ensembl chr18:26,170,726...26,171,284
JBrowse link
G FBLN5 fibulin 5 ISS BHF-UCL GO_REF:0000024 NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,412...91,947,987
JBrowse link
G GCH1 GTP cyclohydrolase 1 IMP (PMID:19666465) BHF-UCL PMID:19666465 NCBI chr14:54,842,016...54,902,826
Ensembl chr14:54,842,008...54,902,826
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 IDA (PMID:16945374) HGNC PMID:16945374 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G ATP7A ATPase copper transporting alpha ISS UniProtKB GO_REF:0000024 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G CCS copper chaperone for superoxide dismutase IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr11:66,593,162...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G FANCC FA complementation group C IEA Ensembl GO_REF:0000107 NCBI chr 9:95,099,054...95,317,730
Ensembl chr 9:95,099,054...95,426,796
JBrowse link
G MPO myeloperoxidase IEA Ensembl GO_REF:0000107 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MT3 metallothionein 3 IDA (PMID:12383939) UniProtKB PMID:12383939 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G NOS3 nitric oxide synthase 3 IDA (PMID:19666465) BHF-UCL PMID:19666465 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 IEA GOC GO_REF:0000108 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PRDX1 peroxiredoxin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,511,036...45,523,047
JBrowse link
G PRDX2 peroxiredoxin 2 IDA
IBA
(PMID:20978343)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:20978343, PMID:21873635 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G SOD1 superoxide dismutase 1 IC
IBA
ISS
IEA
(PMID:24567322)
(PMID:21873635)
ParkinsonsUK-UCL
GO_Central
UniProtKB
GOC
PMID:21873635, PMID:24567322 GO_REF:0000024, GO_REF:0000108 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 IMP
IEA
(PMID:16179351) BHF-UCL
GOC
PMID:16179351 GO_REF:0000108 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:24,795,478...24,800,845
Ensembl chr 4:24,789,912...24,800,842
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    detoxification 140
      cellular detoxification 114
        cellular oxidant detoxification 100
          cellular detoxification of hydrogen peroxide 0
          removal of superoxide radicals + 20
Path 2
Term Annotations click to browse term
  biological_process 18670
    cellular process 17687
      cellular response to stimulus 8419
        cellular response to chemical stimulus 3965
          cellular response to toxic substance 127
            cellular detoxification 114
              cellular oxidant detoxification 100
                cellular detoxification of hydrogen peroxide 0
                removal of superoxide radicals + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.