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ONTOLOGY REPORT - ANNOTATIONS

Term:postsynaptic early endosome
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Accession:GO:0098842 term browser browse the term
Definition:An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.
Comment:Commonly used markers for postsynaptic early endosomes include RAB5A and EEA1.


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postsynaptic early endosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EEA1 early endosome antigen 1 is_active_in ISO (PMID:17113235), (PMID:34564930) SynGO PMID:17113235 PMID:34564930 NCBI chr 5:90,131,707...90,257,014
Ensembl chr 5:90,168,242...90,257,241 		JBrowse link
G PICK1 protein interacting with PRKCA 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,451...9,825,539 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family located_in
is_active_in		 ISO
IBA		 PMID:10930461 SynGO
GO_Central		 PMID:10930461 GO_REF:0000033 RGD:12050141 NCBI chr13:6,905,302...6,940,165
Ensembl chr13:6,905,390...6,941,423 		JBrowse link
G SNX27 sorting nexin 27 is_active_in ISO (PMID:24458027) SynGO PMID:24458027 NCBI chr 4:97,533,643...97,620,816
Ensembl chr 4:97,525,181...97,620,788 		JBrowse link
G SNX6 sorting nexin 6 is_active_in ISO (PMID:28134614) SynGO PMID:28134614 NCBI chr 7:65,156,476...65,205,249
Ensembl chr 7:65,156,478...65,205,239 		JBrowse link
G VPS26B VPS26, retromer complex component B is_active_in ISO (PMID:34965419) SynGO PMID:34965419 NCBI chr 9:60,786,192...60,802,507
Ensembl chr 9:60,785,998...60,805,193 		JBrowse link
extrinsic component of postsynaptic early endosome membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIPAP1 GRIP1 associated protein 1 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:43,043,613...43,070,363
Ensembl chr  X:43,043,029...43,070,364 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18685
    cellular anatomical entity 18463
      postsynapse 923
        postsynaptic endosome 26
          postsynaptic early endosome 7
            postsynaptic early endosome membrane + 1
Path 2
Term Annotations click to browse term
  cellular_component 18685
    cellular anatomical entity 18463
      organelle 12421
        membrane-bounded organelle 11396
          intracellular membrane-bounded organelle 10852
            intracellular vesicle 1903
              cytoplasmic vesicle 1894
                endosome 905
                  postsynaptic endosome 26
                    postsynaptic early endosome 7
                      postsynaptic early endosome membrane + 1
paths to the root