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ONTOLOGY REPORT - ANNOTATIONS


Term:spontaneous synaptic transmission
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Accession:GO:0098814 term browser browse the term
Definition:The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.
Comment:This is typically measured via detection of mini excitatory post-synaptic currents (mEPSCs).
Synonyms:exact_synonym: basal synaptic transmission


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spontaneous synaptic transmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbln2 cerebellin 2 precursor ISO (MGI:MGI:6220615|PMID:30287486) UniProt PMID:30287486 MGI:MGI:6220615 NCBI chrNW_004955402:56,052,340...56,062,190
Ensembl chrNW_004955402:56,051,496...56,062,190
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 ISO PMID:15911354 UniProt PMID:15911354 RGD:9850096 NCBI chrNW_004955514:5,273,810...5,294,925
Ensembl chrNW_004955514:5,273,810...5,295,710
JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9a protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:16899074 RGD:10002752 NCBI chrNW_004955432:11,607,269...11,891,568
Ensembl chrNW_004955432:11,608,382...11,886,044
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152
JBrowse link
positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B ISO (MGI:MGI:5603022|PMID:24587181) ParkinsonsUK-UCL PMID:24587181 MGI:MGI:5603022 NCBI chrNW_004955493:7,838,684...7,857,700
Ensembl chrNW_004955493:7,838,684...7,857,700
JBrowse link
regulation of spontaneous synaptic transmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO (PMID:15457210) ARUK-UCL PMID:15457210 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G App amyloid beta precursor protein ISO (PMID:15457210) ARUK-UCL PMID:15457210 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
G Itgb1 integrin subunit beta 1 ISO (MGI:MGI:5629870|PMID:25716834) ARUK-UCL PMID:25716834 MGI:MGI:5629870 NCBI chrNW_004955462:4,454,809...4,483,227
Ensembl chrNW_004955462:4,454,809...4,484,842
JBrowse link
G Slc12a2 solute carrier family 12 member 2 ISO (MGI:MGI:3608187|PMID:16227993)
(MGI:MGI:5629870|PMID:25716834)
ARUK-UCL PMID:16227993, PMID:25716834 MGI:MGI:3608187, MGI:MGI:5629870, RGD:1580584 NCBI chrNW_004955415:1,138,297...1,219,241
Ensembl chrNW_004955415:1,137,327...1,219,241
JBrowse link
spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Doc2a double C2 domain alpha ISO (MGI:MGI:5141208|PMID:21521611) MGI PMID:21521611 MGI:MGI:5141208 NCBI chrNW_004955493:6,948,089...6,953,835
Ensembl chrNW_004955493:6,947,512...6,953,835
JBrowse link
G Doc2b double C2 domain beta ISO (MGI:MGI:5141208|PMID:21521611) MGI PMID:21521611 MGI:MGI:5141208 NCBI chrNW_004955481:1,839,894...1,859,733
Ensembl chrNW_004955481:1,842,815...1,860,374
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 ISO (MGI:MGI:4887275|PMID:21262469) ParkinsonsUK-UCL PMID:21262469 MGI:MGI:4887275 NCBI chrNW_004955488:6,999,128...7,196,583
Ensembl chrNW_004955488:6,936,952...7,197,022
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO (MGI:MGI:4887275|PMID:21262469) ParkinsonsUK-UCL PMID:21262469 MGI:MGI:4887275 NCBI chrNW_004955417:27,748,090...28,131,431
Ensembl chrNW_004955417:27,728,428...28,128,877
JBrowse link
G Rph3a rabphilin 3A ISO (MGI:MGI:5141208|PMID:21521611) MGI PMID:21521611 MGI:MGI:5141208 NCBI chrNW_004955482:9,190,137...9,312,596
Ensembl chrNW_004955482:9,225,845...9,312,695
JBrowse link
G Stx1b syntaxin 1B ISO (MGI:MGI:3803800|PMID:18703708)
(MGI:MGI:5521403|PMID:24133272)
ParkinsonsUK-UCL PMID:18703708, PMID:24133272 MGI:MGI:3803800, MGI:MGI:5521403 NCBI chrNW_004955493:7,838,684...7,857,700
Ensembl chrNW_004955493:7,838,684...7,857,700
JBrowse link
G Syt1 synaptotagmin 1 ISO (MGI:MGI:5141208|PMID:21521611) MGI PMID:21521611 MGI:MGI:5141208 NCBI chrNW_004955405:17,840,012...18,372,156
Ensembl chrNW_004955405:17,839,884...18,372,566
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    signaling 4144
      cell-cell signaling 1348
        synaptic signaling 653
          trans-synaptic signaling 633
            anterograde trans-synaptic signaling 626
              chemical synaptic transmission 626
                spontaneous synaptic transmission 15
                  regulation of spontaneous synaptic transmission + 7
                  spontaneous neurotransmitter secretion + 9
Path 2
Term Annotations click to browse term
  biological_process 11892
    cellular process 11094
      cell communication 4210
        cell-cell signaling 1348
          synaptic signaling 653
            trans-synaptic signaling 633
              anterograde trans-synaptic signaling 626
                chemical synaptic transmission 626
                  spontaneous synaptic transmission 15
                    regulation of spontaneous synaptic transmission + 7
                    spontaneous neurotransmitter secretion + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.