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ONTOLOGY REPORT - ANNOTATIONS

Term:spontaneous synaptic transmission
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Accession:GO:0098814 term browser browse the term
Definition:The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.
Comment:This is typically measured via detection of mini excitatory post-synaptic currents (mEPSCs).
Synonyms:exact_synonym: basal synaptic transmission


show annotations for term's descendants           Sort by:
spontaneous synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbln2 cerebellin 2 precursor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:30287486) 		UniProt
Ensembl
RGD		 PMID:30287486 GO_REF:0000024 GO_REF:0000107 NCBI chr18:79,940,412...79,948,766
Ensembl chr18:79,942,590...79,947,855 		JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 involved_in IMP PMID:15911354 UniProt PMID:15911354 RGD:9850096 NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514 		JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:16899074 RGD:10002752 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA 		(PMID:22314364)
GO_REF:0000107 		RGD
Ensembl		 PMID:22314364 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B involved_in IEA
ISO 		GO_REF:0000107
(PMID:24587181) 		Ensembl
RGD		 PMID:24587181 GO_REF:0000107 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
regulation of spontaneous synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA 		UniProtKB:P05067 (PMID:15457210)
GO_REF:0000107 		RGD
Ensembl		 PMID:15457210 GO_REF:0000107 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G App amyloid beta precursor protein involved_in ISO
IEA 		UniProtKB:Q15109 (PMID:15457210)
GO_REF:0000107 		RGD
Ensembl		 PMID:15457210 GO_REF:0000107 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within_negative_effect ISO (PMID:25716834) RGD PMID:25716834 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within IMP
ISO 		PMID:16227993
UniProtKB:P09055 (PMID:16227993), (PMID:25716834) 		RGD PMID:16227993 PMID:25716834 PMID:16227993 RGD:1580584 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Doc2a double C2 domain alpha acts_upstream_of_or_within ISO
IEA 		MGI:102788|MGI:1100497|MGI:1926250 (PMID:21521611)
GO_REF:0000107 		RGD
Ensembl		 PMID:21521611 GO_REF:0000107 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030 		JBrowse link
G Doc2b double C2 domain beta acts_upstream_of_or_within ISO
IEA 		MGI:102788|MGI:109446|MGI:1926250 (PMID:21521611)
GO_REF:0000107 		RGD
Ensembl		 PMID:21521611 GO_REF:0000107 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (PMID:21262469) RGD PMID:21262469 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISS
ISO 		GO_REF:0000024
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (PMID:21262469) 		ParkinsonsUK-UCL
RGD		 PMID:21262469 GO_REF:0000024 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Rph3a rabphilin 3A acts_upstream_of_or_within ISO
IEA 		MGI:109446|MGI:1100497|MGI:1926250 (PMID:21521611)
GO_REF:0000107 		RGD
Ensembl		 PMID:21521611 GO_REF:0000107 NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592 		JBrowse link
G Stx1b syntaxin 1B involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:O35526 (PMID:18703708), (PMID:24133272) 		Ensembl
RGD		 PMID:18703708 PMID:24133272 GO_REF:0000107 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Syt1 synaptotagmin 1 acts_upstream_of_or_within ISO
IEA 		MGI:1857252 (PMID:21521611)
GO_REF:0000107 		RGD
Ensembl		 PMID:21521611 GO_REF:0000107 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
G Unc13b unc-13 homolog B involved_in IGI PMID:21262469 ParkinsonsUK-UCL PMID:21262469 RGD:10047275 NCBI chr 5:62,084,809...62,299,884
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cell communication 7907
        cell-cell signaling 1491
          synaptic signaling 1011
            trans-synaptic signaling 967
              anterograde trans-synaptic signaling 959
                chemical synaptic transmission 959
                  spontaneous synaptic transmission 16
                    regulation of spontaneous synaptic transmission + 7
                    spontaneous neurotransmitter secretion + 10
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        signaling 7874
          cell-cell signaling 1491
            synaptic signaling 1011
              trans-synaptic signaling 967
                anterograde trans-synaptic signaling 959
                  chemical synaptic transmission 959
                    spontaneous synaptic transmission 16
                      regulation of spontaneous synaptic transmission + 7
                      spontaneous neurotransmitter secretion + 10
paths to the root