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ONTOLOGY REPORT - ANNOTATIONS


Term:spontaneous synaptic transmission
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Accession:GO:0098814 term browser browse the term
Definition:The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.
Comment:This is typically measured via detection of mini excitatory post-synaptic currents (mEPSCs).
Synonyms:exact_synonym: basal synaptic transmission


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spontaneous synaptic transmission term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbln2 cerebellin 2 precursor JBrowse link 18 83,775,568 83,783,841 RGD:1600115
RGD:1624291
G Nsg1 neuronal vesicle trafficking associated 1 JBrowse link 14 77,380,264 77,402,007 RGD:9850096
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:10002752
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1624291
regulation of spontaneous synaptic transmission term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1624291
RGD:1600115
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1600115
RGD:1624291
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1580584
RGD:1624291
spontaneous neurotransmitter secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Doc2a double C2 domain alpha JBrowse link 1 198,282,828 198,288,611 RGD:1624291
G Doc2b double C2 domain beta JBrowse link 10 63,921,255 63,952,944 RGD:1600115
RGD:1624291
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:1600115
G Rph3a rabphilin 3A JBrowse link 12 41,073,296 41,149,799 RGD:1600115
RGD:1624291
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1624291
G Syt1 synaptotagmin 1 JBrowse link 7 50,084,063 50,638,996 RGD:1624291
G Unc13b unc-13 homolog B JBrowse link 5 58,505,449 58,714,396 RGD:10047275

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      cell-cell signaling 1794
        synaptic signaling 913
          trans-synaptic signaling 885
            anterograde trans-synaptic signaling 876
              chemical synaptic transmission 876
                spontaneous synaptic transmission 16
                  regulation of spontaneous synaptic transmission + 7
                  spontaneous neurotransmitter secretion + 10
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cell communication 7631
        cell-cell signaling 1794
          synaptic signaling 913
            trans-synaptic signaling 885
              anterograde trans-synaptic signaling 876
                chemical synaptic transmission 876
                  spontaneous synaptic transmission 16
                    regulation of spontaneous synaptic transmission + 7
                    spontaneous neurotransmitter secretion + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.