bone cell development - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS	{{ watchLinkText }}

Term:	bone cell development	go back to main search page
Accession:	GO:0098751	browse the term
Definition:	The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Comment:	Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.

show annotations for term's descendants Sort by:
Rat (20) Mouse (19) Human (21) Chinchilla (18) Bonobo (19) Dog (19) Squirrel (18) Pig (19) Green Monkey (19) Naked Mole-rat (18) All
Genes (20)

negative regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cldn18

claudin 18

acts_upstream_of_or_within

ISO

MGI:5007067 (MGI:5489769|PMID:22437732)

RGD

PMID:22437732

MGI:5489769

NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351

Fbn1

fibrillin 1

involved_in

ISO

(PMID:24039232)
(MGI:5795811|PMID:24039232)

RGD

PMID:24039232

MGI:5795811

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

Fbxw7

F-box and WD repeat domain containing 7

involved_in

ISO

(PMID:29149593)
(MGI:6106664|PMID:29149593)

RGD

PMID:29149593

MGI:6106664

NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941

Tjp2

tight junction protein 2

acts_upstream_of_or_within

ISO

(MGI:5489769|PMID:22437732)

RGD

PMID:22437732

MGI:5489769

NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295

osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa2

annexin A2

involved_in

ISO
IEA

(PMID:7961821)
GO_REF:0000107

RGD
Ensembl

PMID:7961821

GO_REF:0000107

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

Atp6ap1

ATPase H+ transporting accessory protein 1

involved_in

ISO
IEA
ISS

(MGI:5575464|PMID:22467241)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
CAFA

PMID:22467241

GO_REF:0000024 GO_REF:0000107 MGI:5575464

NCBI chr X:152,079,954...152,087,034
Ensembl chr X:152,079,865...152,087,034

Foxp1

forkhead box P1

involved_in

ISO

(PMID:18799727)

RGD

PMID:18799727

NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258

Gpr68

G protein-coupled receptor 68

acts_upstream_of

ISO

MGI:3849457 (MGI:3848292|PMID:19479052)

RGD

PMID:19479052

MGI:3848292

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

Lrrk1

leucine-rich repeat kinase 1

acts_upstream_of_or_within

ISO

MGI:5568128|MGI:98397 (MGI:5564766|PMID:23526378)

RGD

PMID:23526378

MGI:5564766

NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734

Mir34a

microRNA 34a

acts_upstream_of_or_within_negative_effect

ISO

(MGI:5613071|PMID:25043055)

RGD

PMID:25043055

MGI:5613071

NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103

Pafah1b1

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

acts_upstream_of_or_within

ISO

(MGI:5308511|PMID:22073305)

RGD

PMID:22073305

MGI:5308511

NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808

Ptprv

protein tyrosine phosphatase, receptor type, V

IEP

RGD

PMID:7527035

RGD:632779

NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329

Src

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in
acts_upstream_of_or_within

IBA
ISO

PMID:21873635
MGI:2142227 (MGI:5564766|PMID:23526378)

RGD

PMID:23526378 PMID:21873635

MGI:5564766, RGD:13792537

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

Tnfsf11

TNF superfamily member 11

acts_upstream_of_or_within
involved_in

ISO
IEA

(MGI:5297759|PMID:21841309)
GO_REF:0000107

RGD
Ensembl

PMID:21841309

GO_REF:0000107 MGI:5297759

NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445

osteoclast maturation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fam20c

FAM20C, golgi associated secretory pathway kinase

acts_upstream_of_or_within

ISO

MGI:2656539|MGI:5428020 (MGI:5427766|PMID:22615579)

RGD

PMID:22615579

MGI:5427766

NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543

positive regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gpr68

G protein-coupled receptor 68

acts_upstream_of_or_within

ISO

MGI:3849457 (MGI:3848292|PMID:19479052)

RGD

PMID:19479052

MGI:3848292

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

Ninj1

ninjurin 1

involved_in

ISO

(MGI:6458683|PMID:30700695)

RGD

PMID:30700695

MGI:6458683

NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704

Slc9b2

solute carrier family 9 member B2

acts_upstream_of_or_within

ISO

(MGI:3785147|PMID:18269914)

RGD

PMID:18269914

MGI:3785147

NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225

Tnfsf11

TNF superfamily member 11

acts_upstream_of_or_within
involved_in

ISO
IEA

(MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096)
GO_REF:0000107

RGD
Ensembl

PMID:18269914 PMID:22437732 PMID:23980096

GO_REF:0000107 MGI:3785147 MGI:5489769 MGI:5522615

NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445

Tyrobp

transmembrane immune signaling adaptor Tyrobp

involved_in

ISO

(MGI:3653295|PMID:14969392)

RGD

PMID:14969392

MGI:3653295

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Notch2

notch receptor 2

involved_in

ISO
IEA
ISS

(PMID:29149593)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:29149593

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

Siglec15

sialic acid binding Ig-like lectin 15

involved_in
acts_upstream_of_or_within

IBA
ISO

PMID:21873635
MGI:1277211 (MGI:5467208|PMID:22451653)

RGD

PMID:22451653 PMID:21873635

MGI:5467208, RGD:13792537

NCBI chr18:71,507,773...71,521,722
Ensembl chr18:71,505,399...71,521,881

Tyrobp

transmembrane immune signaling adaptor Tyrobp

acts_upstream_of_or_within

ISO

MGI:3646642 (MGI:5467208|PMID:22451653)

RGD

PMID:22451653

MGI:5467208

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

Term paths to the root

Path 1
Term	Annotations
biological_process	19818
developmental process	6893
cellular developmental process	4651
cell development	3225
bone cell development	20
osteoclast development +	20
Path 2
Term	Annotations
biological_process	19818
developmental process	6893
anatomical structure development	6417
multicellular organism development	5169
system development	4449
skeletal system development	570
bone development	258
bone cell development	20
osteoclast development +	20

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ONTOLOGY REPORT - ANNOTATIONS