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ONTOLOGY REPORT - ANNOTATIONS

Term:bone cell development
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Accession:GO:0098751 term browser browse the term
Definition:The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Comment:Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.
Synonyms:synonym: Not4Curation


show annotations for term's descendants           Sort by:
 
megakaryocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3847627|PMID:17664349)		 Ensembl
RGD		 PMID:17664349 GO_REF:0000107 MGI:3847627 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Ep300 E1A binding protein p300 acts_upstream_of_or_within ISO MGI:3813243 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor acts_upstream_of_or_within ISO MGI:2386167 (MGI:3808108|PMID:16757682) RGD PMID:16757682 MGI:3808108 NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:3040777|PMID:15067126) RGD PMID:15067126 MGI:3040777 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2158098|PMID:11724781)		 UniProt
RGD		 PMID:11724781 GO_REF:0000024 MGI:2158098 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Meis1 Meis homeobox 1 acts_upstream_of_or_within ISO MGI:3578637 (MGI:4948219|PMID:20203303) RGD PMID:20203303 MGI:4948219 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 GO_REF:0000107
MGI:2675830 (MGI:5512895|PMID:23112346)
PMID:21873635
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23112346 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5512895, RGD:13792537 NCBI chr20:3,757,396...3,761,024
Ensembl chr20:3,757,536...3,760,735 		JBrowse link
G Nbeal2 neurobeachin-like 2 acts_upstream_of_or_within ISO MGI:4461705|MGI:5007262 (MGI:5528579|PMID:23861251), (MGI:5636146|PMID:25258341) RGD PMID:23861251 PMID:25258341 MGI:5528579 MGI:5636146 NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707 		JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO
IEA		 (MGI:3776733|PMID:16434494)
GO_REF:0000107		 RGD
Ensembl		 PMID:16434494 GO_REF:0000107 MGI:3776733 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:3690333 (MGI:5494903|PMID:23509158) RGD PMID:23509158 MGI:5494903 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3719625 (MGI:5494903|PMID:23509158)		 Ensembl
RGD		 PMID:23509158 GO_REF:0000107 MGI:5494903 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3510267|PMID:15337790)		 Ensembl
RGD		 PMID:15337790 GO_REF:0000107 MGI:3510267 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922), (MGI:4848276|PMID:20709909) RGD PMID:20525922 PMID:20709909 MGI:4834086 MGI:4848276 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1858004|MGI:2450743 (MGI:3808106|PMID:16763211) RGD PMID:16763211 MGI:3808106 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976 		JBrowse link
G Tesc tescalcin NOT|involved_in ISO (MGI:5315196|PMID:22285131) RGD PMID:22285131 MGI:5315196 NCBI chr12:38,521,839...38,555,665
Ensembl chr12:38,521,861...38,555,824 		JBrowse link
G Thpo thrombopoietin involved_in ISO (PMID:15337790) RGD PMID:15337790 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated involved_in ISO (MGI:5645581|PMID:25947942) RGD PMID:25947942 MGI:5645581 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970 		JBrowse link
G Wasf2 WASP family member 2 acts_upstream_of_or_within ISO (MGI:3847627|PMID:17664349) RGD PMID:17664349 MGI:3847627 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
G Zfp385a zinc finger protein 385A acts_upstream_of_or_within ISO MGI:3510440 (MGI:3505817|PMID:11927637) RGD PMID:11927637 MGI:3505817 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 acts_upstream_of_or_within ISO MGI:2176182|MGI:4421436 (MGI:4420713|PMID:20010697) RGD PMID:20010697 MGI:4420713 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)		 RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:29149593)
(MGI:6106664|PMID:29149593)		 RGD PMID:29149593 MGI:6106664 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:7961821) RGD PMID:7961821 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO
IEA
ISS		 (MGI:5575464|PMID:22467241)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
CAFA		 PMID:22467241 GO_REF:0000024 GO_REF:0000107 MGI:5575464 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of
involved_in		 ISO
IEA		 MGI:3849457 (MGI:3848292|PMID:19479052)
GO_REF:0000107		 RGD
Ensembl		 PMID:19479052 GO_REF:0000107 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 acts_upstream_of_or_within ISO MGI:5568128|MGI:98397 (MGI:5564766|PMID:23526378) RGD PMID:23526378 MGI:5564766 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734 		JBrowse link
G Mir34a microRNA 34a acts_upstream_of_or_within_negative_effect ISO (MGI:5613071|PMID:25043055) RGD PMID:25043055 MGI:5613071 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IEP RGD PMID:7527035 RGD:632779 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2142227 (MGI:5564766|PMID:23526378)		 RGD PMID:23526378 PMID:21873635 MGI:5564766, RGD:13792537 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5297759|PMID:21841309)
GO_REF:0000107		 RGD
Ensembl		 PMID:21841309 GO_REF:0000107 MGI:5297759 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
osteoclast maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO MGI:2656539|MGI:5428020 (MGI:5427766|PMID:22615579) RGD PMID:22615579 MGI:5427766 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6458683|PMID:30700695) RGD PMID:30700695 MGI:6458683 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Slc9b2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914) RGD PMID:18269914 MGI:3785147 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096)
GO_REF:0000107		 RGD
Ensembl		 PMID:18269914 PMID:22437732 PMID:23980096 GO_REF:0000107 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3653295|PMID:14969392) RGD PMID:14969392 MGI:3653295 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch2 notch receptor 2 involved_in ISO
IEA
ISS		 (PMID:29149593)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29149593 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1277211 (MGI:5467208|PMID:22451653)		 RGD PMID:22451653 PMID:21873635 MGI:5467208, RGD:13792537 NCBI chr18:71,507,773...71,521,722
Ensembl chr18:71,505,399...71,521,881 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp acts_upstream_of_or_within ISO MGI:3646642 (MGI:5467208|PMID:22451653) RGD PMID:22451653 MGI:5467208 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      cellular developmental process 4534
        cell development 2536
          bone cell development 44
            megakaryocyte development 24
            osteoclast development + 20
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        multicellular organism development 5440
          system development 4941
            skeletal system development 582
              bone development 278
                bone cell development 44
                  megakaryocyte development 24
                  osteoclast development + 20
paths to the root