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ONTOLOGY REPORT - ANNOTATIONS


Term:bone cell development
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Accession:GO:0098751 term browser browse the term
Definition:The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Comment:Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.
Synonyms:synonym: Not4Curation



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megakaryocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3847627|PMID:17664349)
Ensembl
RGD
PMID:17664349 GO_REF:0000107 MGI:3847627 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
JBrowse link
G Ep300 E1A binding protein p300 acts_upstream_of_or_within ISO MGI:3813243 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor acts_upstream_of_or_within ISO MGI:2386167 (MGI:3808108|PMID:16757682) RGD PMID:16757682 MGI:3808108 NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO (MGI:3773462|PMID:18187573) RGD PMID:18187573 MGI:3773462 NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:3040777|PMID:15067126) RGD PMID:15067126 MGI:3040777 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2158098|PMID:11724781)
UniProt
RGD
PMID:11724781 GO_REF:0000024 MGI:2158098 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Meis1 Meis homeobox 1 acts_upstream_of_or_within ISO MGI:3578637 (MGI:4948219|PMID:20203303) RGD PMID:20203303 MGI:4948219 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
ISS
GO_REF:0000107
MGI:2675830 (MGI:5512895|PMID:23112346)
PMID:21873635
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23112346 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5512895, RGD:13792537 NCBI chr20:3,757,396...3,761,024
Ensembl chr20:3,757,536...3,760,735
JBrowse link
G Nbeal2 neurobeachin-like 2 acts_upstream_of_or_within ISO MGI:4461705|MGI:5007262 (MGI:5528579|PMID:23861251), (MGI:5636146|PMID:25258341) RGD PMID:23861251 PMID:25258341 MGI:5528579 MGI:5636146 NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO
IEA
(MGI:3776733|PMID:16434494)
GO_REF:0000107
RGD
Ensembl
PMID:16434494 GO_REF:0000107 MGI:3776733 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:3690333 (MGI:5494903|PMID:23509158) RGD PMID:23509158 MGI:5494903 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3719625 (MGI:5494903|PMID:23509158)
Ensembl
RGD
PMID:23509158 GO_REF:0000107 MGI:5494903 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3510267|PMID:15337790)
Ensembl
RGD
PMID:15337790 GO_REF:0000107 MGI:3510267 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922), (MGI:4848276|PMID:20709909) RGD PMID:20525922 PMID:20709909 MGI:4834086 MGI:4848276 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1858004|MGI:2450743 (MGI:3808106|PMID:16763211) RGD PMID:16763211 MGI:3808106 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Tesc tescalcin NOT|involved_in ISO (MGI:5315196|PMID:22285131) RGD PMID:22285131 MGI:5315196 NCBI chr12:38,521,839...38,555,665
Ensembl chr12:38,521,861...38,555,824
JBrowse link
G Thpo thrombopoietin involved_in ISO (PMID:15337790) RGD PMID:15337790 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated involved_in ISO (MGI:5645581|PMID:25947942) RGD PMID:25947942 MGI:5645581 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970
JBrowse link
G Wasf2 WASP family member 2 acts_upstream_of_or_within ISO (MGI:3847627|PMID:17664349) RGD PMID:17664349 MGI:3847627 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Zfp385a zinc finger protein 385A acts_upstream_of_or_within ISO MGI:3510440 (MGI:3505817|PMID:11927637) RGD PMID:11927637 MGI:3505817 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 acts_upstream_of_or_within ISO MGI:2176182|MGI:4421436 (MGI:4420713|PMID:20010697) RGD PMID:20010697 MGI:4420713 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)
RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:29149593)
(MGI:6106664|PMID:29149593)
RGD PMID:29149593 MGI:6106664 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:7961821) RGD PMID:7961821 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO
IEA
ISS
(MGI:5575464|PMID:22467241)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
CAFA
PMID:22467241 GO_REF:0000024 GO_REF:0000107 MGI:5575464 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034
JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of
involved_in
ISO
IEA
MGI:3849457 (MGI:3848292|PMID:19479052)
GO_REF:0000107
RGD
Ensembl
PMID:19479052 GO_REF:0000107 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 acts_upstream_of_or_within ISO MGI:5568128|MGI:98397 (MGI:5564766|PMID:23526378) RGD PMID:23526378 MGI:5564766 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
JBrowse link
G Mir34a microRNA 34a acts_upstream_of_or_within_negative_effect ISO (MGI:5613071|PMID:25043055) RGD PMID:25043055 MGI:5613071 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IEP RGD PMID:7527035 RGD:632779 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2142227 (MGI:5564766|PMID:23526378)
RGD PMID:23526378 PMID:21873635 MGI:5564766, RGD:13792537 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5297759|PMID:21841309)
GO_REF:0000107
RGD
Ensembl
PMID:21841309 GO_REF:0000107 MGI:5297759 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
osteoclast maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO MGI:2656539|MGI:5428020 (MGI:5427766|PMID:22615579) RGD PMID:22615579 MGI:5427766 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6458683|PMID:30700695) RGD PMID:30700695 MGI:6458683 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Slc9b2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914) RGD PMID:18269914 MGI:3785147 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096)
GO_REF:0000107
RGD
Ensembl
PMID:18269914 PMID:22437732 PMID:23980096 GO_REF:0000107 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3653295|PMID:14969392) RGD PMID:14969392 MGI:3653295 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch2 notch receptor 2 involved_in ISO
IEA
ISS
(PMID:29149593)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:29149593 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1277211 (MGI:5467208|PMID:22451653)
RGD PMID:22451653 PMID:21873635 MGI:5467208, RGD:13792537 NCBI chr18:71,507,773...71,521,722
Ensembl chr18:71,505,399...71,521,881
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp acts_upstream_of_or_within ISO MGI:3646642 (MGI:5467208|PMID:22451653) RGD PMID:22451653 MGI:5467208 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      cellular developmental process 4534
        cell development 2536
          bone cell development 44
            megakaryocyte development 24
            osteoclast development + 20
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        multicellular organism development 5440
          system development 4941
            skeletal system development 582
              bone development 278
                bone cell development 44
                  megakaryocyte development 24
                  osteoclast development + 20
paths to the root