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ONTOLOGY REPORT - ANNOTATIONS


Term:bone cell development
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Accession:GO:0098751 term browser browse the term
Definition:The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Comment:Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.


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megakaryocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 IEA
ISO
GO_REF:0000107
(MGI:3847627|PMID:17664349)
Ensembl
RGD
PMID:17664349 GO_REF:0000107 MGI:3847627 NCBI chr17:89,951,662...90,033,334
Ensembl chr17:89,951,752...90,033,328
JBrowse link
G Ep300 E1A binding protein p300 ISO MGI:3813243 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor ISO MGI:2386167 (MGI:3808108|PMID:16757682) RGD PMID:16757682 MGI:3808108 NCBI chr 8:33,541,932...33,661,111
Ensembl chr 8:33,543,258...33,661,049
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO (MGI:3040777|PMID:15067126) RGD PMID:15067126 MGI:3040777 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Med1 mediator complex subunit 1 ISS
ISO
GO_REF:0000024
(MGI:2158098|PMID:11724781)
UniProt
RGD
PMID:11724781 GO_REF:0000024 MGI:2158098 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Meis1 Meis homeobox 1 ISO MGI:3578637 (MGI:4948219|PMID:20203303) RGD PMID:20203303 MGI:4948219 NCBI chr14:103,182,178...103,321,809
Ensembl chr14:103,181,281...103,321,270
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
MGI:2675830 (MGI:5512895|PMID:23112346)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23112346, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5512895, RGD:13792537 NCBI chr20:5,054,419...5,056,655
Ensembl chr20:5,054,583...5,056,488
JBrowse link
G Nbeal2 neurobeachin-like 2 ISO MGI:4461705|MGI:5007262 (MGI:5528579|PMID:23861251), (MGI:5636146|PMID:25258341) RGD PMID:23861251 PMID:25258341 MGI:5528579 MGI:5636146 NCBI chr 8:118,893,987...118,924,390
Ensembl chr 8:118,893,995...118,926,613
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO (MGI:3776733|PMID:16434494) RGD PMID:16434494 MGI:3776733 NCBI chr17:85,533,056...85,748,843 JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO MGI:3690333 (MGI:5494903|PMID:23509158) RGD PMID:23509158 MGI:5494903 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA
ISO
GO_REF:0000107
MGI:3719625 (MGI:5494903|PMID:23509158)
Ensembl
RGD
PMID:23509158 GO_REF:0000107 MGI:5494903 NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
JBrowse link
G Sh2b3 SH2B adaptor protein 3 IEA
ISO
GO_REF:0000107
(MGI:3510267|PMID:15337790)
Ensembl
RGD
PMID:15337790 GO_REF:0000107 MGI:3510267 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Srf serum response factor ISO MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922), (MGI:4848276|PMID:20709909) RGD PMID:20525922 PMID:20709909 MGI:4834086 MGI:4848276 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor ISO MGI:1858004|MGI:2450743 (MGI:3808106|PMID:16763211) RGD PMID:16763211 MGI:3808106 NCBI chr 5:133,864,401...133,878,604
Ensembl chr 5:133,864,798...133,878,830
JBrowse link
G Tesc tescalcin NOT ISO (MGI:5315196|PMID:22285131) RGD PMID:22285131 MGI:5315196 NCBI chr12:44,141,258...44,174,701
Ensembl chr12:44,141,422...44,174,583
JBrowse link
G Thpo thrombopoietin ISO (PMID:15337790) RGD PMID:15337790 NCBI chr11:82,845,676...82,853,439
Ensembl chr11:83,868,655...83,873,910
Ensembl chr11:83,868,655...83,873,910
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated ISO (MGI:5645581|PMID:25947942) RGD PMID:25947942 MGI:5645581 NCBI chr 1:142,060,955...142,083,955
Ensembl chr 1:142,060,955...142,083,953
JBrowse link
G Wasf2 WASP family member 2 ISO (MGI:3847627|PMID:17664349) RGD PMID:17664349 MGI:3847627 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238
JBrowse link
G Zfp385a zinc finger protein 385A ISO MGI:3510440 (MGI:3505817|PMID:11927637) RGD PMID:11927637 MGI:3505817 NCBI chr 7:144,939,616...144,966,364
Ensembl chr 7:144,939,619...144,966,370
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 ISO MGI:2176182|MGI:4421436 (MGI:4420713|PMID:20010697) RGD PMID:20010697 MGI:4420713 NCBI chr19:55,094,585...55,150,994
Ensembl chr19:55,094,585...55,150,686
JBrowse link
negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 ISO MGI:5007067 (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 8:107,933,725...107,960,656
Ensembl chr 8:107,934,860...107,952,530
JBrowse link
G Fbn1 fibrillin 1 ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)
RGD PMID:24039232 MGI:5795811 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO (PMID:29149593)
(MGI:6106664|PMID:29149593)
RGD PMID:29149593 MGI:6106664 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Tjp2 tight junction protein 2 ISO (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 ISO (PMID:7961821) RGD PMID:7961821 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Foxp1 forkhead box P1 ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 ISO MGI:5568128|MGI:98397 (MGI:5564766|PMID:23526378) RGD PMID:23526378 MGI:5564766 NCBI chr 1:127,166,866...127,301,053
Ensembl chr 1:127,166,431...127,292,090
JBrowse link
G Mir34a microRNA 34a ISO (MGI:5613071|PMID:25043055) RGD PMID:25043055 MGI:5613071 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 ISO (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO
IBA
MGI:2142227 (MGI:5564766|PMID:23526378)
PMID:21873635
RGD PMID:23526378, PMID:21873635 MGI:5564766, RGD:13792537 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO (MGI:5297759|PMID:21841309) RGD PMID:21841309 MGI:5297759 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
osteoclast maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam20c FAM20C, golgi associated secretory pathway kinase ISO MGI:2656539|MGI:5428020 (MGI:5427766|PMID:22615579) RGD PMID:22615579 MGI:5427766 NCBI chr12:17,913,771...17,972,733
Ensembl chr12:17,913,767...17,972,737
JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap1 ATPase H+ transporting accessory protein 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:5575464|PMID:22467241)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22467241 GO_REF:0000024 GO_REF:0000107 MGI:5575464 NCBI chr  X:156,407,973...156,415,053
Ensembl chr  X:156,407,937...156,415,145
JBrowse link
G Gpr68 G protein-coupled receptor 68 ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:124,874,151...124,903,949
Ensembl chr 6:124,874,151...124,876,710
JBrowse link
G Slc9b2 solute carrier family 9 member B2 ISO (MGI:3785147|PMID:18269914) RGD PMID:18269914 MGI:3785147 NCBI chr 2:240,485,254...240,519,166
Ensembl chr 2:240,495,371...240,519,141
JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO (MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096) RGD PMID:18269914 PMID:22437732 PMID:23980096 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp ISO (MGI:3653295|PMID:14969392) RGD PMID:14969392 MGI:3653295 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch2 notch receptor 2 ISS
ISO
IEA
GO_REF:0000024
(PMID:29149593)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29149593 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 ISO
IBA
MGI:1277211 (MGI:5467208|PMID:22451653)
PMID:21873635
RGD PMID:22451653, PMID:21873635 MGI:5467208, RGD:13792537 NCBI chr18:74,403,384...74,417,333
Ensembl chr18:74,403,384...74,417,333
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp ISO MGI:3646642 (MGI:5467208|PMID:22451653) RGD PMID:22451653 MGI:5467208 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        cell development 2447
          bone cell development 38
            megakaryocyte development 20
            osteoclast development + 18
Path 2
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        multicellular organism development 5766
          system development 5298
            animal organ development 4055
              bone development 252
                bone cell development 38
                  megakaryocyte development 20
                  osteoclast development + 18
paths to the root