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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:bone cell development
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Accession:GO:0098751 term browser browse the term
Definition:The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Comment:Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.



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negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)
RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:29149593)
(MGI:6106664|PMID:29149593)
RGD PMID:29149593 MGI:6106664 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO
IEA
(PMID:7961821)
GO_REF:0000107
RGD
Ensembl
PMID:7961821 GO_REF:0000107 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO
IEA
ISS
(MGI:5575464|PMID:22467241)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
CAFA
PMID:22467241 GO_REF:0000024 GO_REF:0000107 MGI:5575464 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034
JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 acts_upstream_of_or_within ISO MGI:5568128|MGI:98397 (MGI:5564766|PMID:23526378) RGD PMID:23526378 MGI:5564766 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
JBrowse link
G Mir34a microRNA 34a acts_upstream_of_or_within_negative_effect ISO (MGI:5613071|PMID:25043055) RGD PMID:25043055 MGI:5613071 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IEP RGD PMID:7527035 RGD:632779 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2142227 (MGI:5564766|PMID:23526378)
RGD PMID:23526378 PMID:21873635 MGI:5564766, RGD:13792537 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5297759|PMID:21841309)
GO_REF:0000107
RGD
Ensembl
PMID:21841309 GO_REF:0000107 MGI:5297759 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
osteoclast maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO MGI:2656539|MGI:5428020 (MGI:5427766|PMID:22615579) RGD PMID:22615579 MGI:5427766 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6458683|PMID:30700695) RGD PMID:30700695 MGI:6458683 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Slc9b2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914) RGD PMID:18269914 MGI:3785147 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096)
GO_REF:0000107
RGD
Ensembl
PMID:18269914 PMID:22437732 PMID:23980096 GO_REF:0000107 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3653295|PMID:14969392) RGD PMID:14969392 MGI:3653295 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch2 notch receptor 2 involved_in ISO
IEA
ISS
(PMID:29149593)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:29149593 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1277211 (MGI:5467208|PMID:22451653)
RGD PMID:22451653 PMID:21873635 MGI:5467208, RGD:13792537 NCBI chr18:71,507,773...71,521,722
Ensembl chr18:71,505,399...71,521,881
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp acts_upstream_of_or_within ISO MGI:3646642 (MGI:5467208|PMID:22451653) RGD PMID:22451653 MGI:5467208 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    developmental process 6893
      cellular developmental process 4651
        cell development 3225
          bone cell development 20
            osteoclast development + 20
Path 2
Term Annotations click to browse term
  biological_process 19818
    developmental process 6893
      anatomical structure development 6417
        multicellular organism development 5169
          system development 4449
            skeletal system development 570
              bone development 258
                bone cell development 20
                  osteoclast development + 20
paths to the root