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ONTOLOGY REPORT - ANNOTATIONS


Term:fast, calcium ion-dependent exocytosis of neurotransmitter
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Accession:GO:0098746 term browser browse the term
Definition:The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
Synonyms:exact_synonym: synchronous, calcium ion-dependent exocytosis of neurotransmitter


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fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 involved_in ISO (MGI:3040539|PMID:12526776)
(MGI:3653150|PMID:9194562), (MGI:69538|PMID:7954835)
ParkinsonsUK-UCL PMID:7954835 PMID:9194562 PMID:12526776 MGI:3040539 MGI:3653150 MGI:69538 NCBI chrNW_004936698:65,210...575,538 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12300
    cellular process 11489
      cellular localization 2452
        establishment of localization in cell 1767
          synaptic vesicle exocytosis 131
            calcium ion-regulated exocytosis of neurotransmitter 17
              fast, calcium ion-dependent exocytosis of neurotransmitter 1
Path 2
Term Annotations click to browse term
  biological_process 12300
    localization 4949
      establishment of localization 3527
        transport 3366
          export from cell 871
            secretion by cell 828
              signal release 561
                signal release from synapse 172
                  neurotransmitter secretion 172
                    synaptic vesicle exocytosis 131
                      calcium ion-regulated exocytosis of neurotransmitter 17
                        fast, calcium ion-dependent exocytosis of neurotransmitter 1
paths to the root