Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:fast, calcium ion-dependent exocytosis of neurotransmitter
go back to main search page
Accession:GO:0098746 term browser browse the term
Definition:The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
Synonyms:exact_synonym: synchronous, calcium ion-dependent exocytosis of neurotransmitter



show annotations for term's descendants           Sort by:
 
fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin I involved_in IDA
IMP
(MGI:3040539|PMID:12526776)
(MGI:3653150|PMID:9194562), (MGI:69538|PMID:7954835)
ParkinsonsUK-UCL PMID:7954835 PMID:9194562 PMID:12526776 MGI:3040539 MGI:3653150 MGI:69538 NCBI chr10:108,497,650...109,010,980
Ensembl chr10:108,497,650...109,010,982
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28652
    cellular process 17706
      cellular localization 2989
        establishment of localization in cell 2233
          synaptic vesicle exocytosis 144
            calcium ion-regulated exocytosis of neurotransmitter 22
              fast, calcium ion-dependent exocytosis of neurotransmitter 1
Path 2
Term Annotations click to browse term
  biological_process 28652
    localization 6422
      establishment of localization 4813
        transport 4652
          export from cell 1028
            secretion by cell 974
              signal release 616
                signal release from synapse 192
                  neurotransmitter secretion 192
                    synaptic vesicle exocytosis 144
                      calcium ion-regulated exocytosis of neurotransmitter 22
                        fast, calcium ion-dependent exocytosis of neurotransmitter 1
paths to the root