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ONTOLOGY REPORT - ANNOTATIONS


Term:skeletal muscle fiber differentiation
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Accession:GO:0098528 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.


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skeletal muscle fiber differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within
ISO (MGI:5700633|PMID:25940086)
(MGI:5565628|PMID:24361185)
RGD PMID:24361185 PMID:25940086 MGI:5565628 MGI:5700633 NCBI chr 8:130,416,265...130,421,871
Ensembl chr 8:130,416,355...130,421,871
JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5298278|PMID:21884692) RGD PMID:21884692 MGI:5298278 NCBI chr 6:95,984,868...95,999,709
Ensembl chr 6:95,984,868...95,998,529
JBrowse link
positive regulation of skeletal muscle fiber differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbm24 RNA binding motif protein 24 involved_in ISO (MGI:6148527|PMID:25313962) RGD PMID:25313962 MGI:6148527 NCBI chr17:18,671,037...18,682,876
Ensembl chr17:18,671,044...18,682,876
JBrowse link
positive regulation of tongue muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in ISO (MGI:3809313|PMID:18816858) RGD PMID:18816858 MGI:3809313 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Tbx1 T-box transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3809313|PMID:18816858)
UniProt
RGD
PMID:18816858 GO_REF:0000024 MGI:3809313 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
regulation of skeletal muscle fiber differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nln neurolysin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4125183 (MGI:5588076|PMID:24719333)
Ensembl
RGD
PMID:24719333 GO_REF:0000107 MGI:5588076 NCBI chr 2:34,086,970...34,185,835
Ensembl chr 2:34,087,880...34,185,812
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      cellular developmental process 4460
        cell differentiation 4364
          skeletal muscle cell differentiation 79
            skeletal muscle fiber differentiation 6
              negative regulation of skeletal muscle fiber differentiation + 0
              positive regulation of skeletal muscle fiber differentiation + 3
              regulation of skeletal muscle fiber differentiation + 4
              tongue muscle cell differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure development 6178
        multicellular organism development 5617
          system development 5288
            animal organ development 4053
              muscle organ development 352
                skeletal muscle organ development 221
                  skeletal muscle tissue development 206
                    skeletal muscle cell differentiation 79
                      skeletal muscle fiber differentiation 6
                        negative regulation of skeletal muscle fiber differentiation + 0
                        positive regulation of skeletal muscle fiber differentiation + 3
                        regulation of skeletal muscle fiber differentiation + 4
                        tongue muscle cell differentiation + 2
paths to the root