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ONTOLOGY REPORT - ANNOTATIONS

Term:lamellipodium organization
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Accession:GO:0097581 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.


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lamellipodium organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc5 actin related protein 2/3 complex, subunit 5 IMP RGD PMID:21281821 RGD:11049483 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410 		JBrowse link
G Cttn cortactin involved_in IMP PMID:18768925 UniProt PMID:18768925 RGD:10047281 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 acts_upstream_of_or_within ISO (MGI:3810204|PMID:18413296) RGD PMID:18413296 MGI:3810204 NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507 		JBrowse link
lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007032.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ablim1 actin-binding LIM protein 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:22684256)
PMID:21873635		 RGD PMID:22684256 PMID:21873635 RGD:13792537 NCBI chr 1:256,084,293...256,372,075
Ensembl chr 1:256,084,297...256,371,969 		JBrowse link
G Ablim2 actin binding LIM protein family, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:74,865,409...74,990,334
Ensembl chr14:74,866,281...74,990,334 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:22684256)		 RGD PMID:22684256 PMID:21873635 RGD:13792537 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380 		JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO MGI:3578221 (MGI:3577694|PMID:15728191) RGD PMID:15728191 MGI:3577694 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 involved_in ISO (PMID:17599059) RGD PMID:17599059 NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:5447607|PMID:18325335)		 UniProt
RGD		 PMID:18325335 PMID:21873635 GO_REF:0000024 MGI:5447607, RGD:13792537 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:5447607|PMID:18325335)		 UniProt
RGD		 PMID:18325335 PMID:21873635 GO_REF:0000024 MGI:5447607, RGD:13792537 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (MGI:4397629|PMID:19806181)
(MGI:3051184|PMID:15294161)		 RGD PMID:15294161 PMID:19806181 MGI:3051184 MGI:4397629 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:19846667) RGD PMID:19846667 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326 		JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (PMID:16139227) RGD PMID:16139227 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Cdh13 cadherin 13 involved_in ISO (PMID:15703273) RGD PMID:15703273 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3033285|PMID:14765121)		 RGD PMID:14765121 PMID:21873635 MGI:3033285, RGD:13792537 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Dmtn dematin actin binding protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2179874|PMID:11527409)		 Ensembl
RGD		 PMID:11527409 GO_REF:0000107 MGI:2179874 NCBI chr11:84,399,885...84,551,013
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Golph3 golgi phosphoprotein 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23500462)		 UniProt
Ensembl
RGD		 PMID:23500462 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in IMP PMID:20091784 ARUK-UCL PMID:20091784 RGD:6480646 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:5430902|PMID:10982396) RGD PMID:10982396 MGI:5430902 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nck1 NCK adaptor protein 1 acts_upstream_of_or_within ISO MGI:2667151 (MGI:2664446|PMID:12808099) RGD PMID:12808099 MGI:2664446 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 acts_upstream_of_or_within ISO MGI:2667153 (MGI:2664446|PMID:12808099) RGD PMID:12808099 MGI:2664446 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Nckap1 NCK-associated protein 1 acts_upstream_of_or_within ISO MGI:3578145 (MGI:3033285|PMID:14765121), (MGI:3701029|PMID:16831833) RGD PMID:14765121 PMID:16831833 MGI:3033285 MGI:3701029 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nup85 nucleoporin 85 acts_upstream_of_or_within ISO (MGI:3588593|PMID:15995708) RGD PMID:15995708 MGI:3588593 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:20091784 ARUK-UCL PMID:20091784 RGD:6480646 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Parvb parvin, beta involved_in ISO
IBA		 (PMID:18325335)
PMID:21873635		 RGD PMID:18325335 PMID:21873635 RGD:13792537 NCBI chr 7:115,360,254...115,445,767
Ensembl chr 7:115,360,261...115,445,766 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:3614822 (MGI:5616959|PMID:25429154) RGD PMID:25429154 MGI:5616959 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O involved_in ISS
ISO		 GO_REF:0000024
(MGI:4941445|PMID:20398064)		 UniProt
RGD		 PMID:20398064 GO_REF:0000024 MGI:4941445 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771 		JBrowse link
G Pxn paxillin acts_upstream_of_or_within ISO (MGI:2680875|PMID:14636584) RGD PMID:14636584 MGI:2680875 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:9312003)
GO_REF:0000107
(MGI:3577694|PMID:15728191)		 RGD
Ensembl		 PMID:9312003 PMID:15728191 GO_REF:0000107 MGI:3577694 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rhod ras homolog family member D involved_in ISO (PMID:23087206) RGD PMID:23087206 NCBI chr 1:201,708,699...201,724,405
Ensembl chr 1:201,708,699...201,722,632 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3703727|PMID:11726541)		 UniProt
RGD		 PMID:11726541 GO_REF:0000024 MGI:3703727 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2176658|PMID:11786545)
GO_REF:0000107		 RGD
Ensembl		 PMID:11786545 GO_REF:0000107 MGI:2176658 NCBI chr 1:181,048,622...181,057,036
Ensembl chr 1:181,048,623...181,056,579 		JBrowse link
G Spata13 spermatogenesis associated 13 involved_in ISO
IBA		 (PMID:17599059)
PMID:21873635		 RGD PMID:17599059 PMID:21873635 RGD:13792537 NCBI chr15:34,778,479...34,907,645
Ensembl chr15:34,778,473...34,905,114 		JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (PMID:31473225) RGD PMID:31473225 NCBI chr 3:118,390,659...118,396,842
Ensembl chr 3:118,390,575...118,394,531 		JBrowse link
G Vav2 vav guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO MGI:1888518 (MGI:3587490|PMID:15728722) RGD PMID:15728722 MGI:3587490 NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 acts_upstream_of_or_within ISO MGI:102718 (MGI:3587490|PMID:15728722) RGD PMID:15728722 MGI:3587490 NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321 		JBrowse link
G Vcl vinculin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2447097|PMID:12473693)		 Ensembl
RGD		 PMID:12473693 GO_REF:0000107 MGI:2447097 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Wasf2 WASP family member 2 acts_upstream_of_or_within ISO MGI:2670134 (MGI:2668788|PMID:12879075) RGD PMID:12879075 MGI:2668788 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
G Wasf3 WASP family member 3 acts_upstream_of_or_within ISO (MGI:3625634|PMID:16723544) RGD PMID:16723544 MGI:3625634 NCBI chr12:8,563,805...8,660,799
Ensembl chr12:8,562,062...8,660,751 		JBrowse link
G Whamm WASP homolog associated with actin, golgi membranes and microtubules involved_in ISO (PMID:23087206) RGD PMID:23087206 NCBI chr 1:135,526,363...135,557,091
Ensembl chr 1:135,526,386...135,554,759 		JBrowse link
lamellipodium assembly involved in ameboidal cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 involved_in ISO (PMID:20810653) RGD PMID:20810653 NCBI chr13:42,745,956...42,967,083
Ensembl chr13:42,745,947...42,967,058 		JBrowse link
lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3847627|PMID:17664349)		 Ensembl
RGD		 PMID:17664349 GO_REF:0000107 MGI:3847627 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Myo9b myosin IXb acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:4867915 (MGI:4818714|PMID:20566876)
PMID:21873635		 RGD PMID:20566876 PMID:21873635 MGI:4818714, RGD:13792537 NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126 		JBrowse link
G Plekho1 pleckstrin homology domain containing O1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5494518|PMID:22553210)		 Ensembl
RGD		 PMID:22553210 GO_REF:0000107 MGI:5494518 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785 		JBrowse link
G Snx1 sorting nexin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20604901)		 UniProt
RGD		 PMID:20604901 GO_REF:0000024 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360 		JBrowse link
G Snx2 sorting nexin 2 involved_in ISO (PMID:20604901) RGD PMID:20604901 NCBI chr18:46,602,223...46,643,870
Ensembl chr18:46,602,284...46,643,865 		JBrowse link
G Wasf1 WASP family member 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:29961568)
(MGI:3847627|PMID:17664349)
GO_REF:0000024		 RGD
UniProt		 PMID:17664349 PMID:29961568 GO_REF:0000024 MGI:3847627 NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996 		JBrowse link
G Wasf2 WASP family member 2 acts_upstream_of_or_within ISO (MGI:3847627|PMID:17664349) RGD PMID:17664349 MGI:3847627 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in ISO (MGI:6508508|PMID:26428302) RGD PMID:26428302 MGI:6508508 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
ISS		 (PMID:16489009)
GO_REF:0000024		 RGD
UniProt		 PMID:16489009 GO_REF:0000024 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Mir196a microRNA 196a involved_in ISO (PMID:22773844) RGD PMID:22773844 NCBI chr 7:134,110,400...134,110,509
Ensembl chr 7:134,110,400...134,110,509 		JBrowse link
G Mir196c microRNA 196c involved_in ISO (PMID:22773844) RGD PMID:22773844 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085 		JBrowse link
G Plxnb3 plexin B3 involved_in IMP PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:151,493,832...151,508,688
Ensembl chr  X:151,494,207...151,508,674 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (PMID:16439689) RGD PMID:16439689 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
negative regulation of lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin-related protein 2/3 complex inhibitor involved_in ISO (PMID:24132237) RGD PMID:24132237 NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124 		JBrowse link
G Coro1b coronin 1B involved_in IMP PMID:22619279 UniProt PMID:22619279 RGD:10047170 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:19171758) RGD PMID:19171758 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Actr2 actin related protein 2 involved_in ISO (PMID:29058690) RGD PMID:29058690 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Actr3 actin related protein 3 involved_in IMP
ISO
ISS		 (PMID:29058690)
GO_REF:0000024		 RGD
UniProt		 PMID:29058690 PMID:18256280 GO_REF:0000024, RGD:2306202 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Akirin1 akirin 1 involved_in IBA
ISO		 PMID:21873635
(MGI:3850794|PMID:19406121)		 RGD PMID:19406121 PMID:21873635 MGI:3850794, RGD:13792537 NCBI chr 5:135,989,378...136,004,782
Ensembl chr 5:135,989,465...136,004,762 		JBrowse link
G Aqp1 aquaporin 1 IMP RGD PMID:19539607 RGD:2316079 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:18560548)		 Ensembl
RGD		 PMID:18560548 PMID:15252126 GO_REF:0000107, RGD:2306210 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Atp7a ATPase copper transporting alpha IMP RGD PMID:20671235 RGD:11341707 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 involved_in ISO (MGI:5908783|PMID:25533347) RGD PMID:25533347 MGI:5908783 NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416 		JBrowse link
G Avil advillin involved_in ISO
ISS		 (PMID:29058690)
GO_REF:0000024		 RGD
UniProt		 PMID:29058690 GO_REF:0000024 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548 PMID:21107423 NCBI chr 4:146,750,821...146,766,050
Ensembl chr 4:146,750,821...146,768,856 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO (PMID:8625410) RGD PMID:8625410 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Clrn1 clarin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19423712)
GO_REF:0000107		 RGD
Ensembl		 PMID:19423712 GO_REF:0000107 NCBI chr 2:143,084,030...143,130,948
Ensembl chr 2:143,084,030...143,130,948 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14617821 RGD:9685179 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within ISO (MGI:5546532|PMID:23967341) RGD PMID:23967341 MGI:5546532 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9571235)		 UniProt
RGD		 PMID:9571235 GO_REF:0000024 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IMP RGD PMID:15302889 RGD:2316937 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Mstn myostatin involved_in ISS
ISO		 GO_REF:0000024
(MGI:3850794|PMID:19406121)		 UniProt
RGD		 PMID:19406121 GO_REF:0000024 MGI:3850794 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) RGD PMID:15467718 MGI:3510095 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO (PMID:18560548), (PMID:21107423)
(MGI:5897521|PMID:27927633)		 RGD PMID:18560548 PMID:21107423 PMID:27927633 MGI:5897521 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Ocln occludin involved_in ISO (PMID:20152177) RGD PMID:20152177 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6450670|PMID:11038173)		 Ensembl
RGD		 PMID:11038173 GO_REF:0000107 MGI:6450670 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29058690)		 UniProt
Ensembl
RGD		 PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within		 IMP
IEA
ISO		 GO_REF:0000107
(PMID:15467718)
(PMID:19625648), (PMID:8625410)		 Ensembl
RGD		 PMID:8625410 PMID:15467718 PMID:19625648 PMID:12105187 GO_REF:0000107, RGD:1299247 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (PMID:19625648)
(MGI:4355276|PMID:19625648)		 RGD PMID:19625648 MGI:4355276 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in ISO (PMID:17910947) RGD PMID:17910947 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Wasf2 WASP family member 2 involved_in ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548 PMID:21107423 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:19756656) RGD PMID:19756656 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
positive regulation of lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in ISO (PMID:21423176) UniProt PMID:21423176 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Coro1b coronin 1B involved_in ISO
IEA		 (PMID:17350576)
GO_REF:0000107		 RGD
Ensembl		 PMID:17350576 GO_REF:0000107 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Coro1c coronin 1C involved_in ISO (PMID:19913511) RGD PMID:19913511 NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in ISO UniProtKB:P09327 (PMID:18054784) RGD PMID:18054784 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Gng2 G protein subunit gamma 2 involved_in ISO (PMID:18054784) RGD PMID:18054784 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183 		JBrowse link
G Rreb1 ras responsive element binding protein 1 involved_in ISO (PMID:18394891) RGD PMID:18394891 NCBI chr17:26,876,686...27,002,615
Ensembl chr17:26,876,697...27,002,615 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:18054784) RGD PMID:18054784 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Vil1 villin 1 involved_in ISO UniProtKB:Q13822 (PMID:18054784) RGD PMID:18054784 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
positive regulation of lamellipodium organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028)
(MGI:3588909|PMID:16054028)		 RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26578515) RGD PMID:26578515 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin3 bridging integrator 3 acts_upstream_of_or_within ISO MGI:3512131 (MGI:5517720|PMID:23872330) RGD PMID:23872330 MGI:5517720 NCBI chr15:45,173,725...45,212,607
Ensembl chr15:45,173,732...45,212,604 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (PMID:10565303) RGD PMID:10565303 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:19573808) RGD PMID:19573808 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Fer FER tyrosine kinase involved_in ISO
ISS		 (PMID:19738202)
GO_REF:0000024		 RGD
UniProt		 PMID:19738202 GO_REF:0000024 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO UniProtKB:P60953|UniProtKB:P63000 (PMID:8625410) RGD PMID:8625410 NCBI chr  X:14,405,096...14,413,850
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
regulation of lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO
ISS		 (PMID:20962267)
GO_REF:0000024		 RGD
UniProt		 PMID:20962267 GO_REF:0000024 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Pdpn podoplanin involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:20962267)		 UniProt
RGD		 PMID:20962267 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Vil1 villin 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5009178|PMID:12937273)		 RGD PMID:12937273 PMID:21873635 MGI:5009178, RGD:13792537 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          cell projection organization 1771
            plasma membrane bounded cell projection organization 1735
              lamellipodium organization 99
                lamellipodium assembly + 79
                lamellipodium morphogenesis + 19
                negative regulation of lamellipodium organization + 11
                positive regulation of lamellipodium organization + 40
                regulation of lamellipodium organization + 58
paths to the root