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ONTOLOGY REPORT - ANNOTATIONS

Term:lamellipodium organization
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Accession:GO:0097581 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.

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lamellipodium organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc5 actin related protein 2/3 complex, subunit 5 IMP RGD PMID:21281821 RGD:11049483 NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879 		JBrowse link
G Cttn cortactin involved_in IMP PMID:18768925 UniProt PMID:18768925 RGD:10047281 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152 		JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 acts_upstream_of_or_within ISO (MGI:3810204|PMID:18413296) RGD PMID:18413296 MGI:3810204 NCBI chr19:40,904,779...40,925,660
Ensembl chr19:40,905,847...40,925,660 		JBrowse link
lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007032.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:277,853,875...278,042,312 JBrowse link
G Ablim2 actin binding LIM protein family, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:80,044,217...80,169,491
Ensembl chr14:80,045,078...80,169,472 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:57,126,534...57,245,965
Ensembl chr18:57,128,399...57,245,666 		JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO MGI:3578221 (MGI:3577694|PMID:15728191) RGD PMID:15728191 MGI:3577694 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456 		JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 involved_in ISO (PMID:17599059) RGD PMID:17599059 NCBI chr 9:41,160,562...41,305,015
Ensembl chr 9:41,295,909...41,302,501 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5447607|PMID:18325335)		 UniProt
RGD		 PMID:18325335 GO_REF:0000024 MGI:5447607 NCBI chr  X:159,722,031...159,841,344
Ensembl chr  X:159,723,866...159,841,072 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5447607|PMID:18325335)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18325335 GO_REF:0000024 GO_REF:0000107 MGI:5447607 NCBI chr16:83,006,732...83,117,065
Ensembl chr16:83,006,718...83,132,785 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3051184|PMID:15294161)
(MGI:4397629|PMID:19806181)		 Ensembl
RGD		 PMID:15294161 PMID:19806181 GO_REF:0000107 MGI:3051184 MGI:4397629 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:19846667) RGD PMID:19846667 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403 		JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (PMID:16139227) RGD PMID:16139227 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263 		JBrowse link
G Cdh13 cadherin 13 involved_in ISO (PMID:15703273) RGD PMID:15703273 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3033285|PMID:14765121)		 RGD PMID:14765121, PMID:21873635 MGI:3033285, RGD:13792537 NCBI chr 1:114,258,773...114,347,138
Ensembl chr 1:114,258,719...114,347,137 		JBrowse link
G Dmtn dematin actin binding protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:52,292,762...52,320,385
Ensembl chr15:52,292,765...52,320,385 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2179874|PMID:11527409)		 Ensembl
RGD		 PMID:11527409 GO_REF:0000107 MGI:2179874 NCBI chr11:88,699,222...88,796,677
Ensembl chr11:88,699,222...88,796,677 		JBrowse link
G Golph3 golgi phosphoprotein 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23500462)		 UniProt
Ensembl
RGD		 PMID:23500462 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:62,360,754...62,388,773
Ensembl chr 2:62,360,754...62,388,771 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in IMP PMID:20091784 ARUK-UCL PMID:20091784 RGD:6480646 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:5430902|PMID:10982396) RGD PMID:10982396 MGI:5430902 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Nck1 NCK adaptor protein 1 acts_upstream_of_or_within ISO MGI:2667151 (MGI:2664446|PMID:12808099) RGD PMID:12808099 MGI:2664446 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779 		JBrowse link
G Nck2 NCK adaptor protein 2 acts_upstream_of_or_within ISO MGI:2667153 (MGI:2664446|PMID:12808099) RGD PMID:12808099 MGI:2664446 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284 		JBrowse link
G Nckap1 NCK-associated protein 1 acts_upstream_of_or_within ISO MGI:3578145 (MGI:3033285|PMID:14765121), (MGI:3701029|PMID:16831833) RGD PMID:14765121 PMID:16831833 MGI:3033285 MGI:3701029 NCBI chr 3:67,725,180...67,804,680
Ensembl chr 3:67,725,947...67,787,990 		JBrowse link
G Nup85 nucleoporin 85 acts_upstream_of_or_within ISO (MGI:3588593|PMID:15995708) RGD PMID:15995708 MGI:3588593 NCBI chr10:104,118,999...104,137,258
Ensembl chr10:104,118,945...104,137,319 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:20091784 ARUK-UCL PMID:20091784 RGD:6480646 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548 		JBrowse link
G Parvb parvin, beta involved_in ISO
IBA		 (PMID:18325335)
PMID:21873635		 RGD PMID:18325335, PMID:21873635 RGD:13792537 NCBI chr 7:125,189,827...125,275,977
Ensembl chr 7:125,189,827...125,277,689 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:3614822 (MGI:5616959|PMID:25429154) RGD PMID:25429154 MGI:5616959 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O involved_in ISS
ISO		 GO_REF:0000024
(MGI:4941445|PMID:20398064)		 UniProt
RGD		 PMID:20398064 GO_REF:0000024 MGI:4941445 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677 		JBrowse link
G Pxn paxillin acts_upstream_of_or_within ISO (MGI:2680875|PMID:14636584) RGD PMID:14636584 MGI:2680875 NCBI chr12:46,797,953...46,845,107
Ensembl chr12:46,797,954...46,845,080 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:9312003)
(MGI:3577694|PMID:15728191)		 RGD PMID:9312003 PMID:15728191 MGI:3577694 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873 		JBrowse link
G Rhod ras homolog family member D involved_in ISO (PMID:23087206) RGD PMID:23087206 NCBI chr 1:219,668,352...219,682,287
Ensembl chr 1:219,668,352...219,682,287 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3703727|PMID:11726541)		 UniProt
RGD		 PMID:11726541 GO_REF:0000024 MGI:3703727 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 acts_upstream_of_or_within ISO (MGI:2176658|PMID:11786545) RGD PMID:11786545 MGI:2176658 NCBI chr 1:197,878,839...197,888,223
Ensembl chr 1:197,878,840...197,886,759 		JBrowse link
G Spata13 spermatogenesis associated 13 involved_in ISO (PMID:17599059) RGD PMID:17599059 NCBI chr15:40,937,652...41,066,645
Ensembl chr15:40,937,708...41,066,769 		JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (PMID:31473225) RGD PMID:31473225 NCBI chr 3:123,712,907...123,720,787
Ensembl chr 3:123,714,564...123,718,432 		JBrowse link
G Vav2 vav guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO MGI:1888518 (MGI:3587490|PMID:15728722) RGD PMID:15728722 MGI:3587490 NCBI chr 3:5,811,504...5,976,311
Ensembl chr 3:5,811,504...5,976,244 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 acts_upstream_of_or_within ISO MGI:102718 (MGI:3587490|PMID:15728722) RGD PMID:15728722 MGI:3587490 NCBI chr 2:212,247,061...212,585,818
Ensembl chr 2:212,247,451...212,585,818 		JBrowse link
G Vcl vinculin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2447097|PMID:12473693)		 Ensembl
RGD		 PMID:12473693 GO_REF:0000107 MGI:2447097 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702 		JBrowse link
G Wasf2 WASP family member 2 acts_upstream_of_or_within ISO MGI:2670134 (MGI:2668788|PMID:12879075) RGD PMID:12879075 MGI:2668788 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238 		JBrowse link
G Wasf3 WASP family member 3 acts_upstream_of_or_within ISO (MGI:3625634|PMID:16723544) RGD PMID:16723544 MGI:3625634 NCBI chr12:10,297,896...10,391,014
Ensembl chr12:10,298,555...10,391,270 		JBrowse link
G Whamm WASP homolog associated with actin, golgi membranes and microtubules involved_in ISO (PMID:23087206) RGD PMID:23087206 NCBI chr 1:143,401,986...143,430,356
Ensembl chr 1:143,401,986...143,430,356 		JBrowse link
lamellipodium assembly involved in ameboidal cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 involved_in ISO (PMID:20810653) RGD PMID:20810653 NCBI chr13:48,065,280...48,286,888
Ensembl chr13:48,068,158...48,286,720 		JBrowse link
lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3847627|PMID:17664349)		 Ensembl
RGD		 PMID:17664349 GO_REF:0000107 MGI:3847627 NCBI chr17:89,951,662...90,033,334
Ensembl chr17:89,951,752...90,033,328 		JBrowse link
G Myo9b myosin IXb acts_upstream_of_or_within ISO MGI:4867915 (MGI:4818714|PMID:20566876) RGD PMID:20566876 MGI:4818714 NCBI chr16:19,669,373...19,754,065
Ensembl chr16:19,669,411...19,754,069 		JBrowse link
G Plekho1 pleckstrin homology domain containing O1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5494518|PMID:22553210)		 Ensembl
RGD		 PMID:22553210 GO_REF:0000107 MGI:5494518 NCBI chr 2:198,112,104...198,120,202
Ensembl chr 2:198,112,076...198,120,120 		JBrowse link
G Snx1 sorting nexin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20604901)		 UniProt
RGD		 PMID:20604901 GO_REF:0000024 NCBI chr 8:71,745,687...71,786,182
Ensembl chr 8:71,745,896...71,784,551 		JBrowse link
G Snx2 sorting nexin 2 involved_in ISO (PMID:20604901) RGD PMID:20604901 NCBI chr18:48,132,386...48,173,974
Ensembl chr18:48,132,414...48,173,971 		JBrowse link
G Wasf1 WASP family member 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:29961568)
(MGI:3847627|PMID:17664349)
GO_REF:0000024		 RGD
UniProt		 PMID:17664349 PMID:29961568 GO_REF:0000024 MGI:3847627 NCBI chr20:48,456,191...48,503,768
Ensembl chr20:48,455,705...48,503,898 		JBrowse link
G Wasf2 WASP family member 2 acts_upstream_of_or_within ISO (MGI:3847627|PMID:17664349) RGD PMID:17664349 MGI:3847627 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238 		JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6508508|PMID:26428302)		 Ensembl
RGD		 PMID:26428302 GO_REF:0000107 MGI:6508508 NCBI chr10:83,644,086...83,655,182
Ensembl chr10:83,644,086...83,655,182 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
ISS
IEA		 (PMID:16489009)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:16489009 GO_REF:0000024 GO_REF:0000107 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952 		JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plxnb3 plexin B3 involved_in IMP PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:157,015,297...157,030,147
Ensembl chr  X:157,015,305...157,028,434 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:16439689)
GO_REF:0000107		 RGD
Ensembl		 PMID:16439689 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361 		JBrowse link
negative regulation of lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin-related protein 2/3 complex inhibitor involved_in ISO (PMID:24132237) RGD PMID:24132237 NCBI chr 1:141,664,790...141,672,789
Ensembl chr 1:141,662,850...141,672,810 		JBrowse link
G Coro1b coronin 1B involved_in IMP PMID:22619279 UniProt PMID:22619279 RGD:10047170 NCBI chr 1:219,397,827...219,403,253
Ensembl chr 1:219,397,850...219,403,260 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:19171758) RGD PMID:19171758 NCBI chr 1:243,201,073...243,398,531
Ensembl chr 1:243,276,403...243,398,536 		JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600 		JBrowse link
G Actr2 actin related protein 2 involved_in ISO (PMID:29058690) RGD PMID:29058690 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649 		JBrowse link
G Actr3 actin related protein 3 involved_in IMP
IEA
ISO
ISS		 GO_REF:0000107
(PMID:29058690)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:29058690, PMID:18256280 GO_REF:0000024 GO_REF:0000107, RGD:2306202 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658 		JBrowse link
G Akirin1 akirin 1 involved_in IBA
ISO		 PMID:21873635
(MGI:3850794|PMID:19406121)		 RGD PMID:19406121, PMID:21873635 MGI:3850794, RGD:13792537 NCBI chr 5:141,415,226...141,430,627
Ensembl chr 5:141,415,075...141,430,659 		JBrowse link
G Aqp1 aquaporin 1 IMP RGD PMID:19539607 RGD:2316079 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:18560548)		 Ensembl
RGD		 PMID:18560548, PMID:15252126 GO_REF:0000107, RGD:2306210 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871 		JBrowse link
G Atp7a ATPase copper transporting alpha IMP RGD PMID:20671235 RGD:11341707 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644 		JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 involved_in ISO (MGI:5908783|PMID:25533347) RGD PMID:25533347 MGI:5908783 NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816 		JBrowse link
G Avil advillin involved_in ISO
ISS		 (PMID:29058690)
GO_REF:0000024		 RGD
UniProt		 PMID:29058690 GO_REF:0000024 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588 		JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548 PMID:21107423 NCBI chr 4:145,559,206...145,574,438
Ensembl chr 4:145,559,206...145,574,438 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO (PMID:8625410) RGD PMID:8625410 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337 		JBrowse link
G Clrn1 clarin 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:149,049,925...149,088,787
Ensembl chr 2:149,049,925...149,088,787 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 1:114,258,773...114,347,138
Ensembl chr 1:114,258,719...114,347,137 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14617821 RGD:9685179 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524 		JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within ISO (MGI:5546532|PMID:23967341) RGD PMID:23967341 MGI:5546532 NCBI chr  X:138,095,707...138,149,702
Ensembl chr  X:138,098,185...138,148,967 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:9571235)		 UniProt
Ensembl
RGD		 PMID:9571235 GO_REF:0000024 GO_REF:0000107 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IMP RGD PMID:15302889 RGD:2316937 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775 		JBrowse link
G Mstn myostatin involved_in ISS
ISO		 GO_REF:0000024
(MGI:3850794|PMID:19406121)		 UniProt
RGD		 PMID:19406121 GO_REF:0000024 MGI:3850794 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) RGD PMID:15467718 MGI:3510095 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Nckap1 NCK-associated protein 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5897521|PMID:27927633)
(PMID:18560548), (PMID:21107423)		 Ensembl
RGD		 PMID:18560548 PMID:21107423 PMID:27927633 GO_REF:0000107 MGI:5897521 NCBI chr 3:67,725,180...67,804,680
Ensembl chr 3:67,725,947...67,787,990 		JBrowse link
G Ocln occludin involved_in ISO (PMID:20152177) RGD PMID:20152177 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6450670|PMID:11038173)		 Ensembl
RGD		 PMID:11038173 GO_REF:0000107 MGI:6450670 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867 		JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29058690)		 UniProt
Ensembl
RGD		 PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IMP
ISO		 (PMID:19625648), (PMID:8625410) RGD PMID:8625410 PMID:19625648, PMID:12105187 RGD:1299247 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (PMID:19625648)
(MGI:4355276|PMID:19625648)		 RGD PMID:19625648 MGI:4355276 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in ISO (PMID:17910947) RGD PMID:17910947 NCBI chr 8:114,897,011...114,909,531
Ensembl chr 8:114,897,011...114,909,531 		JBrowse link
G Wasf2 WASP family member 2 involved_in ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548 PMID:21107423 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:19756656) RGD PMID:19756656 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046 		JBrowse link
positive regulation of lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in ISO (PMID:21423176) UniProt PMID:21423176 NCBI chr16:83,006,732...83,117,065
Ensembl chr16:83,006,718...83,132,785 		JBrowse link
G Coro1b coronin 1B involved_in ISO
IEA		 (PMID:17350576)
GO_REF:0000107		 RGD
Ensembl		 PMID:17350576 GO_REF:0000107 NCBI chr 1:219,397,827...219,403,253
Ensembl chr 1:219,397,850...219,403,260 		JBrowse link
G Coro1c coronin 1C involved_in ISO (PMID:19913511) RGD PMID:19913511 NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P09327 (PMID:18054784)		 Ensembl
RGD		 PMID:18054784 GO_REF:0000107 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001 		JBrowse link
G Gng2 G protein subunit gamma 2 involved_in ISO (PMID:18054784) RGD PMID:18054784 NCBI chr15:4,748,242...4,853,555
Ensembl chr15:4,850,122...4,853,555 		JBrowse link
G Rreb1 ras responsive element binding protein 1 involved_in ISO (PMID:18394891) RGD PMID:18394891 NCBI chr17:27,539,137...27,718,878
Ensembl chr17:27,539,133...27,665,266 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:18054784) RGD PMID:18054784 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Vil1 villin 1 involved_in ISO UniProtKB:Q13822 (PMID:18054784) RGD PMID:18054784 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621 		JBrowse link
positive regulation of lamellipodium organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028)
(MGI:3588909|PMID:16054028)		 RGD PMID:16054028 MGI:3588909 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26578515) RGD PMID:26578515 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019 		JBrowse link
regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin3 bridging integrator 3 acts_upstream_of_or_within ISO MGI:3512131 (MGI:5517720|PMID:23872330) RGD PMID:23872330 MGI:5517720 NCBI chr15:51,799,339...51,818,697
Ensembl chr15:51,779,839...51,818,699 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300 		JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (PMID:10565303) RGD PMID:10565303 NCBI chr15:52,292,762...52,320,385
Ensembl chr15:52,292,765...52,320,385 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:19573808) RGD PMID:19573808 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206 		JBrowse link
G Fer FER tyrosine kinase involved_in ISO
IEA
ISS		 (PMID:19738202)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19738202 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:111,557,804...111,868,583
Ensembl chr 9:111,597,037...111,862,670 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO UniProtKB:P42768 (PMID:8625410) RGD PMID:8625410 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:135,838,647...135,850,542
Ensembl chr 7:135,838,648...135,850,542 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:114,897,011...114,909,531
Ensembl chr 8:114,897,011...114,909,531 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO UniProtKB:P60953|UniProtKB:P63000 (PMID:8625410) RGD PMID:8625410 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105 		JBrowse link
regulation of lamellipodium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO
IEA
ISS		 (PMID:20962267)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20962267 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Pdpn podoplanin involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:20962267)		 UniProt
RGD		 PMID:20962267, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441 		JBrowse link
G Vil1 villin 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5009178|PMID:12937273)		 RGD PMID:12937273, PMID:21873635 MGI:5009178, RGD:13792537 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    cellular process 18484
      cellular component organization or biogenesis 6708
        cellular component organization 6463
          cell projection organization 1726
            plasma membrane bounded cell projection organization 1686
              lamellipodium organization 96
                lamellipodium assembly + 76
                lamellipodium morphogenesis + 19
                negative regulation of lamellipodium organization + 9
                positive regulation of lamellipodium organization + 40
                regulation of lamellipodium organization + 56
paths to the root