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ONTOLOGY REPORT - ANNOTATIONS

Term:programmed cell death in response to reactive oxygen species
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Accession:GO:0097468 term browser browse the term
Definition:Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
Synonyms:exact_synonym: PCD in response to reactive oxygen species;   reactive oxygen species-mediated PCD;   reactive oxygen species-mediated programmed cell death
 broad_synonym: PCD in response to oxidative stress;   programmed cell death in response to oxidative stress

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programmed cell death in response to reactive oxygen species term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pjvk pejvakin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:7,670,557...7,677,480
Ensembl chrNW_004936509:7,670,325...7,677,581 		JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k4 mitogen-activated protein kinase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:22652780) UniProt PMID:22652780 NCBI chrNW_004936593:4,650,624...4,693,387
Ensembl chrNW_004936593:4,651,114...4,692,534 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:420,591...426,890
Ensembl chrNW_004936745:420,073...426,393 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478
Ensembl chrNW_004936474:6,573,623...6,589,478 		JBrowse link
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:32412792 RGD:150429761 NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139 		JBrowse link
G Glrx glutaredoxin ISO RGD PMID:19938943 RGD:9686063 NCBI chrNW_004936523:7,535,650...7,544,339
Ensembl chrNW_004936523:7,535,857...7,541,864 		JBrowse link
G Hgf hepatocyte growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779 		JBrowse link
G Hk3 hexokinase 3 involved_in ISO PMID:21072205 CACAO PMID:21072205 RGD:10047370 NCBI chrNW_004936597:1,122,648...1,143,342
Ensembl chrNW_004936597:1,122,648...1,138,396 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478
Ensembl chrNW_004936474:6,573,623...6,589,478 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936826:748,256...753,460
Ensembl chrNW_004936826:747,291...753,442 		JBrowse link
G Trap1 TNF receptor associated protein 1 involved_in ISO PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chrNW_004936694:667,687...704,994
Ensembl chrNW_004936694:667,691...704,994 		JBrowse link
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G ISO RGD PMID:20594982 RGD:9685387 NCBI chrNW_004936487:16,282,115...16,285,486
Ensembl chrNW_004936487:16,282,398...16,285,418 		JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:23585551 RGD:7327146 NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138 		JBrowse link
G Foxa1 forkhead box A1 ISO RGD PMID:19649697 RGD:151665511 NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224 		JBrowse link
G Foxo3 forkhead box O3 ISO RGD PMID:23585551 RGD:7327146 NCBI chrNW_004936564:4,788,036...4,907,600
Ensembl chrNW_004936564:4,787,992...4,903,837 		JBrowse link
G Foxp1 forkhead box P1 ISO cardiac muscle cell RGD PMID:26333362 RGD:11561912 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324 		JBrowse link
G Pawr pro-apoptotic WT1 regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936698:650,225...746,593
Ensembl chrNW_004936698:650,953...747,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    cellular process 15075
      cell death 1877
        programmed cell death 1877
          programmed cell death in response to reactive oxygen species 19
            hydrogen peroxide-mediated programmed cell death + 18
            singlet oxygen-mediated programmed cell death 0
Path 2
Term Annotations click to browse term
  biological_process 15969
    response to stimulus 8553
      cellular response to stimulus 7239
        cellular response to stress 1840
          cellular response to chemical stress 375
            cellular response to oxidative stress 304
              cellular response to reactive oxygen species 195
                programmed cell death in response to reactive oxygen species 19
                  hydrogen peroxide-mediated programmed cell death + 18
                  singlet oxygen-mediated programmed cell death 0
paths to the root