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ONTOLOGY REPORT - ANNOTATIONS

Term:programmed cell death in response to reactive oxygen species
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Accession:GO:0097468 term browser browse the term
Definition:Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
Synonyms:exact_synonym: PCD in response to reactive oxygen species;   reactive oxygen species-mediated PCD;   reactive oxygen species-mediated programmed cell death
 broad_synonym: PCD in response to oxidative stress;   programmed cell death in response to oxidative stress


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programmed cell death in response to reactive oxygen species term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR34A microRNA mir-34a involved_in ISO (PMID:22651868) BHF-UCL PMID:22651868 NCBI chr 5:62,485,832...62,485,897
Ensembl chr 5:62,485,832...62,485,897 		JBrowse link
G PJVK pejvakin involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:22,080,574...22,087,537
Ensembl chr36:22,040,303...22,092,249 		JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP2K4 mitogen-activated protein kinase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,142,610...36,243,673
Ensembl chr 5:36,118,388...36,241,296 		JBrowse link
G PDCD10 programmed cell death 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:32,512,109...32,553,524
Ensembl chr34:32,512,112...32,553,445 		JBrowse link
G STK25 serine/threonine kinase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:51,425,597...51,434,479
Ensembl chr25:51,425,597...51,434,479 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:14652021)
(MGI:5613479|PMID:14652021)		 ParkinsonsUK-UCL PMID:14652021 MGI:5613479 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:32412792 RGD:150429761 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275 		JBrowse link
G GLRX glutaredoxin ISO RGD PMID:19938943 RGD:9686063 NCBI chr 3:13,795,609...13,804,732
Ensembl chr 3:13,795,817...13,803,895 		JBrowse link
G HGF hepatocyte growth factor involved_in ISO (PMID:20655899) BHF-UCL PMID:20655899 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G HK3 hexokinase 3 involved_in ISO PMID:21072205 CACAO PMID:21072205 RGD:10047370 NCBI chr 4:36,471,389...36,491,757
Ensembl chr 4:36,472,949...36,529,903 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MIR132 microRNA mir-132 ISO RGD PMID:23585551 RGD:7327146 NCBI chr 9:46,153,531...46,153,590
Ensembl chr 9:46,153,511...46,153,611 		JBrowse link
G MIR21 microRNA mir-21 ISO RGD PMID:19336275 RGD:41404719 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR212 microRNA mir-212 ISO RGD PMID:23585551 RGD:7327146 NCBI chr 9:46,153,913...46,153,974
Ensembl chr 9:46,153,903...46,153,984 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010)
(MGI:5574514|PMID:24947010)		 ParkinsonsUK-UCL PMID:24947010 MGI:5574514 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:426,734...431,087
Ensembl chr11:426,215...431,089 		JBrowse link
G TRAP1 TNF receptor associated protein 1 involved_in ISO PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr 6:37,544,929...37,596,789
Ensembl chr 6:37,544,580...37,597,427 		JBrowse link
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOG endonuclease G ISO RGD PMID:20594982 RGD:9685387 NCBI chr 9:54,809,470...54,812,795
Ensembl chr 9:54,809,530...54,813,042 		JBrowse link
G FOXA1 forkhead box A1 ISO RGD PMID:19649697 RGD:151665511 NCBI chr 8:16,072,629...16,083,105
Ensembl chr 8:16,079,140...16,083,807 		JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:23585551 RGD:7327146 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G FOXP1 forkhead box P1 ISO cardiac muscle cell RGD PMID:26333362 RGD:11561912 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397 		JBrowse link
G PAWR pro-apoptotic WT1 regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:22,114,014...22,159,287 JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO RGD PMID:23585551 RGD:7327146 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cell death 2087
        programmed cell death 2087
          programmed cell death in response to reactive oxygen species 23
            hydrogen peroxide-mediated programmed cell death + 21
            singlet oxygen-mediated programmed cell death 0
Path 2
Term Annotations click to browse term
  biological_process 17878
    response to stimulus 9437
      cellular response to stimulus 8001
        cellular response to stress 1971
          cellular response to chemical stress 409
            cellular response to oxidative stress 321
              cellular response to reactive oxygen species 208
                programmed cell death in response to reactive oxygen species 23
                  hydrogen peroxide-mediated programmed cell death + 21
                  singlet oxygen-mediated programmed cell death 0
paths to the root