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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:ubiquitin-dependent glycoprotein ERAD pathway
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Accession:GO:0097466 term browser browse the term
Definition:An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.
Synonyms:exact_synonym: ER-associated glycoprotein degradation;   glycoprotein ERAD;   gpERAD
 broad_synonym: misfolded or incompletely synthesized glycoprotein catabolic process


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Path 1
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      response to chemical 6021
        response to oxygen-containing compound 2422
          response to glycoprotein 9
            ubiquitin-dependent glycoprotein ERAD pathway 0
              mannose trimming involved in glycoprotein ERAD pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      catabolic process 2859
        organic substance catabolic process 2402
          organonitrogen compound catabolic process 1594
            protein catabolic process 1116
              proteolysis involved in protein catabolic process 862
                proteasomal protein catabolic process 590
                  ERAD pathway 106
                    ubiquitin-dependent glycoprotein ERAD pathway 0
                      mannose trimming involved in glycoprotein ERAD pathway 0
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