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ONTOLOGY REPORT - ANNOTATIONS


Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:31,822,592...31,947,624 JBrowse link
G Gpx1 glutathione peroxidase 1 colocalizes_with
located_in
ISO
IEA
(PMID:18853169) ParkinsonsUK-UCL
Ensembl
PMID:18853169 GO_REF:0000107 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Nub1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chrNW_004936527:6,726,363...6,756,445 JBrowse link
G Sqstm1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chrNW_004936739:943,080...955,296 JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:9,091,115...9,102,101 JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15331
    cellular anatomical entity 15219
      intracellular anatomical structure 11671
        inclusion body 81
          Lewy body 7
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root