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ONTOLOGY REPORT - ANNOTATIONS

Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:59,295,837...59,395,469
Ensembl chr 9:59,295,541...59,393,901 		JBrowse link
G Gpx1 glutathione peroxidase 1 colocalizes_with ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 located_in IDA (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chr 5:24,890,813...24,915,376
Ensembl chr 5:24,890,530...24,915,376 		JBrowse link
G Sqstm1 sequestosome 1 located_in ISO MGI
RGD		 PMID:15158159 GO_REF:0000096 MGI:4417868 RGD:13210572 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Fbxo7 F-box protein 7 located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005 		JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28527
    cellular anatomical entity 19410
      intracellular anatomical structure 14531
        inclusion body 83
          Lewy body 7
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root