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ONTOLOGY REPORT - ANNOTATIONS


Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa



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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 located_in IDA (PMID:21590270) UniProt
UniProt
PMID:21590270 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
JBrowse link
G GPX1 glutathione peroxidase 1 colocalizes_with IDA (PMID:18853169) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:18853169 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chr 7:151,341,812...151,378,449
Ensembl chr 7:151,341,772...151,378,449
JBrowse link
G PINK1 PTEN induced kinase 1 located_in TAS (PMID:24522549) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:24522549 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase located_in TAS (PMID:24522549) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:24522549 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
JBrowse link
G SQSTM1 sequestosome 1 located_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:15158159 GO_REF:0000107 RGD:13210572 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IDA (PMID:23656991) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:23656991 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829
JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 located_in IDA (PMID:23392669) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:23392669 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G FBXO7 F-box protein 7 located_in IDA (PMID:23656991) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:23656991 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IDA (PMID:19788048) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:19788048 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IDA (PMID:23656991) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:23656991 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20602
    cellular anatomical entity 20215
      intracellular anatomical structure 16098
        inclusion body 85
          Lewy body 9
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root