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ONTOLOGY REPORT - ANNOTATIONS


Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa



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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:21590270) UniProt PMID:21590270 NCBI chr30:35,927,277...36,040,168
Ensembl chr30:35,927,233...36,108,381
JBrowse link
G GPX1 glutathione peroxidase 1 colocalizes_with
located_in
ISO
IEA
(PMID:18853169) ParkinsonsUK-UCL
Ensembl
Ensembl
PMID:18853169 GO_REF:0000107 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260
JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chr16:15,355,237...15,382,284
Ensembl chr16:15,352,476...15,381,095
JBrowse link
G SQSTM1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003
JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16888
    cellular anatomical entity 16636
      intracellular anatomical structure 12901
        inclusion body 83
          Lewy body 7
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root