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ONTOLOGY REPORT - ANNOTATIONS

Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa

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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:21590270) UniProt PMID:21590270 NCBI chrNW_004955450:4,683,118...4,737,793
Ensembl chrNW_004955450:4,683,118...4,737,994 		JBrowse link
G Gpx1 glutathione peroxidase 1 located_in ISO (PMID:18853169) ParkinsonsUK-UCL PMID:18853169 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Nub1 negative regulator of ubiquitin like proteins 1 located_in ISO (PMID:26797281) MGI PMID:26797281 NCBI chrNW_004955491:5,709,791...5,737,620
Ensembl chrNW_004955491:5,709,791...5,739,079 		JBrowse link
G Sqstm1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615 		JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 located_in ISO (PMID:23392669) ParkinsonsUK-UCL PMID:23392669 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218 		JBrowse link
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in ISO (PMID:19788048) ParkinsonsUK-UCL PMID:19788048 NCBI chrNW_004955433:14,609,275...14,621,774
Ensembl chrNW_004955433:14,608,375...14,621,839 		JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12540
    cellular anatomical entity 12383
      intracellular anatomical structure 10498
        inclusion body 73
          Lewy body 7
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root