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ONTOLOGY REPORT - ANNOTATIONS

Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 located_in IEA Ensembl GO_REF:0000107 Ensembl chr15:70,187,722...70,297,226 JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:21590270) UniProt PMID:21590270 NCBI chr15:51,423,132...51,534,278 JBrowse link
G GPX1 glutathione peroxidase 1 colocalizes_with
located_in		 ISO
IEA		 (PMID:18853169) ParkinsonsUK-UCL
Ensembl		 PMID:18853169 GO_REF:0000107 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chr 7:142,927,730...142,964,475
Ensembl chr 7:155,079,243...155,114,676 		JBrowse link
G SQSTM1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chr 5:174,960,727...174,989,946
Ensembl chr 5:182,284,436...182,299,093 		JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224 		JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249 		JBrowse link
G FBXO7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164 		JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15636
    cellular anatomical entity 15387
      intracellular anatomical structure 12089
        inclusion body 81
          Lewy body 8
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root