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ONTOLOGY REPORT - ANNOTATIONS


Term:Lewy body
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Accession:GO:0097413 term browser browse the term
Definition:Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
Synonyms:related_synonym: cytoplasmic inclusion
 xref: NIF_Subcellular:sao4933778419
 only_in_taxon: NCBITaxon:33208 ! Metazoa



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Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:21590270) RGD PMID:21590270 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
JBrowse link
G Gpx1 glutathione peroxidase 1 colocalizes_with
located_in
ISO
IEA
(PMID:18853169)
GO_REF:0000107
RGD
Ensembl
PMID:18853169 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) RGD PMID:26797281 MGI:5781275 NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694
JBrowse link
G Sqstm1 sequestosome 1 IDA RGD PMID:15158159 RGD:13210572 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) RGD PMID:23656991 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 located_in ISO (PMID:23392669) RGD PMID:23392669 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) RGD PMID:23656991 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in ISO (PMID:19788048) RGD PMID:19788048 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) RGD PMID:23656991 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19187
    cellular anatomical entity 18928
      intracellular anatomical structure 14074
        inclusion body 84
          Lewy body 7
            Lewy body core 3
            Lewy body corona 1
            classical Lewy body 1
            cortical Lewy body 0
paths to the root