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ONTOLOGY REPORT - ANNOTATIONS

Term:establishment of Sertoli cell barrier
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Accession:GO:0097368 term browser browse the term
Definition:Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.
Synonyms:exact_synonym: establishment of BTB;   establishment of SCB;   establishment of blood-testis barrier


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establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid4a AT-rich interaction domain 4A acts_upstream_of_or_within ISO MGI:2137512 (PMID:23487765) RGD PMID:23487765 NCBI chr 6:89,522,459...89,593,868
Ensembl chr 6:89,522,442...89,593,510 		JBrowse link
G Arid4b AT-rich interaction domain 4B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2444354 (PMID:23487765)		 Ensembl
RGD		 PMID:23487765 GO_REF:0000107 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906 		JBrowse link
G Flna filamin A IMP RGD PMID:22872576 RGD:7207404 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA RGD PMID:22976294 RGD:8547721 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Itgb1 integrin subunit beta 1 IEP RGD PMID:22872576 RGD:7207404 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Rab13 RAB13, member RAS oncogene family involved_in IMP PMID:23419316 UniProt PMID:23419316 RGD:8554106 NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036 		JBrowse link
negative regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha IDA RGD PMID:18057314 RGD:10046056 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
positive regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:28880272 RGD:13703098 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:22777528 RGD:11567213 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:26678449 RGD:11532443 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      developmental process involved in reproduction 1235
        Sertoli cell development 30
          establishment of Sertoli cell barrier 10
            negative regulation of establishment of Sertoli cell barrier 1
            positive regulation of establishment of Sertoli cell barrier 3
            regulation of establishment of Sertoli cell barrier + 4
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            reproductive system development 438
              reproductive structure development 433
                gonad development 341
                  male gonad development 210
                    Sertoli cell differentiation 38
                      Sertoli cell development 30
                        establishment of Sertoli cell barrier 10
                          negative regulation of establishment of Sertoli cell barrier 1
                          positive regulation of establishment of Sertoli cell barrier 3
                          regulation of establishment of Sertoli cell barrier + 4
paths to the root