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ONTOLOGY REPORT - ANNOTATIONS


Term:establishment of Sertoli cell barrier
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Accession:GO:0097368 term browser browse the term
Definition:Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.
Synonyms:exact_synonym: establishment of BTB;   establishment of SCB;   establishment of blood-testis barrier


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establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid4a AT-rich interaction domain 4A acts_upstream_of_or_within ISO MGI:2137512 (MGI:5571188|PMID:23487765) RGD PMID:23487765 MGI:5571188 NCBI chr 6:93,461,713...93,532,901
Ensembl chr 6:93,461,713...93,532,901
JBrowse link
G Arid4b AT-rich interaction domain 4B acts_upstream_of_or_within ISO MGI:2444354 (MGI:5571188|PMID:23487765) RGD PMID:23487765 MGI:5571188 NCBI chr17:53,831,353...53,955,897
Ensembl chr17:53,833,023...53,915,076
Ensembl chr17:53,833,023...53,915,076
JBrowse link
G Flna filamin A IMP RGD PMID:22872576 RGD:7207404 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA RGD PMID:22976294 RGD:8547721 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Itgb1 integrin subunit beta 1 IEP RGD PMID:22872576 RGD:7207404 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Rab13 RAB13, member RAS oncogene family involved_in IMP PMID:23419316 UniProt PMID:23419316 RGD:8554106 NCBI chr 2:189,581,209...189,586,358
Ensembl chr 2:189,581,644...189,586,338
JBrowse link
negative regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha IDA RGD PMID:18057314 RGD:10046056 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
positive regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:28880272 RGD:13703098 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:22777528 RGD:11567213 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    reproductive process 1795
      developmental process involved in reproduction 1187
        Sertoli cell development 28
          establishment of Sertoli cell barrier 9
            negative regulation of establishment of Sertoli cell barrier 1
            positive regulation of establishment of Sertoli cell barrier 2
            regulation of establishment of Sertoli cell barrier + 3
Path 2
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      anatomical structure development 6259
        multicellular organism development 5741
          system development 5284
            reproductive system development 589
              reproductive structure development 584
                gonad development 327
                  male gonad development 202
                    Sertoli cell differentiation 34
                      Sertoli cell development 28
                        establishment of Sertoli cell barrier 9
                          negative regulation of establishment of Sertoli cell barrier 1
                          positive regulation of establishment of Sertoli cell barrier 2
                          regulation of establishment of Sertoli cell barrier + 3
paths to the root