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ONTOLOGY REPORT - ANNOTATIONS

Term:programmed necrotic cell death
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Accession:GO:0097300 term browser browse the term
Definition:A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
Comment:This term may be used when annotating instances of programmed cell death characterized by necrotic morphology where the involvement of RIPK1 and/or RIPK3 is not shown. See PMID:23818611 for some examples.
Synonyms:exact_synonym: programmed cell death by necrosis
 broad_synonym: regulated necrosis

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programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg9a autophagy related 9A involved_in ISO (MGI:5906103|PMID:27811852) UniProt PMID:27811852 MGI:5906103 NCBI chrNW_004936569:1,635,958...1,645,600
Ensembl chrNW_004936569:1,635,836...1,645,815 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23770239) Ensembl
MGI		 PMID:23770239 GO_REF:0000107 NCBI chrNW_004936664:3,477,750...3,482,489
Ensembl chrNW_004936664:3,475,543...3,481,533 		JBrowse link
G LOC101954543 caspase-1-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936551:3,230,060...3,240,496 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18007661) Ensembl
MGI		 PMID:18007661 GO_REF:0000107 NCBI chrNW_004936560:3,988,696...4,197,953
Ensembl chrNW_004936560:3,989,420...4,197,501 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO (PMID:18007661) MGI PMID:18007661 NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907 		JBrowse link
G Nlrp1 NLR family pyrin domain containing 1 acts_upstream_of_or_within ISO (PMID:16429160) MGI PMID:16429160 NCBI chrNW_004936677:2,248,153...2,290,802
Ensembl chrNW_004936677:2,248,903...2,289,151 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839 		JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18007661) Ensembl
MGI		 PMID:18007661 GO_REF:0000107 NCBI chrNW_004936669:1,004,891...1,034,913
Ensembl chrNW_004936669:1,003,528...1,029,249 		JBrowse link
execution phase of necroptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlkl mixed lineage kinase domain like pseudokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,591,483...23,618,152
Ensembl chrNW_004936475:23,591,493...23,618,660 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839 		JBrowse link
necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat containing 2 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555 		JBrowse link
G Casp8 caspase 8 acts_upstream_of ISO (PMID:21368763)
(PMID:21402742)
(PMID:22037414)		 MGI PMID:21368763 PMID:21402742 PMID:22037414 NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922 		JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator acts_upstream_of ISO (PMID:21368763) MGI PMID:21368763 NCBI chrNW_004936726:381,888...425,565
Ensembl chrNW_004936726:381,835...423,311 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097)
(PMID:22037414)
(PMID:27545878)		 Ensembl
MGI
TreeGrafter		 PMID:21052097 PMID:22037414 PMID:27545878 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118 		JBrowse link
G Dnm1l dynamin 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:3,576,357...3,632,423
Ensembl chrNW_004936607:3,576,392...3,632,554 		JBrowse link
G Faslg Fas ligand involved_in ISO (PMID:11101870) BHF-UCL PMID:11101870 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936614:4,724,935...4,772,373
Ensembl chrNW_004936614:4,725,250...4,772,153 		JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:930,986...1,064,223
Ensembl chrNW_004936733:930,972...1,064,229 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,591,483...23,618,152
Ensembl chrNW_004936475:23,591,493...23,618,660 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30248149) Ensembl
MGI		 PMID:30248149 GO_REF:0000107 NCBI chrNW_004936888:145,642...151,716
Ensembl chrNW_004936888:145,642...151,182 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22726440) Ensembl
MGI		 PMID:22726440 GO_REF:0000107 NCBI chrNW_004936521:404,574...411,381
Ensembl chrNW_004936521:404,544...411,539 		JBrowse link
G Pygl glycogen phosphorylase L involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19498109) Ensembl
MGI		 PMID:19498109 GO_REF:0000107 NCBI chrNW_004936495:14,692,688...14,728,663
Ensembl chrNW_004936495:14,692,332...14,730,231 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22037414)
(PMID:19498109)
(PMID:21052097)		 Ensembl
MGI		 PMID:19498109 PMID:21052097 PMID:22037414 GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:21402742)
(PMID:21368763)
(PMID:19498109)
(PMID:22675671)
(PMID:22037414)		 Ensembl
MGI
UniProt		 PMID:19498109 PMID:21368763 PMID:21402742 PMID:22037414 PMID:22675671 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839 		JBrowse link
G Spata2 spermatogenesis associated 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:27545878) Ensembl
MGI		 PMID:27545878 GO_REF:0000107 NCBI chrNW_004936514:4,506,015...4,513,040
Ensembl chrNW_004936514:4,508,837...4,513,264 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22726440) Ensembl
MGI		 PMID:22726440 GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425 		JBrowse link
G Trpm7 transient receptor potential cation channel subfamily M member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:12,564,617...12,666,229
Ensembl chrNW_004936471:12,565,054...12,665,962 		JBrowse link
necroptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:633,501...639,412
Ensembl chrNW_004936599:633,330...639,456 		JBrowse link
G Fas Fas cell surface death receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:16507998)
(PMID:21052097)		 BHF-UCL
MGI		 PMID:16507998 PMID:21052097 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand involved_in ISO (PMID:11101870) BHF-UCL PMID:11101870 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,591,483...23,618,152
Ensembl chrNW_004936475:23,591,493...23,618,660 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839 		JBrowse link
G Tlr3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:19498109)
(PMID:21368763)
(PMID:22037414)
(PMID:21052097)		 UniProt
MGI
Ensembl		 PMID:19498109 PMID:21052097 PMID:21368763 PMID:22037414 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766 		JBrowse link
negative regulation of necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adprs ADP-ribosylserine hydrolase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:18,580,615...18,586,325
Ensembl chrNW_004936474:18,580,615...18,586,307 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) BHF-UCL PMID:22711822 NCBI chrNW_004936580:5,213,323...5,230,861
Ensembl chrNW_004936580:5,214,401...5,245,021 		JBrowse link
G Birc2 baculoviral IAP repeat containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) TreeGrafter
MGI		 PMID:21052097 GO_REF:0000118 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555 		JBrowse link
G Birc7 baculoviral IAP repeat containing 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:344,837...350,950
Ensembl chrNW_004936745:345,635...351,749 		JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22037414)
(PMID:22089168)
(PMID:21402742)
(PMID:21368763)		 Ensembl
MGI		 PMID:21368763 PMID:21402742 PMID:22037414 PMID:22089168 GO_REF:0000107 NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922 		JBrowse link
G Cav1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170 		JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator acts_upstream_of_or_within ISO (PMID:21368763)
(PMID:22089168)
(PMID:22675671)		 MGI PMID:21368763 PMID:22089168 PMID:22675671 NCBI chrNW_004936726:381,888...425,565
Ensembl chrNW_004936726:381,835...423,311 		JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22675671)
(PMID:22089168)		 Ensembl
MGI		 PMID:22089168 PMID:22675671 GO_REF:0000107 NCBI chrNW_004936599:633,501...639,412
Ensembl chrNW_004936599:633,330...639,456 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chrNW_004936510:1,772,971...1,836,075
Ensembl chrNW_004936510:1,772,971...1,837,765 		JBrowse link
G Mutyh mutY DNA glycosylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:26,484,316...26,492,652
Ensembl chrNW_004936474:26,481,211...26,493,019 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:8,985,074...9,040,863
Ensembl chrNW_004936491:8,985,074...9,041,244 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22089168) Ensembl
MGI		 PMID:22089168 GO_REF:0000107 NCBI chrNW_004936485:18,057,569...18,071,787
Ensembl chrNW_004936485:18,057,534...18,071,816 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
G Rnf31 ring finger protein 31 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22089168) Ensembl
MGI		 PMID:22089168 GO_REF:0000107 NCBI chrNW_004936722:385,972...397,718
Ensembl chrNW_004936722:385,971...398,030 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:4,130,461...4,135,046
Ensembl chrNW_004936554:4,130,459...4,135,044 		JBrowse link
negative regulation of programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,644,299...17,648,213
Ensembl chrNW_004936475:17,644,653...17,648,211 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,998,064...11,999,431
Ensembl chrNW_004936501:11,997,834...11,999,709 		JBrowse link
negative regulation of ripoptosome assembly involved in necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat containing 2 acts_upstream_of_or_within ISO (PMID:21052097) MGI PMID:21052097 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:21052097) MGI PMID:21052097 NCBI chrNW_004936510:1,772,971...1,836,075
Ensembl chrNW_004936510:1,772,971...1,837,765 		JBrowse link
positive regulation of necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor mitochondria associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:1,441,508...1,477,133
Ensembl chrNW_004936479:1,441,437...1,478,107 		JBrowse link
G Casp6 caspase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936563:912,502...920,025
Ensembl chrNW_004936563:911,304...919,119 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (MGI:2182480|PMID:12114629), (MGI:3695559|PMID:17116882) UniProt PMID:12114629 PMID:17116882 MGI:2182480 MGI:3695559 NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA
ISO		 Ensembl
RGD		 PMID:22372834 PMID:23386613 GO_REF:0000107 RGD:7777171 RGD:7777172 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISO (PMID:32200799)
(MGI:5907398|PMID:27819682), (MGI:5907399|PMID:27819681), (MGI:6442612|PMID:27917412), (MGI:6453154|PMID:32350114), (MGI:6490907|PMID:33109609)
(MGI:6095612|PMID:29073079), (MGI:6434626|PMID:32296175), (MGI:6436371|PMID:22423968), (MGI:6436393|PMID:30050136), (MGI:6436412|PMID:32200799), (MGI:6436445|PMID:27746097)		 UniProt PMID:22423968 PMID:27746097 PMID:27819681 PMID:27819682 PMID:27917412 More... MGI:5907398 MGI:5907399 MGI:6095612 MGI:6434626 MGI:6436371 MGI:6436393 MGI:6436412 MGI:6436445 MGI:6442612 MGI:6453154 MGI:6490907 NCBI chrNW_004936530:398,980...408,798 JBrowse link
positive regulation of programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
G Tp53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425 		JBrowse link
G Tspo translocator protein ISO RGD PMID:15284300 RGD:2317153 NCBI chrNW_004936718:992,301...995,172
Ensembl chrNW_004936718:992,301...995,995 		JBrowse link
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh7 alkB homolog 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:3,733,103...3,734,770
Ensembl chrNW_004936588:3,732,526...3,737,219 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22493254) Ensembl
MGI		 PMID:22493254 GO_REF:0000107 NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936521:404,574...411,381
Ensembl chrNW_004936521:404,544...411,539 		JBrowse link
regulation of necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat containing 2 involved_in ISO (PMID:21737330) UniProt PMID:21737330 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555 		JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936726:381,888...425,565
Ensembl chrNW_004936726:381,835...423,311 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118 		JBrowse link
G Fadd Fas associated via death domain ISO RGD PMID:26038570 RGD:11341801 NCBI chrNW_004936599:633,501...639,412
Ensembl chrNW_004936599:633,330...639,456 		JBrowse link
G Spata2 spermatogenesis associated 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936514:4,506,015...4,513,040
Ensembl chrNW_004936514:4,508,837...4,513,264 		JBrowse link
regulation of programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:104,666...141,761
Ensembl chrNW_004936554:104,229...141,512 		JBrowse link
ripoptosome assembly involved in necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22037414) Ensembl
MGI		 PMID:22037414 GO_REF:0000107 NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) Ensembl
MGI		 PMID:21052097 GO_REF:0000107 NCBI chrNW_004936534:9,326,307...9,361,943
Ensembl chrNW_004936534:9,325,249...9,361,949 		JBrowse link
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  biological_process 15871
    cellular process 15001
      cell death 1877
        programmed cell death 1877
          programmed necrotic cell death 50
            necroptotic process + 37
            negative regulation of programmed necrotic cell death + 19
            positive regulation of programmed necrotic cell death + 8
            programmed necrotic cell death in response to starvation 0
            regulation of mitochondrial membrane permeability involved in programmed necrotic cell death 3
            regulation of programmed necrotic cell death + 29
paths to the root