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ONTOLOGY REPORT - ANNOTATIONS

Term:20-aldehyde-leukotriene B4 20-monooxygenase activity
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Accession:GO:0097259 term browser browse the term
Definition:Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].
Synonyms:xref: RHEA:48672;   reactome:R-HSA-2161792 "20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3";   reactome:R-HSA-2161979 "20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH"


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20-aldehyde-leukotriene B4 20-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 enables ISO (PMID:9675028) RGD PMID:9675028 NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
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  molecular_function 21054
    catalytic activity 6213
      oxidoreductase activity 865
        monooxygenase activity 165
          20-aldehyde-leukotriene B4 20-monooxygenase activity 1
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